Where is a good place to source raw peptides? I was interested in making capsules at home of pinealon and a few other things. I’m finding premade 1mg x60 pinealon capsules for $150-300, it is a ludicrous price I’m sure for what is 1mg + a few 100mg of flow agent/fillers in a capsule. Something I can easily do at home if I had the raw peptide powder.
China.
It took me years to establish relations with the suppliers I use. It cost me time and money to be where I am today. I doubt any peptide vendor is going to give up their supplier.
I’m also very skeptical of any Vladimir Khavinson research, due to who did the research, how it was “peer” reviewed and the journals it was published in. While very few peptides in the “hobby” have peer reviewed studies and even fewer with RCT.
I tried Epitalon for 6 months while stopping the use of NMN to see if the telomere support claim worked for me. I’ve had my telomere length measured by Trudiagnostic 5 times over 4 years and there was a trend indicating they were getting longer for the first 4 tests. They got shorter on the 5th test.
Some of the papers his group published.
https://orcid.org/0000-0001-7547-7725
A Perplexity review of he and his work. This AI remembers my research interests and threw GHK-cu in at the end to show an example of what a well validated peptide would look like.
Vladimir Khavinson russian peptide researcher, whe.pdf (457.7 KB)
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…they were getting longer for the first 4 tests. They got shorter on the 5th test.
What is your takeaway from that outcome?
To expand on @bluffsman 's question above, was NMN the culprit (good one) that resulted in telomere lengthening in first 4 test (to best of your knowledge) and was Epitalon the culprit (bad one) for the shortening of telomeres on your fifth test (best of your knowledge). Your message above is a bit murky.
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I’m not trying to compete with anyones business I want to make my own capsules to save money.
I think I meant lyophilized powder, not raw.
Just to be clear 
You can’t get lyophilized power out side of a vial. So you would be purchasing vials. There is probably a dozen or more selling “kits” 10 vials to a kit for decent prices. There are group buy groups on some chat apps that do that and send off a sample for testing.
Lyo adds a significant amount of filler (manitol) as part of the freeze drying process. Nothing wrong with that but you need to carefully weight it to be able to divide up the powder for encapsulation
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NMN works - as per my first 4 tests
Epitalon does not work - as per test #5
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I didn’t think you were, but I’m still not going to reveal my suppliers
My main supplier does not carry it. I will check next week with my secondary supplier.
If they have it, I’ll let you know a price but it will be raw powder, it’s the only format I carry.
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Thank you.
And that is a N-1 result. Not terribly reliable for general application as I may be an outlier, if I was part of a RCT with many participants.
@Steve_Combi, I was interested in knowing if you think that NMN lengthens telomeres, and do you think that Epitalon shortens telomeres?
I don’t think anyone, myself included disputed the connection of telomere length and longevity.
A more important point (to me at least) would be, which substances/supplement are believed to lengthen them and which ones shorten them.
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Thanks mate!
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Sorry that was not directed to you I meant to use my own quote as a follow up.
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I know that many people don’t think this type of measurement is important, here is a study that indicates it is. Telomere length is a strong indicator of mortality.
The question remains, in healthy people is there a long term benefit in reducing mortality risk using interventions of any kind to maintain telomere length?
In conclusion, shorter age-adjusted LTL was associated with long-term mortality in hospitalized older adults and interacted with frailty, with its prognostic value being evident in individuals without frailty but attenuated in those with established frailty. These findings support the potential relevance of telomere length as a biomarker of biological heterogeneity and vulnerability in late life and highlight the importance of integrating molecular aging markers with the assessment of clinical geriatric constructs. Future studies should investigate whether combining telomere-based measures with multidimensional frailty assessments can improve prognostic accuracy and inform personalized approaches to care in older populations.
The grey market may live on…
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Correct decision for each of these, as there are no phase 3 (or even phase 2) data behind them.
Peptides that have phase 3 data behind them, like HGH, SS-31, GLP1s are another matter entirely.
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Ipamorelin + CJC 1295 noDAC
400mcg + 250mcg
5 nights a week, Sun - Thu - with short breaks (1 week) every 3 or 4 months for 3 years.
That has been my hGH stimulating program for an extended period of time. About 2 months ago I took a 6 week break. Not intentional, more out of laziness
You know, the mechanic that doesn’t have time to fix his own car LoL!
When I started using the Renpho Morpho 8 lead scale a few months ago, I posted on my VAT (visceral adipose tissue) number as being 3 - this is not accurate compared to DEXA and CT but it will show a trend.
Without any other changes to my routine, in about a week my VAT increased to 4, I didn’t think much of that, still pretty low. But trending up so it got my attention. No change in my body weight, still 144 - 146 on a daily basis, for the past 2 years. I was a bit puzzled.
Two weeks into my abstinence, I noticed my sleep was not as consistent, with more waking up (4 to 5 times a night) and harder to get back to sleep. This is very unusual for me, my typical is 1 or 2 times a night and immediately going back to sleep. I thought maybe I’m experiencing what many do as they age, crappy sleep.
Didn’t like it. Even upped my dose of DSIP but it didn’t make a difference in the waking up thing, but the higher dose did bump my Delta sleep to a higher number, so this is now my new nightly dose 600mcg. Would not have found that without this “encouragement” to fix my newly poor sleep.
Three weeks in I was noticing more pain in my left hand, the one with a bit of arthritis. This was more annoying than the other 2 as it was all day long.
I didn’t immediately connect those changes to the Ipa+CJC program but I know that hGH has a positive effect on those 3 items. So I decided to dance with the one that brung me
We restarted our IPA+CJC nightly routine again, now at 8 “on” nights 5 + 3
Within the first 8 “on” nights, all back to “normal”, sleep is good again, VAT went back down to 3 after 5+2 nights and my arthric pain is significantly diminished and back to pre-break.
The interesting thing to me is how quickly the benefits diminished and how quickly they came back.
We all adapt to our new normal, when annoying things go away. We typically don’t dwell on past pain and suffering, we start living life doing the things we enjoy doing and some of things we didn’t enjoy LoL!
As the saying goes, you don’t know what you’ve got until it’s gone.
Almost forgot HAPPY CANADA DAY!!
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Thanks for this.
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Is Canada still a country? Oh, I forgot Happy Canada day LOL
We will be a country long after the US empire falls like all empires do. Just ask Ray Dalio
Interestingly for every empire that has fallen, the world goes on and new empires arise. I figure it will China’s turn to give the empire thing a go…
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