I think Maraviroc renders senescent cells useless as in “puts them to sleep” as opposed to clearing them out. At least that’s what I read in one of the posted studies. But once they’re inactive and unable to do monkey business within us then probably that’s same effect as removing them.
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You’re taking a quarter pill with dinner every night? What dosing frequency are you using.
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Once I land on a dosing protocol I’m going to start the regimen and report back. My workouts, supplements, macronutrient intake, TRT, etc are all very consistent and have been for years. I will not alter them or introduce any new cofounders into my routine in order to get a clear idea of any perceived efficacy of the drug. I got 60 150mg tablets from India.
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I don’t know I understand your question exactly, but if it is about dosing in mgs it is 1/4th of 150mg every day with my dinner meal, basically about 37mgs per day. I have not made my mind yet as to how long I want to do it for. Apparently aids people take it for life with little or no negative effects, so for now I’m in the wait and see mood. If positives continue as I think they are now, I might decide to stay on it for a very long time. Initially, my intention was to do it for 3 months and maybe repeat it annually.
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My question was based on you suggesting that you are taking it EVERY DAY. Did you read through all of the data in the posts in this thread? The consensus is that the doses should be pulsed (as infrequently as twice a week) for this application (IE: not HIV) so that the medication is cleared out of the system entirely before the next dose. What was the basis for you deciding to take it everyday?
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Oh, I see now. Actually, I have an auto immune issue and from what I can tell Maraviroc seems to have a great positive effect on it, to the point of fixing it completely so that’s why I decided on the daily dose. So, basically, I’m a bit of a unique case which may not be a good example for everyone.
BTW, since the dosing is relatively low, (compared to what AD’s people take daily) I’m actually contemplating going to twice per day (37X2) but as I said my case is somewhat unique. From what I’ve heard there seems to be an issue with immune system because of it, but I’m keeping an eye in case I see any symptoms. Otherwise, I’ve had no negative side effects.
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Got it, makes sense now. At the end of the day we’re all self experimenters here so keep us posted!
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Or if you grind several at a time, use a coffee grinder…
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Which autoimmune syndrome are you treating with Maraviroc, please?
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I never got properly diagnosed but certain substances or foods/drinks trigger inflammation which results in having joint pain and swelling (to some degree). I have to be honest that initially it seemed that Maraviroc was a godsent for such immune issue but as is the case with all new substances I’ve used the positive effects tend to taper off after a while. I am still using it, and I still like it though. I might play/change the dosing and frequency though.
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Just saw my Physician this morning… damn he is amazing.
Started me on TRT cypionate 6 years ago…rapamycin 5 years ago…HGH 1 year ago.
And just prescribed Maraviroc… 75 mg … every 2 days.
Showed him the research.
Article: HIV Drug (Maraviroc) Reverses Muscle Aging by purging Zombie Cell Signals
He knows it’s safe as he has prescribed for HIV patients with no issues.
My dose is based on translational protocol.
Cost will be about $100 per month.
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Sorry to nickel and dime this, but I’m never clear what every two days really means (English is my second language). Is it every other day, or is it Monday, then Thursday and then Sunday (as an example)? I ask because I’ve been taking it but have not settled myself on a continues dose yet.
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Can take all at once 75mg then skip a day… so every other day.
Or split pill take 32 mg per day.
We discused the various pill options.
As it is not the 300 mg daily x 2 so a total of 600 mg is HIV dose.
Taking it all at once 75 mg and skip a day… or 32 mg every day… should be no problem.
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Thank for explanation. I’ve been doing 32.5 daily for almost a month now, and I really like the results. My muscles are loving it as in I can tell I am stronger (beyond any possible placebo effect). Also, my muscles feel firmer to the touch.
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Damn!
Sounds great. I have plateaued on muscles and weight sets for about 2 years. Will be real easy to see if I get that 28% increase in size… and increased weight load and number in my sets.
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I’m more interested in strength… let us know how it impacts your lifting (kg) measures over the coming months. Track it, for your reps, if you can. Would be very interesting.
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Don’t know about the 28% but I’m almost certain you’ll reap real measurable positivize results. Circle back in a month or so and let us know how things are going. I am actually very intrigued by this drug, more so than any other substance I’ve come across in a while. If we get anywhere near 50% of stated results, I’d be very happy.
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It would be really interesting to seem if there are measurable results. For example, if you usually do 10 reps at 100lbs for a given weight-bearing exercise, perhaps it increases to 10 @ 120lbs. Any way you can measure it would be more helpful for all of us here, and help to remove the placebo effect.
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Clearly @Agetron would be better at getting real measurable data as I’m not much of a gym person but what I can tell is the fact that for last couple years I do 3 sets of 25 daily pushups. And sometimes I’d push myself to do the max number and the most I got in last year or so was 31. I tried this morning (after doing Maraviroc for over three weeks, and nothing else on my regimen was new) and I could easily do 30 pushups. I pushed myself on the last set and actually I managed 36. I know 100% that I have not been able to do 36 in last five years.
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Yes.
By plateaued in size… I meant to include weight sets too. They go in tandem for me. I have maxed myself out. No weight increases in a year.
When I started rapamycin…I was increasing weights in all machines 10 to 15 pounds every 3 to 4 months. Finally peaked.
So I can hit 190 lbs. chest flies… 30 in a set. Stuck can’t go higher right now. If I were to hit 200 lbs. That would be significant. 175 lat pull downs… 30 in a set. 180 or 185. Big move.
Pull ups 20 per set. Go to 30 would be fantastic.
If these 3 areas alone increase in weight or number… it is significant for me.
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