Intramuscular (IM) + Intranasal (IN) Rapamycin - A new paradigm for human longevity translation

I posted on this in another thread.

Moving goal posts for anemia, and iron deficient anemia clinical definitions. In general looking at the totality of my intervention, low iron, low ferritin, low saturation, low hemoglobin, low MCV, high RDW. These are all at/near anemic levels.

My Aug 3, labs, I was clinically iron deficient anemia.

Unless you have been donating blood regularly and/or have very low iron markers, in ill health, and plan to take high dose rapamycin, I wouldn’t worry too much about iron. But of course, you have to monitor everything on rapamycin. If I had continued donating blood on my normal historical 8 week cycle during this high dose intervention, my iron would have tanked much lower (I was near clinical anemia BEFORE starting the intervention), and would have been very interesting to observe if I remained asymptomatic. Just supports my thesis…modern meat eating humans have WAY more iron stored in tissue than blood markers elucidate (excess iron is pro aging). The reference values are far too high. 99% of the population has FAR higher iron stores than me, yet I’m asymptomatic. But I have been adapting to dumping iron for over 5 years and a high endurance exerciser re O2 efficiency…so I am likely not a normal iron physiological reference.

Ferritin is a relatively poor marker. I’d focus on iron plasma, hemoglobin, saturation and your CBC. Don’t forget to test sirolimus trough at every panel.



@MAC You are awesome. :slight_smile: Thanks for all of this.

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What are your thoughts about the potential for mTOR2 inhibition?

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Amazing overview… because of you MAC I am doing a lot more testing and liking the information it provides… flying a little less blind. DEXA, Coronary Calcium Scan, Labcorp sirolimus trough and post dose levels with GFJ… and without , ApoB… etc.

I highly recommend everyone take your lead and do the testing - look under the hood.

Thanks buddy!!


Somatropin is just one of the cheaper variants of HGH. However, HGH itself isn’t anything new. It’s been used in various therapies for decades, particularly for teens that have low growth hormone (the most famous example being Lionel Messi).

It has a lot of pretty nasty side effects, though, most notably its diabetogenic effect. It’s also something that seems to accelerate aging when tested in various animal models. This doesn’t matter as much to bodybuilders, but to people who want longer lifespan in addition to healthspan, it’s not ideal.


that person who went to the hospital likely did not need to. eventually the infection would have subsided as mine did after using tap water in philippines which i thought was ok but now know it likely was not since i got bad diarhhea from just drinking it for the first time in another place. i always used sterile water at home but did not want to have to take extra weight of baggage so now just use boiled i assume drinking water in PI which most all locals only drink also.

yea i was doing hgh but due to the high cost years ago switched to mk677 which can be taken orally as i do about 20mg/day and much cheaper than hgh.

WHAT THE FUCK! You injected using goddamned tap water? In the Phillippines!?!? How are you even alive? Do you even have the limb you injected into?

And you even got an infection? Did you even go to the damn hospital? What do you mean by “subsided?” Did you literally just wait it out?

For the love of all that is holy, please STOP. You are fucking scaring me. Get help, now.

I’m about to faint.

How many drugs are you pumping into yourself? I’ve followed your posts across several threads, and each additional post you make is somehow more terrifying than the last.

I am normally for harm reduction, but at this point I don’t even think you are mentally sound enough to even listen to what I have to say.

I am not exaggerating when I say this. In all my time in pharma, research, and clinical laboratories, I have never seen a patient as reckless, self-endangering, and absolutely insane as you.

Please, please, please seek medical counsel. You are killing yourself. You’re going to die if you continue this behavior. Get off this forum and go to a doctor!


ofcourse i don’t go to any hospital and ofcourse i just wait it out ! oh like anyone who ever gets infection goes to the hospital. you say the most ignorant things ! And i sure as hell would never go to any doctor unless i have a reason ! specifically if he can do the surgery i want which is something i can’t do myself.

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