Lesson, don’t sell adulterated product.
Either know/trust your source or get it tested.
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BREAKING:
Lilly is suing six distributors of #retatrutide Aesthetic Envy Cosmetic Centers Astra Legendary Peptides Striker Pharmacy Texas Peptides Lone Star Peptide Lilly said it has also referred more than 200 individuals and entities to the FDA, the U.S. Justice Department, state attorneys general, law enforcement agencies and professional licensing boards.
Lilly Press Release on this topic:
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Any updates on SLU-PP-915? I saw a video by bodybuilder/biohacker Youtuber Vigorous Steve stating he felt 915 to be approximately 5x as effective as 332. He was fairly adamant that 332 did have an effect despite knowing that the science states it is not orally bioavailable.
Timestamped link where he talks about it if you’re interested: https://www.youtube.com/live/qhGSBWOgJtk?si=TQ5qN9IGs0ryoSIV&t=366
We have demonstrated that an ERR pan-agonist (SLU-PP-915) with a distinct chemical scaffold from that of SLU-PP-332 displays similar exercise mimetic activity. Importantly, both of these compounds also induce a key gene that is a driver of the acute aerobic exercise transcriptional program, Ddit4 . SLU-PP-915 dose-dependently increases maximal exercise capacity, which is also correlated with the level of Ddit4 induction. Finally, SLU-PP-915 is the first ERR agonist shown to have oral bioavailability and demonstrated efficacy when administered orally. Such compounds may have wide utility in the treatment of a range of diseases where physical exercise improves the pathology.
Source: https://www.sciencedirect.com/science/article/pii/S0022356525403000
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I don’t know of any reliable source and the only evidence I’d trust is the study published by the SLU team. Not some gym bros opinion.
A application for a Phase 1 human trial is published.
It’s probably not hard to make but there are a few potential issues to be aware of.
slu-pp-915 capsules.pdf (606.8 KB)
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I think I’ve seen people brew it in suspension. The people who tried seemed to prefer 332, price was probably a factor.
SLU-PP (whether 332 or 915) are not peptides but rather small molecule experimental drugs. Discussing them in the “peptides” thread only serves to perpetuate this misunderstanding.
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I’m aware. I’m discussing it here because I searched for the compound and this was the only place I found it being discussed.
A thread on ERR modulators could be a good place to start.
I appreciate you bringing it up.
Even though SLU-PP-332 is NOT a peptide, it is commonly categorized as such and almost 99% of people that would dabble in ERR would be peptide users.
Thus, I believe it to be a valuable addition to this thread I started way back when.
Please continue to share any research you are doing with SLU-PP-332 etc and any results, affects etc.
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Last week, Eli Lilly filed six US lawsuits concerning the alleged unlawful sale of retatrutide.
It’s interesting that they are suing companies that apparently no one has heard of. Not sure what their strategy is, but it may in part depend on vendors who are careless in advertising and careless in their dealings with customers (providing email evidence for instance that they know customers are self-injecting the product, giving them customer support helping them do this, etc).
I don’t know, but I stocked up on reta months ago.
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That was my starting dose. I now dose around 1.2-1.5mg every 3 days. I was very sensitive to TA-1 initially but not anymore after using it for awhile.
The GLP-1–Mitochondria Axis in Metabolic Aging
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But loading up on NAD+ isn’t universally recommended.
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Neither is using Rapamycin, it’s a personal decision for now.
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Do you really think the majority of people using peptide care what the opinion/stance of the FDA is?
The FDA is really Failure, Deception, Abuse {as was coined 20 year ago].
This caught my eye today and I asked Perplexity if there is a peptide that would help.
Here is the result, some of our favorite peptides may be helping to mitigate sarcopenia.
any peptides that may help with sensory conduction.pdf (541.2 KB)
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Hopefully, some entity will find it in their interest to fund research.
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From its responses, perplexity seems to be assuming your question is directed at nerve injury from trauma rather than aging. I’d consider re-asking the question and specify nerve degeneration from the aging process.
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