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Irisin Ameliorates Age-associated Sarcopenia and Metabolic Dysfunction
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20
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3584
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September 20, 2026
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Sulforaphane: how to supplement? Forms, dose, brands, timing
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131
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26722
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September 14, 2026
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How Exercise Protects You From Illness: A Million-Cell Atlas of What Regular Exercise Actually Does to Human Immunity
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0
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191
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September 19, 2026
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Turning back time: a comprehensive list of interventions that decrease next-generation epigenetic aging clocks in humans
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9
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1443
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September 20, 2026
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SUGGESTIONS? What Company or MDs can I Hire To Get Me to 120 Years of Age?
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46
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1706
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September 20, 2026
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Gut Metabolites Control Systemic Aging: The Overlooked Power of Short-Chain Fatty Acids
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2
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273
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September 20, 2026
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Non-diabetics taking SGLT2 inhibitors (Jardiance, Invokana, etc.)—what is your experience?
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101
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6134
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September 19, 2026
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Just a little humor
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473
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45785
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September 19, 2026
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Chronic Inflammation Identified as the Primary Driver of Cardiovascular Disease and Frailty
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0
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162
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September 19, 2026
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The Longevity Threshold: Mapping the Curvilinear Response of Biological Aging to Physical Activity Volume
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1
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237
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September 18, 2026
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The Heart That Beats Too Evenly: Heart Rate Variability Tracks the Aging Brain
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2
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191
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September 19, 2026
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These are the treatments dominating the business of living longer (WaPo)
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2
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193
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September 19, 2026
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AGI/ASI Timelines thread (AGI/ASI may solve longevity if it doesn't "kill us all" first)
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252
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22619
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September 19, 2026
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The Surprising Second Act of Ezetimibe
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3
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317
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September 19, 2026
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The Christ Hospital seeks volunteers for single-shot treatment that may fix high cholesterol
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1
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170
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September 19, 2026
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Why You Should Be Skeptical of Health Skeptics (Matt Fuchs)
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1
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189
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September 19, 2026
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The Big Holes in Wearable Heart Rate Variability And Readiness Scores (Article Eric Topol 19 Sep 26)
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0
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148
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September 19, 2026
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Preventing, Avoiding and Curing Cancer - The Main Cancer Thread
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196
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21509
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August 25, 2026
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Gene regulatory mechanisms downstream of DNA methylation (paper 17 Sep 26)
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0
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221
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September 19, 2026
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Hormone Replacement Therapy Shows Targeted Dementia Protection in Critical 46 to 56 Age Window
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1
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630
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September 19, 2026
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Nicotine benefits?
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44
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4754
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September 18, 2026
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Scientists discover cells that cheat death and rebuild damaged tissue
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0
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145
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September 19, 2026
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How do you minimize plastics exposure when storing pills?
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1
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177
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September 18, 2026
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[Norngroup-funded] Multimodal brain age prediction using machine learning: combining structural MRI and 5-HT2AR PET-derived features
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0
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96
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September 18, 2026
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Stem Cell Vesicles Reverse Skin Aging and Senescence by Hacking the TIMP1 and Notch1 Pathway
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2
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247
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September 18, 2026
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Fisetin Fails to Halt Aging in Healthy Mice: The Stress Threshold Hypothesis
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1
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502
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September 18, 2026
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Is anyone here on or investigating PCSK9 inhibitors?
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121
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13534
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September 18, 2026
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The Hidden Architecture of Longevity: Machine Learning Decodes 95,000 Sleep Trackers Across 1,000 Diseases
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3
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342
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September 18, 2026
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Speedometers for Aging: How Shared Biomarkers Could Fast-Track Human Longevity Drugs
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1
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299
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September 18, 2026
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Heat, Water, and the Survival of Dietary Geroprotectors
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0
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129
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September 18, 2026
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