Is the retatrutide keeping you awake at night?
That happens for me when I am binge drinking although it tends not to go over 60bpm even then.
Does anyone have a Chinese source, not only for Reta but also for tadalafil tabs, prednison tabs etc etc? From the same supplier that ships to the EU? Thank you so much.
I don’t have a good Reta source because there are so many to choose from, but I don’t advise getting tadalafil from China but instead one of the online pharmacies listed here Buy Rapamycin Online - List of Reliable Pharmacies
Here look for reliable brands selling at those online pharmacies: Generally Good Indian Pharma Companies
Peptides are better purchased from China however.
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I beg to differ 
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You’re not grey, you’re somewhere between gray and green LOL
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I’m thinking of switching from Reta to Tirz for my next order to see if it resolves the elevated HR and dysesthesia issues for me.
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I doubt it makes any difference switching from Reta to Tirze. I had about same symptoms (increase in HR, nausea and dysesthesia) from both. What actually made a difference for me was when I decided to take a 6-week break from GLP1’s and when I restarted them again (regardless of which one, Reta or Tirze) I witnessed no more side effects. I guess my body had been accustomed to GLP1’s and was ready to adjust after the break.
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Peptides gone wrong.
Been experimenting with the Retatrutide dosing. 0.5mg-1mg/week didn’t yield any noticable difference.
Worked up to 2x 1mg/week, which gave everything I wanted: No thoughts of food but a some appetite, no side effects, dropping pounds & PRs in the gym.
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Its my nature to go all in on a medicine I like for these optimal trial results but…
4mg is running through me… still haven’t caught up… Im on pace to lose 30 pounds in 3 months on it. I was “skinny fat” and now I’m bones (though I work out - Body by science)… I still have side effects… and with telmisartan 80 and the rest of my stack, I’m dead at near hypotension when I wake up (which seems to be the lowest my bp gets)… Systolic is in the 90s… and diastolic can be in the 60s with it…
I might have to just stop at 4mg, despite be seeing some of the “dose dependent” additives in the trials. ***But I also take lots of glycine which can enhance/interact the glp process which may be what’s happening here
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Wow yea you don’t want to go any further. I feel like 90 systolic can be dangerous. Stick with 4mg and see if this normalizes.
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I’d stop the Telmisartan. Seems like overkill. I was approaching some pretty low BP as well so I had to remove that.
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It’s a bit sad to see such a negative reaction from the audience in the comments. People seem resistant to something that makes their lives easier.
- The video argues that powerful GLP‑1 drugs like semaglutide and tirzepatide (used in Ozempic, Mounjaro and similar medications) represent a breakthrough because they make people feel full sooner and eat less by amplifying a natural hormone signal that controls appetite and digestion, essentially fixing biology rather than willpower alone.
- Obesity has deep biological and evolutionary roots, and modern environments with cheap palatable food overwhelm normal appetite control, making dieting and behavior changes extremely difficult.
- GLP‑1 medications have led to much greater weight loss than traditional diets, often over 15–20% of initial body weight in a year, similar to results seen with bariatric surgery.
- In addition to weight loss, these drugs can reduce the risk of major health conditions such as heart attacks, strokes and type 2 diabetes, and also improve sleep apnoea, kidney and liver function and inflammatory markers. Some benefits might occur even independent of weight lost.
- There is intriguing early evidence these drugs may reduce cravings for substances like alcohol, nicotine and opioids, potentially becoming useful in addiction treatment.
- Side effects are mostly gastrointestinal (nausea, vomiting, diarrhea, constipation) and generally transient, but more serious issues like pancreatitis or gallbladder problems can occur in a small minority of people.
- Stopping GLP‑1 treatment usually results in partial or full weight regain unless lifestyle habits have changed; many individuals therefore stay on treatment long term, but long‑term safety data for the newest drugs are still limited.
- A modelling study suggests broad use of GLP‑1 drugs among overweight adults in the United States could cut millions of cases of diabetes and heart disease and reduce premature deaths, but high prices and supply issues remain barriers.
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Semaglutide was depressive for me. Tirzepatide was good mentally, but made me very tired. Retatrutide, no mental side effects and the slight HR increase adds a bit of energy.
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Absolutely true for me on the cravings. I was a light smoker (6-7 cigs a day) who became an even lighter smoker (3-4 and I could easily quit altogether if I didn’t enjoy the sensation out of choice) and it cut my sugar cravings down significantly - as someone who was “skinny fat” in part because I enjoyed my deserts
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I’m a big fan of how GLP1RA drugs simplify our tastes. I can enjoy simpler meals and feel very satisfied with them. I don’t drink or smoke though I did in the past, and I could see how this applies to addictions.
I also wonder how this would work with ADHD in improving satisfaction with performing menial but necessary tasks.
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N=1
ADD
I take small doses of TZ or RT and zero effect on getting me to do things I don’t want to do :).
Would it be different with larger doses, I dunno?
SS-31 did make a difference and I do all sorts of things I would usually put off.
@sunshine4 oddly, LDN did for me what glp1’s do for others… no real love for anything anymore (food/wine)… but, unfortunately, it actually inspires me to eat less healthy because I need more incentive to eat.
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I think it is different with higher doses. What type of behavior modification effects are you noticing? Also, just for curiosity sake is your ADD already medicated?