Rapamycin Frequently Asked Questions (FAQ)

RapaFAQ

Rapamycin: The Gold Standard of Life Extension Drugs

Rapamycin is, by far, the world’s leading candidate for an effective and accessible longevity (anti-aging) drug. Nothing else comes close. If you’re interested in a longer, healthier life you may want to read on and join the thousands of people already using it to improve their lives. We estimate about 20,000 people are taking rapamycin for longevity purposes today, as of Sept. 2024, and increasing quickly, at about 300% per year. At a minimum, you probably want to learn as much as you can about it and keep a close eye on the research going forward.

Rapamycin is considered by many geroscience researchers to be the “gold standard” of longevity drugs; the healthy lifespan improvement seen in animal trials are consistently the best of any drug (typically 15% to 30% lifespan improvement). It increases healthspan and lifespan in every organism its been tested in; from yeast, to flies, to worms, to fish, to mice, to rats, and now monkeys (over a billion years of evolution). It has the most reproducible life extension effect, having been tested and retested by many different labs around the world in a wide variety of different species of organisms and animals. Over 29 rapamycin lifespan mice studies have been completed with positive results. Rapamycin also seems to slow, or reverse, aging in many different organs. And, rapamycin is an FDA -approved drug that has been in use for over 20 years, by hundreds of thousands of people (in cancer and organ transplant treatment regimens) and its now classified as a generic drug, so it is inexpensive to buy.

BUT, rapamycin is also a serious drug that can have serious side effects, depending on how its dosed and other factors. This is not a risk-free drug (no drugs are). If you are considering using rapamycin be SURE to spend a few months to read the literature here, and watch the videos, so you can make an informed decision, ideally working in concert with a doctor. There can be negative side effects (typically dose-dependent) like increases in lipid levels or blood glucose levels, so many people do periodic (every 3 months or so) blood testing to check for these potential issues, and make adjustments based on test results Don’t just rush into taking rapamycin because you heard a podcast mention it. Take your time, read as much as you can of the information below, and follow the discussions in our forum.

Rapamycin Basics

Learn More about Rapamycin

Benefits of Rapamycin

Side Effects of Rapamycin

Tracking Your Biomarkers and Results

People Write About Their Experiences with Rapamycin

Rapamycin, etc. for Aging Skin and Hair, Oral Health

Rapamycin and Exercise / Muscle Growth

Surveys & Polls of Rapamycin Users

How to Use / Dose Rapamycin in Anti-aging Applications

How to get Rapamycin Prescription, How to Buy Rapamycin

Why Consider Everolimus instead of Rapamycin (Sirolimus)

Rapamycin for Dogs, Cats, Horses

Other Top Longevity Drugs:

IGF-1 Lowering Drugs for Longevity

Anti-Aging Supplements:

  • Astaxanthin (Preliminary NIA ITP results suggest a 12% median lifespan improvement in mice)
  • Glycine and Gly/NAC
  • Protandim, a mixture of botanical extracts that activate Nrf2, extended median lifespan in males only. (7% median lifespan increase)

Other Longevity Strategies (treatments):

Longevity Clinics

Longevity clinics are health optimization and preventative medicine focused healthcare centers that provide health evaluations and early risk identification of potential disease processes. We believe that this preventative focus is the future of healthcare (compared to the “sick care” of today where they wait until you get sick before they do much of anything), but right now the full services are only available to people who want to spend $5,000 to $100,000 per year. Following are some details on perhaps the leading longevity centers in the world today, and the services they offer.

The History of Rapamycin

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Why Take Rapamycin? (part 2)
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Why Rapamycin is the Gold Standard of Longevity Interventions - Matt Kaeberlein Video
Dosing Rapamycin and Infection Concerns
Pre Rapamycin Lab Work Recommended?
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One Side Effect Not Many Talk About - Metallic Taste in Mouth
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Rapamycin & Marijuana / Kratom
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Rapamycin Dosage
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Where to buy Rapamycin In India to look younger
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Question on starting strategy-Rapamycin
Where & How do I Start Rapamycin?
Telemedicine services for longevity medication prescriptions?
Once a week(Why)?
Interested in starting Rapamycin (in SF Bay Area)
Simple Introduction - 35 Year Old Software Engineer
Hevolution Foundation, Saudi $ Billions into Anti-Aging
Rapamycin Coverage in Podcasts
Anti-aging Benefits of Rapamycin, Personal Experiences (part 2)
Starting soon, my story
New to the Forum - First time purchasing Rapamycin
New to the Forum - First time purchasing Rapamycin
Starting rapamycin next month - 27 years old
Rapamycin Benefits and Side Effects
Before/after photos?
New to Rapamycin? Start Here
Canadian trying to buy rapamycin
Rapamycin and resistance and endurance training
What dose of Rapamycin to take as a complete newcomer
For Those Who Take Indian Generic Rapamycin, Which do you take?
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Grapefruit vs pomelo while taking rapamycin?
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Rapamycin Questions from a New User
Rapamycin Update - What You Need To Know (Modern Healthspan)
Canagliflozin - Another Top Longevity Drug
Supplements/Pharmaceuticals that impact Rapamycin Effectiveness
Starting dosage? With food?
2 tablets vs. 3 rapamycin tablets
Guy 77 Yrs Old, mostly healthy, thinking of starting Rapamycin
Guy 77 Yrs Old, mostly healthy, thinking of starting Rapamycin
I will start rapamycin regimen shortly
New rapamycin user question - Any Suggestions on dosing based on weight?
Rapamycin prevent muscle building
Len5742 - My Rapamycin Diary
Bryan Johnson, Is he the New Poster Child for Rapamycin Use?
Taking without dr. Prescription
35 Year Old Active Dude wants to give rapamycin a shot, what metrics to track?
Low dose vs. High dose Rapamycin
Fatigue - Side Effect
Does rapamycin slow aging or just prevent cancer?
Is Bryan Johnson the New Poster Child for Rapamycin Use?
Rationale for Rapamycin Dosage/Frequency
Longevity Interest in China
How does Rapamycin make you feel?