I’m new here and there is so very much good information I’m finding it a challenge to read just half of it.
I wondered if there was info relating to how quickly Rapa works to reduce body age. Eg - does taking Rapa for 6 months at a standard 6mg/week dose reduce biological age by 3 years…or taking it for one year result in a 5 year reduction.
There are quite a few people who keep really good stats about their health status. I wondered if there was some kind of general view on the efficacy ratio of Rapa.
I’m interested to see what responses you get to this. It will be a variety. I can’t give you an answer. You asking for a simple answer to a very complex system.
First, I have no faith in “age clocks” so there’s no way to measure the effect.
Second, the reasons people take Rapa are various and give various results. For those hoping to live longer, then only waiting 30-70 years will tell us. Many just feel better. Hard to quantify that.
I had been working out for past 7 years… no real gains… then started TRT injection… 1 time weekly… 4 years ago and BAM…
I really bulked up! … 200 mg as 1 ml.of cypionate helped turn fat into muscle.
The rapamycin then acted as a shredding… so muscled, strong and lean.
I take rapamycin then TRT 3 days later… so they balance catabolic - clean and anabolic - grow.
For the other “old” people here, does anyone notice “withdrawal” symptoms when they stop Rapamycin? You wake up one morning and notice everything hurts again?
I am 72 and I started rapamycin 4 years ago.
After starting at 4mg, I have been taking 10mg a week.
Observations:
My mouth health as improved
My weight has gone up which is bad.(I am the sole caregiver for my ill wife. I lose a lot of sleep. She is in the hospital frequently- is now as I write this note - and I stay with her in the hospital- 80 days since last August)
no joint pain before Rapa and still no joint pain since
-All blood tests are normal except free testosterone is low and TSH is high.
-Blood pressure is 110/60
-I take many supplements and several drugs(from India pharmacy so not doctor supervised)
drugs include a statin, daily 5mg generic Cialis, acarbose and Canagliflozin
supplements include several medicinal mushroom extracts, glucosamine, taurine, creatine, hyaluronic acid, lithium, Ergothioneine,
Urolithin A, Ca-Akg, collagen peptides, and Astaxthin as the most important supplements plus many of less importance.
Yes - I’ve had this when I paused rapamycin due to the plasmapheresis trial I participated in. It took a month or so to happen, but perhaps part of the issue on why I felt worse doing plasmapheresis than I had felt on rapamycin for the past 3+ years.
On 6mg a week. Blood tests (every three months through Agelessrx.com) have shown a biological age drop from 54 to 48. I’m 56 years old. All inflammation gone from my body.
You are a similar age to me so I thought I would chime in. I have been on rapa for 18 months and currently pulse 6mg once a week for 6 weeks with 2 weeks off. I started at 2mg with a 4 week on and off pulse.
I have not seen any difference in how I feel nor in my blood work but I have just increased my exercise routine to fit Attia’s protocol, started metformin and now Repatha so I’m not a best test case but I thought I would answer.
