Thank you for sharing your experience, and I’m happy it’s helped you with your transplant and other unintended but welcome benefits (in form of looking younger, staying healthy and benevolent side effects lol). I like your idea of 2-3 mg per week with the one-week break. I think I’ll do the same (higher dose to account for probably double the weight from you lol), so I plan 3+3 mg one week and then take one week rest. Will see what happens.
Thanks for saying I’m young but I’m not that young, closing in on 58. We have a saying back home which rimes “kryet gjok, mendjen zok”. Hard to translate word per word but basically means not so young in reality, but in their mind (meant as tongue in cheek) LOL
I think it’s correct to take weight into account. Mine is 110 lb only and rapamycin makes it very difficult to gain even a pound more. My goal is to gain 5 lb.
I do not take any other meds for immunosuppression. It’s the only prescribed medication, which is very rare, but is based on a very close match (blood type, antigens) of transplant to my body. There’s a small group of ppl among all transplant recipients who are naturally “tolerant” and don’t need any medication at all or a very small dose. I suspect that I may be one of them. I’m stable for a long time being on a small dose. I measure biomarkers once a month.
I don’t take 2-3 mg as one dose as ppl do for longevity. I take 0.5mg per day, so it takes 6 days to finish it. Such small amount taken gradually still accumulates and stays longer than a one time dose. Then I take a break. It really works well for me.
Bicep, if you want a detailed analysis of your blood cholesterol the link below may be of interest. LDL-C in general is a good but broad marker. Some parts of it are particularly bad, others not so much. This link is a sample analysis about the Labcorp “NMR LipoProfile® .” I believe Quest has a similar report. The test I had years ago did not have all of the nice explanations shown here and current tests may not either, but this visual aid is available online:
As others have said, there are many issues here. This is a comment on one issue in isolation of the interactions with others.
T2D is somewhat overdiagnosed. The typical threshold of diagnostic concern is an A1C level moving into the 5.7% to 6.4% range even though this level is far below the point at which cellular damage occurs. The medical community is not wrong in setting the threshold this low. Among people displaying these levels, especially those with high body fat and low muscle mass, many will progress to unhealthy levels if they do not make lifestyle changes, possibly including medication. On the other hand, if there is no progression to a higher level, there may be no risks if rapamycin is the cause of a mild elevation of A1C in a fit person. The gut biome plays a significant role here but that is a different topic.
Ivor does a really good job on insulin resistance and T2D. For the gold standard you check both insulin and glucose. If you’re cheap or in a hurry you can check at the 2 hour mark and probably get by with it. Checking glucose only doesn’t work because you don’t know how you got there.
A few months ago, a stress test showed that my stent was occluded. It’s in a small artery and the cardiologist wanted to put a new stent in. I told him that there is risk from that procedure and I don’t like the idea of someone poking around in my artery. I knew someone who died from that type of procedure. The cardiologist did some research and said there was a study with patients similar to me. They were followed for five years and the treated group had the same outcome as the untreated. So at least for now I’m leaving it as is.
12000 natto, alpha cyclodextrin, beta cyclodextrin(RemChol), and finally Chelation. That’s what I’m doing. If it’s plugging then there is a reason.
Just got back from my yearly checkup and after all the tests and putting my numbers into the formula he gave me a 3% of having a heart attack in the next 10 years. I thought he would have a stroke over my 400 CAC, but I guess that was old news. He was impressed with my HbA1c and I’m now pattern A. So maybe I’ll live after all. If he’s right, which I question.
Yup, box and a half so far. I’m getting a lot better at managing the whole thing and I think it is a very effective treatment. It gets rid of the worst offenders and leaves everything else alone. I think the reason I was pattern A was that the sLDL went down so far from previous years. I don’t have the papers in front of me because the nurse has to send them out and it takes her a few days.
It gets rid of inflammation by turning foam cells back into macrophages. This should do the trick. I’m sold on the medicine, just hate the delivery mechanism. I laughed so hard at the video rapadmin put in the humor section, and my wife couldn’t breathe either.
There’s no way I’ll go deaf, it takes too long and the doses are very small.
The alpha helps with LDL quite a bit too, it has to because I have the lowest LDL I’ve ever recorded and I used to use Rosuvastatin plus pcsk9 (for a month). I take it before each meal. I tried taking before and after and just trust me you don’t want to do that. It makes acarbose look like a walk in the park.
They should both prevent and cure. See the section I started on Chelation. The literature on this says outright that the metals in your blood cause a bunch of the trouble. So I’m doing both.
