I take high dose GlyNAC, while waiting for more studies to be published.
Couple questions:
- why on and off, is it one of those things that needs to be done say for couple months once per year?
and - Are you able to notice any positive effects, or is it the case where you know it might be doing something good but not easy to pinpoint (like most other substances/supplements)?
Thanks,
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wow thanks ur very knowledgeable abt this indeed.
thanks for sharing
What is a high dose? Alan Green, MD, now departed, citing this study:
offered:
āThe dose for a 70 kilo man was 9 gram of cystine and 7 grams of glycineā
For me a high dose is a dose close to 100 mg/kg body weight of each substance. (Glycine and acetylcystein)
I am using 2400mg NAC and 3g of glycine daily (split with breakfast and before bed) at age 40. I know the older you are, the more effective but there are other benefits besides glutathione restoration. These doses are below what the studies state.
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Popping in the joints is certainly not a bad thing. There is no study that even shows as much as correlation to joint damage. My teenage son can pop his joints and just sounds annoying.
From my personal experience whenever I roll, massage or do eccentrics on my I will get tight muscles/knots I will get a pop and it correlates with successful tension release, which tend correlates with less joint pain.
i am buying NOW NAC and glycine powder from iherb.
have been trying to up to 3g nac and 3-5g glycine daily.
i feel good 
i do feel like my endurance has improved as i am a jogger.
i will do 3-5g of each daily.
this NACET from iherb is probably legit but i think i will wait for more brands to come out with it before trying itā¦meanwhile it is glynac for meā¦
This link shows your full address , you might want to remove it
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Whoops okay thanks
No, it doesnāt. Only shows my town. But even if it did I doubt Iād care. Not hiding from anyone or anything LOL
What doses are the studies suggesting? Iām willing to increase my dose. Iām also doing 2400mg, I take 4x 600mg capsules every morning.
My asthma has dramatically improved since doing this.
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4.8-7.2g of each glycine and NAC
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For past few monthsā¦ I have been doing 3 g of glycine with 5 g creatinine in an short coffee for my workout energy drinkā¦ and a 2 g NAC capsule with my bedtime supplements.
Seems fine.
Have you compared NAC in the morning vs night to see which gives you better sleep?
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I take most supplements at night to work while I sleepā¦NAC, Lithium, B-12, D-3, K-2, zinc, magnesium,ā¦ etc.
In the morning coffee I take Creatine, Taurine and Collagen.
For workout Creatine and Glycineā¦ in short coffee.
When I take my 6 mg of rapamycin/sirolimus it is also at bedtime.
Typically my sleep isnt disturbedā¦ except on rapamycin night.
I have not been paying attention to my dosing and want to do get more serious about this
I see the doses are weight based, got it.
If you follow the studies, as Dessert Shores said earlier:
133mg/kg/day of NAC
100 mg/kg/day of Glycine
Or a newer study would be equal doses of each.
How are most of you taking it? Agetron, I see you are splitting them up. Do most here take them at the same time, or is at any point during the day fine. And because the dose is so high, is this something we ideally take twice per day?
I see Pure Encapsulations NAC has the highest mg in a single capsule that I can find from a reputable company. 900mg. Do comment if you know of a better optioin.
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I aim for 80 mg/kg body weight of each. taken after lunch and before dinner. And I add some small amount of NAC (approx 1500 mg) in my morning collagen.
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I use the NOW tablets 1 gm morning and night now. Glycine I take a few times a day with beverages, like Destrider said. Works well with citrulline and I throw it in with my BHB at noon. Iām sure I get more Glycine than I need.
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