mTORC1 regulates a lysosome-dependent adaptive shift in intracellular lipid species

#1

Finally an answer as to why rapamycin raises triglycerides?

https://www.nature.com/articles/s42255-022-00706-6

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#2

Nice! The question is…does this metabolic flux eventually settle down and if not, is it mitigated by the other effects of mTOR inhibition in terms of risk?