Can rapamycin and metformin be taken together?

#1

Can rapamycin and metformin be taken together?

Thanks.

#2

Rapamycin and metformin are synergistic and should be taken together, IMHO. Metformin blunts some of the negative side effects of Rapamycin and enhances some of the positives.

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#3

There are a ton of discussions on this in the past; I recommend you review some of them: (there is a search feature on the top right corner of the page for doing this - the “magnifying glass” icon.

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#4

I do take metformin every day (500mg after each meal at 12:00 and 18:00), what I mean is if I take rapamycin after lunch weekly, should I skip taking metformin after this meal? I wonder if metformin affect the absorption of rapamycin?

thanks.

#5

Meanwhile, I also take 300mg of canagliflozin 30min before lunch and 200mg of acarbose with each meal everyday. I also wonder if they will affect the absorption of rapamycin once a week? (I take rapamycin after lunch)

thanks

#6

Metformin will increase the absorption of Rapamycin by a small amount.

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#7

Metformin will increase the absorption of Rapamycin; Grok thinks it’s synergetic.

A new discussion by Matt K on rapamycin. Time Stamp 26 min

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