A critical analysis of Blueprint
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Does anyone know what this device is… I think its some kind of cardiac monitoring device - but can’t seem to find it online. I’m just curious about what it is and what it does (from the Bloomberg video above):
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It looks like a 3 lead ECG to me.
In my view it is to large a unit for a modern 3 lead EKG. They manufacture 12 lead EKG with interpretation much smaller.
If that interest someone write/email him and ask?
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Hi all thank you for a great site! It seems that he takes 200mg of Acarbose on waking up (not when eating), does this make sense in terms of longevity? I just wanted to add that a paper asserting that it’s the effect on the gut microbe perhaps explains it beyond the reduction of insulin spike when taken with food.
Extension of the Life Span by Acarbose: Is It Mediated by the Gut Microbiota?
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Hi Lesta, and welcome to the forums.
On his Blueprint website he says he takes the Acarbose with (or immediately after) his morning “drink” (Green Giant).
Upon waking: The Green Giant
- 8 oz of water
- Spermidine, 2 Tbsp chlorella powder, yielding 13.5mg spermidine
- Amino Complex 7.6 g
- Creatine 2.5 g
- Collagen Peptides 20 g
- Cocoa Flavanols 500 mg
- Ceylon Cinnamon 1 tsp
Morning pills
Which makes sense from the glucose spike lowering theory of why Acarbose help’s extend life (Acarbose has about a 2 hour half life, so you want to take it fairly soon prior to eating, or “with the first bite”, and I don’t know if timing would make any difference if the gut microbiota theory is accurate for the longevity effect.
Lots more on Acarbose here: Acarbose - Details On Another Top Anti-Aging Drug
Part of the rationale behind the glucose lowering effect driving the lifespan improvement is because they found the same benefit from another drug that flattens the blood glucose spike: Canagliflozin - Another Top Anti-aging Drug
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Thank you, I take 25mg with a carb meal without gastro effects, taking 50mg does bother me. I will look into (as we all should if not doing so already) also taking it upon waking and going to sleep without food. Here is another paper that indicates it may through these mechanisms promote SIRT1 and 6. Extension of the Life Span by Acarbose: Is It Mediated by the Gut Microbiota?
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The device is the AGE reader:
It non-invasively indirectly measures AGEs in the skin by autofluorescence.
I’ve been wanting to try one for long but it’s not common in clinics. It wouldn’t be very useful for tracking purposes because AGE accumulation occurs so slowly, but it’s mostly interesting to see where you are relative to other people your age.
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A quick overview on the device, skin autofluorescence.
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Copies of the instrument did not take long.
Age Scanner Hand Held Skin Glycation Measurement Bluetooth Device
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I did look for the cost/price of the original unit from NL all where “Request A Quote”.
That means it is very expen$ive!
Ah, i actually have tried this device. Of course they have it at the Buck institute and someone had it out at the Longevity Summit during breaks testing people. You put your arm on it and it reads the skin on the underside of your arm.
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How consistent is it when you do multiple measurements of the same person?
I don’t know, nobody was doing that from what i saw.
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There is a sub-Reddit focused on Blueprint (seemingly started by Bryan Johnson). Surprisingly, nobody there seems to talking about the drugs that Bryan is taking, only the food and supplements…
If you have questions about his protocol, you might try posting them there as I suspect Bryan may respond.
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New article:
I’m 45. Will $2 million a year help me turn back the clock to 18?
Silicon Valley entrepreneur Bryan Johnson has embarked on an extreme plan to reboot his body. He reveals what it takes to defy the ageing process (1,977 vegan calories a day and a medical team of 30, for starters)
Apologies, if this has already been shared elsewhere……
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‘Powerful predictor of longevity’ implies causality.
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