Hopefully, @DrFraser, who has a dog in this fight 
will chime in, since he is promoting it with both a blog post and a YouTube video.
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Why the brain, and why now? Temple is developing a wearable designed to sit on the side of the head, near the wearer’s temple. Its aim is to continuously track cerebral blood flow – essentially, how much blood is reaching different parts of the brain over time. That may sound clinical, but the underlying idea is surprisingly intuitive.
If the heart is the engine of the body, the brain is the command center. And just like any high-performance engine, it depends on fuel. In this case, that fuel is oxygen-rich blood. When blood flow shifts, cognitive performance can shift with it – affecting focus, reaction time and decision-making under pressure.In a January podcast conversation, Goyal described Temple’s ambition as building “the ultimate wearable for elite performance athletes,” capable of measuring metrics that current devices cannot. Unlike wrist-worn trackers or smart rings, which primarily monitor heart rate, sleep cycles and activity, Temple is aiming higher up the body [2].
Most wearables today use the heart as a proxy for performance. Temple wants to look at the brain directly. It is a bold claim in a market where companies like Oura, Whoop and Garmin have spent years refining hardware and building trust with athletes. Those devices already offer increasingly sophisticated data on recovery and strain.
Temple’s wager is that the next frontier is not just how hard your heart is working, but what your brain is doing while it happens.
Tracking cerebral blood flow has traditionally required bulky machines in controlled environments. Temple’s challenge is to shrink that into something wearable, comfortable and reliable.
Introducing Brain Flow™
Blood flow to the brain is a proven signal of health and aging. Until now, it’s been hard to measure. Temple tracks Brain Flow, a proxy metric based on this very blood flow to the brain.
All of you, in one place
Track heart rate, HRV, sleep patterns, periods, activity levels, VO2 Max, and more to get an all-round view of your health.
Built for your temple
At the temple, skin is thin and rich with capillaries allowing for better readings. Worn using our gentle medical-grade tapes, Temple is comfortable, easy to wear, and non-invasive.
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I am recommending all of my patients go over to this device as it is a technological advancement on the limited approach using brachial blood pressures. I have a lot of patients with abnormal values, and making small interventions, or trialing one class of medication vs. another gives an N=1 approach on exactly what works for your vascular health. As much as we can make logical choices as physicians on what we think is the best choice to optimize a given individual’s numbers, actually getting this detailed feedback on all these parameters gives a better picture. Also interventions like increasing potassium to 3:1 ratio to sodium with sodium being limited to 1500-2000 mg and optimizing Nitrous Oxide all have interesting beneficial effects. However, this detailed data gives us better feedback on interventions than simply a brachial pressure.
@RapAdmin I wonder how much Temple adds simply to knowing central blood pressure and central pulse pressure, along with knowing that your vertebrals and carotids are wide open with no disease on MRA head/neck?
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Sadly they are not selling it to the UK as yet.
Looks like it is in development and not on sale anywhere. Nice concept if it works.
It’s a marketing scam. Nothing more than other trackers like Oura, whoops, etc.
They start by a true assertion:
Then they tell you what they really do (Note that Brain Flow is not the Blood Flow they mention above):
Basically they measure the peripheral blood at the temple.
Then they give you the measurements they take in which nothing relates to the blood flow to the brain.
Note that Oura, Whoops and the like already do all that + other things too.
Sadly they don’t do any of that. I’ve put above what they measure and pressure is not in them.
The CONNEQT Pulse discussed above in the thread is based on real science but not this.
Congratulation for them to raise 54M for basically taping an Oura ring to the temple!
A perfect fit for the current pseudo-science environment.
That said there are ways to measure the oxygen saturation in the brain with Functional near-infrared spectroscopy (NIRS) but that’s not the case here.
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How New Longevity Tech Could Help You Reach 100
Daily biometrics, smart scales and AI companions are quietly rewriting the rules of aging.
Fort: The First Wearable Built for Strength Training.
Company website:
Founders discuss their wearable and what it does:
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I got my CONNEQT BPM several days ago. At first I thought the product was just a very expensive bpm. After using it for three days I have changed my opinion and am considering retiring my OMRON bpm in favor of the CONNEQT device.
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[
Can you provide more details as to why you changed your opinion and why you are considering using this CONNEQT device over the OMRON?
I like the extended information that the CONNEQT device displays, which is over and above BP and heart rate. I am a health data nerd, so more information is almost always better IMO. I track a variety of my health metrics in spreadsheets and will be adding the extended CONNEQT data to my tracking.
Key metrics beyond basic heart rate and blood pressure include:
- Central Blood Pressure (CBP): Measures the pressure in the aorta, which is the actual load placed on vital organs like the brain and heart, rather than just the brachial pressure in the arm.
- Arterial Stiffness: Tracks the flexibility of arteries, acting as an early indicator of vascular aging.
- Central Pulse Pressure (CPP): Measures the pressure difference in the aorta, with elevated levels indicating higher risk for cardiovascular events.
- Augmentation Index (AIx): A measure of wave reflection that indicates the stiffness of the arterial system.
- Subendocardial Viability Ratio (SEVR): Also known as the, this measures the balance between oxygen supply and demand in the heart muscle.
- Waveform Analysis: Analyzes the shape, strength, and timing of blood pressure waves to determine vascular health
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Body Temp Sensor Pill Sources
Identification of Biosensor Pill Manufacturer
The text provided from the X post does not explicitly name the manufacturer of the biosensor pill. However, based on the technical parameters described—an ingestible, jelly bean-sized device measuring core body temperature via the gastrointestinal (GI) tract with an approximate 24-hour transit time—the device aligns with the exact specifications of the primary clinical-grade ingestible core temperature sensors utilized in advanced biohacking and clinical research.
Primary Candidates
- HQ Inc. (Manufacturer of the CorTemp Sensor)
- Device: CorTemp Ingestible Core Temperature Sensor.
- Specifications: Measures 23 mm x 8.6 mm (routinely compared in clinical literature to the size of a large jelly bean). It houses a telemetry system, a micro-battery, and a quartz crystal temperature sensor. It transmits real-time core temperature data to an external receiver.
- Background: Originally engineered in partnership with NASA and Johns Hopkins University to monitor astronaut physiology during spaceflight.
- BodyCap (Manufacturer of the e-Celsius Performance Pill)
- Device: e-Celsius Performance / e-Celsius Medical.
- Specifications: Measures 17.7 mm x 8.9 mm. It records temperature data continuously (typically every 30 to 60 seconds) and features internal memory capable of storing data points even when temporarily disconnected from the external monitor.
- GI Transit: Both devices typically pass through the human GI tract within 24 to 48 hours, heavily dependent on the subject’s individual gastric motility and diet.
Knowledge Gap and Uncertainty
Treating this assessment with strict accuracy, the exact brand cannot be definitively confirmed from the isolated quote provided. To achieve absolute verification, additional data is required: either a subsequent statement from the user identifying the brand, or visual identification of the external data logger utilized in the protocol (e.g., the CorTemp Data Recorder versus the BodyCap e-Viewer).
Actionable Insights for Longevity Applications
In longevity and extreme physiological optimization protocols, continuous core body temperature monitoring serves several practical functions:
- Circadian Rhythm Optimization: Precise core temperature telemetry dictates sleep architecture. A steep drop in core temperature is required to trigger and sustain slow-wave sleep. Tracking this allows for environmental and dietary interventions to force optimal sleep staging.
- Metabolic Efficiency Tracking: Chronic, fractional drops in baseline core temperature are an established biomarker of altered metabolic rate and improved mitochondrial efficiency, frequently observed in rigorous caloric restriction regimens.
- Hormetic Stress Calibration: Continuous thermometry ensures precise dosing of thermal stress. During sauna use or cold-water immersion, it provides objective data to ensure the subject achieves the necessary physiological threshold for heat shock protein (HSP) or cold shock protein expression, without risking clinical hyperthermia or hypothermia.
Would you like an analysis of how continuous core thermometry data is utilized to measure mitochondrial uncoupling in human longevity trials?
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Summary copied from social media post that brought this story to my attention:
this is actually insane
- be tech guy in australia
- adopt cancer riddled rescue dog, months to live
- not_going_to_give_you_up.mp4
- pay $3,000 to sequence her tumor DNA
- feed it to ChatGPT and AlphaFold
- zero background in biology
- identify mutated proteins, match them to drug targets
- design a custom mRNA cancer vaccine from scratch
- genomics professor is “gobsmacked” that some puppy lover did this on his own
- need ethics approval to administer it
- red tape takes longer than designing the vaccine
- 3 months, finally approved
- drive 10 hours to get rosie her first injection
- tumor halves
- coat gets glossy again
- dog is alive and happy
- professor: “if we can do this for a dog, why aren’t we rolling this out to humans?”
one man with a chatbot, and $3,000 just outperformed the entire pharmaceutical discovery pipeline.
we are going to cure so many diseases.
I dont think people realize how good things are going to get
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I like it! A pill that takes the internal temp. If he could bluetooth that to the sauna then he could (eventually) have it at the optimal temp. Without measuring we have no idea if we’re doing it right.
But, (BJ) it’s GI tract. GI track would be something else like if it spilled out and left a track on the floor.
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This is interesting… from this thread: Be careful with your supplements (A Warning from a Doctor) - #22 by rickyf
I use an app, SuppCo, to monitor my supplements and provide recommendations on dosing.
SuppCo is a health tech startup and mobile app designed to help users track, manage, and optimize their vitamin and supplement routines. Founded in 2023 by serial entrepreneur Steve Martocci and Nick Michlewicz, the platform aims to bring transparency to the fragmented supplement industry through data-backed tools. [1, 2, 3, 4]
Key features of the platform include:
- TrustScore: A proprietary rating system that evaluates over 500 brands based on 29 quality attributes, such as manufacturing standards and third-party testing.
- Stack Analysis: An algorithm that analyzes your current “supplement stack” to ensure it aligns with your health goals and provides suggestions for improvement.
- Expert Protocols: Access to specific supplement regimens developed by health experts like Dr. Mark Hyman for goals such as longevity, gut health, and brain performance.
- Smart Scheduling: Tools to help users maintain consistent dosing and track how their routine affects their performance over time.
- Independent Testing: Through their “SuppCo Tested” series, the company independently verifies if popular products meet their label claims, often exposing significant failures in active ingredient levels.
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I just got my Conneqt and overall my results are good, but I was concerned about my low central pulse and blood pressure, so I came here to look around.
I took my first 20mg of telmisartan yesterday, and AI says that can be the cause. It seems it will take 48 hours for TM to be completely ineffective, so I’ll do this again in a couple of days to see if it’s related. (Too bad I was not smart enough to use this BEFORE taking TM!).
@cl-user I notice that your central bp/pp is also low. The report says we both have low risk. Does this mean it’s really no big deal? Or if I find TM is doing this, then I shouldn’t take it?
Here is my report based on two readings.
Something I don’t understand yet is the pulse pressure amplification. If you click on it, it’s the only section that does not open up your past results to see. You’ll see I had one result that was red and another green, but I can’t find the red number? It’s also the only section that doesn’t tell you what your results mean.
suppco
I installed on my phone and tried Add a product and I need to point the phones camera at a product bar code. What pill bottle has product bar codes on the bottle?? I have a half up todate 200 line spread sheet such an app needs to be able to digest!!!
Good idea re ratings, divulge any testing purity/ content info that exists. Ideally help with with interactions!!!
Any better app tips?
tnx curt
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I’ll add a few devices that I use and recommennd;
Grow muscle while siting, working from home, etc: kaatsu.com we bought 2 of the C4 to avoid arguments.
Pain / healing: LED device good for joints etc: kineon maybe kineon.com
Pain / healing; PEMF device: FlexPulse G2.
IMHO sore joints protocol; low inflammation diet devoid of the usual alergens, high in protein, high in colegen or suppliment with collegen, inject peptide BPC-157 and or the combo called GLOW or like me use KLOW 5mg/3x week near sore joint. Use the LED and PEMF device alternatingly daily.
Good luck, curt
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