I used to not care about wrinkles or skin aging. However, upon reflection (pun intended) I realize that looking younger helps your self opinion and therefore reduces stress and encourages many helpful psychological processes. It starts a virtuous cycle that enhances self-esteem and physical and psychological health. I have just purchased two tubes of Differin cream from iHerb. I was looking for something more effective than my normal moisturizer anyway.
(PS iHerb has a 22% off discount running for everything for the next two days. Code: SINGLESDAY22)
I think most dermatologists recommend prescription level retinoic acid / Retin A / tretinoin creams (.1% or .05%) - they are cheap as dirt from the same Indian pharmacies that people buy rapamycin from. Typically $7 to $12 for a 15g or 30 g tube.
The Differin Adapalene was recommended over tretinoin by Dr. Stanfield in the above video as it is newer and more effective than tretinoin. He did mention that tretinoin had been the superior brand before differin and that it is still a great option.
Make sure that you start retinoic acid at very small quantity, and increase the quantity in very slowly pace.(Ex: 1 time a week for 1 month, then 2 times a week for 1 month, then 3 times a week for 1 month…), even you start at very slowly pace, you may still experience irritation, burn, and redness, that’s normal side effect, don’t worry about it.
I am oily skin, and I have used tretinoin for years, I don’t have any wrinkle on my face (I am near 30s), however if you are dry skin, you have much higher chance experiencing pain when using retinoic acid.
Research shows that retinol has similar anti-aging effect of retinoic acid (tretinoin, adapalene…) , but retinol is more tolerant than retinoic acid, if you can’t tolerate retinoic acid, you can try retinol instead, both retinol and retinoic acid are cheap, retinoic acid is approximately 10~20 times equivalent to retinol (ex: 0.1% tretinoin is equal to 1% retinol)
I do periodic treatments with 0.05% tretinoin cream. For the first 3-4 weeks my skin usually gets very dry, irritated and starts flaking but not so this time when also using rapamycin, just a tiny bit of flaking in some areas
The best and easiest way to reverse skin aging and maintain youthful appearance is to do mesotherapy once every 2-3 months. The effect is immediate and long lasting. Mesotherapy is a procedure of injecting small amounts of HA with vitamins superficially into skin (up to 2 mm depth) with distance of 1/4 -inch between injections with needle 32 g (very thin). There are many products available. I tried many of them. My favorite is CytoCare 532. I’m 67 and don’t have wrinkles. My skin (color, tone, absence of any blemishes, etc) is the same as it was 30 years ago.
In the present study, although mild clinical improvement in skin texture was observed in some study participants (n = 2) after the third session, subjective, as well as objective, quantitative evaluation suggested that mesotherapy treatment utilizing the protocol established in this study has no significant beneficial effect in reversing the signs of skin aging
Just quick search, I don’t know if mesotherapy is really effective, do you have more information about it?
There are several ways to keep our skin healthy and looking good. Mybe everyone will find the “formula” that works for them! I have been applying a homemade Rapa cream to my face daily for 20 months with good results. I know that rapa does not cross the skin and enter the bloodstream, but as I am evaluating adding Dasatinibe to the “formula”, I do not know if this drug also do not cross and enter in the bloodstream…
It’s really effective! Don’t have information besides my own experience with it for approx 8 years. I do it regularly (myself) and have wonderful results. It’s very easy to learn how to do it yourself.