Ah… we’ll get you to the dark side eventually 
Soon it will be all broccoli and lentils for every meal.
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Only six years? by my last count I’ve slowed my aging by 20, and I hope for much more hahaa
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What method did you use to count 20 year reduction?
The method of make believe 
but I do feel as healthy as ever, or as healthy as 15-20 years ago.
Another method I used is I approached a very attractive girl I thought she was in her late 20’s (actual age 33) and as we were talking, the age came up. Of course, I lied (big time) about my age. I said I’m 40 soon to be 41 and she didn’t question it. Needless to say we ended up together for a while but also needless to say it did not last that long (obviously, if you based your relationship on a lie it is bound to end pretty fast, I knew it though). so yes, I know I look younger than my age, but not by 20, more 5-7… however, I do feel as strong as I was 20 years ago, and my health is also the same.
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Ha-ha! It’s a great method! Keep working on it.
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Complements are important. They elevate our spirits. It’s also important imo to believe that you are young, strong, attractive, etc.
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Here in Hong Kong, everyone thinks I’m fat. When I travel back to the USA, everyone thinks I’m fit and healthy. Your frame of reference is indeed important.
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Regarding pantethine and policosanol for lipid-lowering, here is a summary from consumerlab, which does excellent and unbiased, fully-referenced reviews on many supplements:
(BTW that second column is titled “Evidence”, which for both is considered “inconsistent” by consumerlab)
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That’s pretty funny.
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It is rather suspicious, isn’t it? I saw zero before vs after effect on my LDL when I tried policosanol years ago. Maybe the Cubans spiked theirs with w/rosuvastatin.
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What is epigenetic‑based drug discovery platforms (from the cited paper)?
Cyclodextrin is amazing:
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming
https://sci-hub.se/10.1126/scitranslmed.aad6100
I did buy a box of RemChol. Very uncomfortable, I would say worse than DMSO or Niacin. Just not my cup of tea, but it will be interesting to see if it works, or if I go deaf.
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I think I’ll wait until Cyclarity releases their product…
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I’ll be right there too. In about 3 years if all goes well.
I think they gave the animals that went deaf 8gm/kg. So for me that would be 560 gm/day. I’ll be lucky to get 2 or 3 the way I’m doing it. I couldn’t find how to buy IV anywhere. There are a few places that would infuse it for me around here. Couldn’t buy. The polymerized form is much safer and I’m pretty sure that’s what they use.
That’s ok, my plaque was going down very slowly anyway. I just want it gone.
Summary:
- Low LDL does not affect your brain.
- Dietary sources of cholesterol do not increase blood cholesterol.
- Take Rosuvastatin and Ezetimibe to lower LDL
Rehashing the basics mostly.
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In the UK the threshold for concern about LDL-C is 3 mmol/L. On 15th Nov I did a blood test which reported 3.9 mmol/L. On 22nd Nov I did a blood test which reported 2.68 mmol/L.
I don’t fast for my blood tests. Hence they may be more variable. However, I do think labs should report how variable their results are as well as the range. If I did blood tests once a year and got 3.9 mmol/L I might do something.
Personally I am [edit to add] not entirely happy with what statins do although I would not try to discourage anyone from taking a statin. I have done in the past. However, in the last week my LDL-C dropped by about 33% and that was with me changing nothing.
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The threshold is too high too late, but I have no interest in arguing why since I have done so enough in this thread.
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RPC trials trump associations. Statins do not increase risk of dementia or alzheimers disease which means desmosterol levels may either not be significantly affected or may not matter as much.
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I don’t think those studies can rule out the association because there is so few patients that will get a desmosterol level low enough, have apoe4 allele, and have desmosterol levels supressed for long enough. But I am not overly concerned about it, I take a low dose statin with ezetimibe.
Good article I found: