My favorite slide is the hierarchy of modern medicine showing critical thinking prism through which you evaluate longevity interventions.
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If by lazy you include not exercising, then no they won’t have the best outcome.
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Is there any one of those concierge doctors at the longevity roundtable who would be willing to give prescriptions for anti-aging drugs to someone who sees them? (Or at least, orders for rupahealth blood tests for ION blood panels? Or prescriptions for diagnostic MRI?)
Like, I met one at Zuzalu who kind of does those things but only for people in certain states.
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Interesting guy.
The following is from 2017. Choose your multiplier to get current year $
https://archive.fo/VJg0s
.org? Somehow I don’t think this is a 501(c)(3).
Look who’s part of their expert network!
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Like with anything, you offer a service for a price, and if people think it’s good value, you got a going business.
Everyone has to make a living. I have nothing against concierge docs. For my particular situation at this time, I don’t perceive the need. But who knows in the future. Right now, I see no value (for me) with these clinics.
What do you need, and what is the value proposition. At some point there may be a match. You pick a number you feel comfortable with, put your chips down, and the wheel spins. You might win, and you might lose. That’s life.
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I only met one doctor there who was prescribing rapamycin (and I added him to our list; Joseph Raffaele in NYC. I’m sure some of the others do the other services you mention, but I wasn’t surveying them; you’d have to check their websites and see what they offer. In many cases they are trying to get you to sign up for a yearly service with all-encompassing health reviews and testing… so I suspect they are not a good fit for your service interests. Longevity Clinics: Cleveland Clinic, Wellness and Preventive Medicine, Michael F. Roizen MD
But - I also noticed that Phil from Longevity Technology mentioned a survey they did of longevity clinics and many of them are prescribing rapamycin and/or metformin - so it seems you need to find the right ones:
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What evidence is there that exercising is required for the best outcome, and what’s defined as best?
Really - you need more evidence? Have you reviewed all in the forum?
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I think it’s okay to do decisions based on what you feel or think is right. But I wouldn’t say there was much good evidence posted in that thread: randomized trials, mendelian randomization studies, and clear mechanism of action for the former two.
So it’s more like artists debating how they should paint a painting rather than scientists arguing about what has the true impact and that’s OK.
Peter Attia is biased towards exercise as he is a former competitive athlete, which might be the reason he loves to bring up correlations for VO2Max but dislikes it for pepperoni’s.
Your bias is very strongly anti-exercise:
Association of Cardiorespiratory Fitness With Long-term Mortality Among Adults Undergoing Exercise Treadmill Testing
Conclusions and Relevance Cardiorespiratory fitness is inversely associated with long-term mortality with no observed upper limit of benefit. Extremely high aerobic fitness was associated with the greatest survival and was associated with benefit in older patients and those with hypertension. Cardiorespiratory fitness is a modifiable indicator of long-term mortality, and health care professionals should encourage patients to achieve and maintain high levels of fitness.
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2707428
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Increasing VO2Max isn’t free there are costs involved (calories, effort, joints, hips, injury risk, time). I feel like going on the bike and start exercising a lot based on an association study seems a bit radical. I’d have to look at hip replacement rates and things like that.
Calories need to be burned, get rid of them. Effort is good for you, it prepares you for bad times which are sure to come. With your attitude about exercise you don 't have to worry about your joints, hips, injury risk. It’s not happening. It does not take long to exercise, do it hard and get on with life.
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Reminds me of when Im watching the Resident on Netflix. Most of the time when someone goes into the ER for a minor problem, they find out they have major problems. Some even die. Old saying if you don’t want to get sick, stay out of hospitals.
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This almost never happens in real life.
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A recent interview with Dr. Jordan Shlain:
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Or eat less and save the metabolic damage.
Some exercise is good, too much is bad. Exercising to burn calories is not the right move imo.
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Almost nobody exercises too much.
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Of all the risk factors for hastening death, that is the one I worry least about.
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Is there much point in eating more just to need to exercise more to burn it off?
Exercise for cardio fitness or muscle strength is different.
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