In this list I would only buy from companies that also sell in Europe and the US. Higher standards.
Yes - that is probably a good idea, but it takes a little more research to figure out those companies that do sell to Western Europe and USA. I’d guess that its these from the top of my head, but if anyone knows better, please post:
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Lupin is also massive in the US: Lupin Limited - Wikipedia
And Aurobindo has apparently a strong presence in the US and Europe: https://www.fiercepharma.com/pharma/top-10-generic-drugmakers-2021-revenue
Also, with the exception of Intas, which is private, all the above companies are traded on the New York Stock Exchange. So they have the constant scrutiny of the markets.
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I notice rapacan rapamycin product is made by both Biocon and Eris. Anyone have experience or lab tests with the version made by Eris?
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No - Eris is just a marketing company, its still made by the same company Swiss Garnier. See this thread and post: Eris LifeSciences Brand of Sirolimus from India - #6 by KoolieDude17
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Indian pharma improves compliance with USFDA; fewer OAI cases in 2024
In 2023, the USFDA conducted 225 inspections, which led to 18 cases of Official Action Indicated (OAI) and 117 cases of Voluntary Action Indicated (VAI). By 2024, despite a tightening of regulatory standards, the number of inspections dropped to 206, while OAI cases fell to 14 and VAI cases reduced to 115. This highlights that the sector is increasingly aligning with global benchmarks to ensure high-quality manufacturing practices.
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Yes… but. The FDA currently has to give advanced notice of inspections to the Indian Pharma… and there have been many situations where Indian Pharma has been caught (insiders reveal) changing / modifying things to make them look better during the inspection… so I’m not super confident that things are that much better.
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Avoid Glenmark medications, it seems: (Note: these are drugs that are imported into the USA through the regular supply chain channels and distributed via regular pharmacies here in the US).
In February, the FDA found problems with cleaning and testing at the plant in Madhya Pradesh, India, which was the subject of a ProPublica investigation last year. The current recalls, listed in an FDA enforcement report last week, cover a wide range of commonly prescribed medicines, including ones that treat epilepsy, diabetes, multiple sclerosis, heart disease and high blood pressure, among other ailments. A full list of the recalled medications is available here.
Records show that Glenmark first alerted wholesalers about the recalls in a March 13 letter. That letter suggests that Glenmark pulled the drugs because of potential cross-contamination. Thomas Callaghan, Glenmark’s executive director of regulatory affairs for North America, wrote that 148 batches of the recalled medicines were made “in a shared facility” with two cholesterol-lowering drugs, ezetimibe and a combination of that drug and simvastatin.
Related:
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Do any of the pharma vendors use PP or CC?
Some do CC, but not all the time. Try Maulik: Buy Rapamycin Online - List of Reliable Pharmacies - #833 by Albina
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What do people think of Healing Pharma?
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I posted some negative info I found on HealingPharma a while back:
It’s not clear whether that was due to a relatively benign lessening of Ivermectin while it was being shipped, as all of the companies tested failed.
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Very happy with all the meds for Healing Pharma I’m taking
I would choose a larger pharma company if you can. I have used Healing for some topical products and they have been fine, but generally I prefer the larger international companies.
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What ones from Healing Pharma do you take?
Does anyone have experience with Steris pharmaceuticals? Specifically, Glicanaflozin (Canagliflozin) ?
Modafinil, telmisartan, cilnidipine, rosuvastatin, bupropion, tadalafil. Not currently taking all of that but it worked well!
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Well that’s good to know. The main issue I saw for the brand was it was underdosed. Not the biggest deal.
Regarding pharmaceutical producers (not pharmacies), I have personally toured Sun Pharma, Dr. Reddy’s Laboratories (DRL), and Biocon in India, where they demonstrated their GMP QA processes, and honestly didn’t see much difference between what they did and what the multinationals do in the US and Europe, who I also visited.
Now I’m a software designer involved developing their quality control software, I’m not a pharmaceutical manufacturing expert, so keep that in mind.
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Yeah, the problem is how consistently they apply those great in theory QA processes, because in practice they have a very high frequency of major failures of execution resulting in substantial contamination and inappropriate dosing, according to FDA findings. That’s documented. Much worse than such manufacturers in the West (who also occasionally fail). I am very wary of this. The FDA cannot make unannounced control visits to India based pharmaceutical manufacturers plants, so while they can give great tours for FDA regulators coming in during visits agreed to well in advance, we know that day to day operations can be rife with problems away from the presence of watchful eyes of FDA regulators. And that’s how we get these not infrequent FDA recalls.
Let’s face it, ordering from India you are taking a chance, period. And that’s with the big established pharmas who export internationally including the USA - these are the only ones I order personally. I wouldn’t even dream of buying a med brand made by some small, new, domestic-only Indian obscure manufacturer. I’m still playing the lottery, but trying not to go for a Russian roulette type odds. YMMV.
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