So, a little background; I’ve been longevity supplementing for 3-4 years and I travel a lot. My current stack is as follows:
Novos (fisetin, magnesium. glycine, glucosamine sulfate, pterostilbene, hyaluronic acid, rhodiola rosea, l theanine, micro dosed lithium, vitamin c, malate, ginger, calcium alpha-ketoglutarate).
donotage sirt 6 activator
liposomal nmn/liposomal apigenin
ginger with high gingerol
krill oil with astaxanthin
melatonin 10 g
maybe 1 or 2 things I am forgetting
up until I started taking my prescription meds, my immune system was quite robust with how I supplemented, and I rarely got sick at home or traveling and can’t recall a food poisoning traveling while supplementing with these types of items without the prescription meds
while reading about some of the life extension of some prescription meds I added to this
Rapamycin 8 mg weekly (I unfortunately took it daily for one stretch of time, but mostly once weekly)
simvastatin 20/10ezetimibe (simvastatin 40 with no ezetimibe for a stretch)
I’ve been taking these meds for 4-5 months. I’ve caught a few colds, and I’ve now caught food poisoning 4 times over the last 7 weeks of travel, whereas I rarely caught it prior to introducing these prescription meds. All be it, two of the food poisonings came when I was taking the rapamycin daily. But while taking it weekly, twice in the last 3 weeks.
Some rookie speculation:
is my mtor being overly shut with the rapamycin AND how I supplement?
does high dose statin use cause immune problems and its being added to maybe with rapa and other elements?
are the statins and rapamycin or other things I take not playing nicely together? Switching to another statin may be of benefit?
Is it dangerous having a low immune system? I think I could take the intermittent sickness otherwise.