I’ve just been prescribed Flomax and 5mg finasteride for my enlarged prostate. It is 52cc and I’ve had a TURP some years ago. Ypu seem to do okay on it.
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We all have a very individual biological construction. For me, taurine can provide both daytime energy and nighttime relaxation/sleep. I take it for energy as well as to improve sleep during the night.
When I wake up during the night, I take 2-3 grams of taurine and it is a reliable way for me to slowly go back to sleep. When I take 5-7 grams of taurine in the morning, then after 90-120 minutes, I get a rather long-lasting boost of energy. I have tried to find an answer to these bi-directional, context-dependent physiological effects. For me, taurine is a mild energizer during the day and a relaxant/sleep aid at night. ChatGPT has given me a few clues:
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GABAergic & Glycinergic modulation: Taurine acts as an agonist at GABA and glycine receptors, which has calming, sleep-promoting effects.
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Glutamatergic balance: Taurine can also inhibit overactive glutamate transmission and reduce NMDA receptor excitotoxicity, stabilizing neural activity. which can improve sleep quality but also sharpen daytime mental clarity.
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Mitochondrial & Cellular Energy Effects: Taurine conjugates with mitochondrial tRNA and supports efficient oxidative phosphorylation. During the day, when energy demand is high, taurine supports mitochondrial ATP production and neural firing stability, which can be perceived as a steady “clean” energy boost after 90–120 minutes (time for absorption and mitochondrial integration).
Thank you for sharing. BTW I tried C60 a few years ago and I am curious to hear about your observations.
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Yes I do.
Pretty much have taken 5 mg nightly… for 33 years or more. Started with proscar…for my hair retention then, went on generic finasteride. Never had any ED issues. Started tadalafil about 4 years ago… to open and relax all veins. Libido and ability great… typically get off morning and night.
As a long term user of finasteride, my prostate remains walnut size… is a prostate cancer prevention medication, clears cholesterol from the blood, and yeah still have my hair… going on 68 years.
Updated my avatar this week… just incase anyone noticed. 
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Nandrolone decaonate and I haven’t had any of those issues at 200mg or less
75mg-100mg is probably the good safe amount for indefinite use but that’s an educated guess form doing a deep dive on it. 150mg could be safe too but I think the joint benefits are the same at 100mg. Of course no one who isn’t on TRT should consider this.
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Bempedoic Acid
180 mg evenings
Creatine HCL
1.5 g evenings
Dapagliflozin
5 mg mornings
Ezetimibe
10 mg evenings
Life Extension 2-Per-Day Multivitamin
1 capsule evenings
L-Theanine
200 mg mornings & evenings
Magnesium Malate
113 mg mornings
Evolocumab (Repatha)
140 mg injection bi-weekly
Retatrutide
3 mg injection split weekly
Tadalafil
2.5 mg 30 min-2 hrs before exercise
Taurine
2 g (split 1 g morning / 1 g evening)
Tazarotene Gel 0.05%
Pea-sized EON
Vitamin D3 + K2
10,000 IU / 200 mcg (Adjusted to 50 ng/ml goal)
Viva Naturals Triple-Strength Omega-3 Fish Oil
2 capsules evenings (~1,500 mg EPA, ~310 mg DHA)
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That’s what I do for a few weeks now (tendinopathy). I dissolve the collagen in a black coffee, it does not taste anything and gives me some caffeine before training.
30g Peptan collagen, 480mg vitamin from BerryPlus, and 20mg tadalafil.
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This seems closely related to Dr. Keith Barr’s work. I stumbled on a reference in a post here on RN. Barr’s field of study examines how tendon, ligaments and joints can recover from injury, using isometric holds. He is also a molecular specialist and this where collagen (gelatin) and vit c comes in. I used his approach to deal with knee pain and calf injuries. And it worked well beyond my expectations. I used the vit c / collagen dosing prior to doing the isometric rehab work, but expanded the dosing to other activities like strength training, skiing, and sprints. It just seems logical. I highly recommend Barr’s field of study if you want to bullet proof your active joints.
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Mine changed a bit!
Meds:
Morning
- T4/T3 100/20 upon waking, empty stomach
- Modafinil 200mg
- Empagliflozine 25mg
- Eplerenone 50mg
- Bempedoic acid/ezetimibe 180/10mg
- Raloxifene 60mg
- Tadalafil 20mg
- Mirabegron 50mg
- Salbutamol 4mg
- Telmisartan 80mg
- Ivabradine 7.5mg
- Desloratadine 5mg
- Testosterone, boldenone, trenbolone 175/40/20mg
- DHT cream (Andractim) on scrotum, 5g
- Oxymetholone 50mg
- Retatrutide 1mg once a week
- UDCA 250mg
Pre-workout:
- Oxymetholone 50mg
Before sleep:
- Trazodone 100mg
- Pregabaline 50mg
- Ivabradine 7.5mg
- BPC157, TB500, GHK-Cu 0.5/0.5/5mg
- Melanotan II 1mg
- Growth hormone 4UI
- UDCA 250mg
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Of the last two stacks posted, one takes Ezetimibe in the morning, and the other takes it in the evening.
Is there a best time to take it or doesn’t it matter?
From what I see on the internet the evening is favoured as the body supposedly makes more cholesterol at night.
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A 22 hour half life and a non-linear dose response means it doesn’t matter at what time you take it.
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That’s full on how do you feel on that? I just started topical DHT it feels good.
I feel great. Really better mood and more motivated.
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I bet lol. What got you.to add trenbolone in?
Bodybuilding cycle, the quantity are per day.
At low dose (140mg weekly) I do not have any physical sides effects and trenbolone works mostly as a SARM in the muscle with high anabolic property. There is also a beneficial blockage of the GR and MR lowering hugely the muscle catabolism.
Boldenone is here to lower estradiol level to a physiological level
Testosterone to build muscle, same for oxymetholone.
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What benefits are you finding from exogenous DHT? I started recently and it has improved sexual function dramatically, and has improved general confidence.
Wow.
I’ve wondered what a subQ micro dose of trenbolone might do.
Mostly the same as you. I got gyno surgery three weeks ago, I don’t want it to come back.
I’m less bloated with DHT, I look leaner.
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It’s so good. Experiencing it settles the argument for me that DHT isn’t a “trash hormone”, it just feels so damn good. A lot of men need it to fully optimize their hormone replacement therapy. Now if we could just fix the negative effects on the hair and prostate we have something really powerful.
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This is a serious bodybuilding cycle, this adds up to 1645mg injectable and 700mg oral androgens weekly if I am correct? How long do you plan to run this?
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Yes indeed. I started muscle building again after a really big weight loss from 80kg fat to 58.5kg in mid-January. I’m now at 84kg, lean, but not shredded.
I’m blasting back, I planned 16-20 weeks but if weight is still going up I can continue -or stop before it’s no longer qualitative (fat gain>muscle gain)-
Same for oxymetholone, it’s not that liver toxic, it is used up to 6months to a year in modern medicine without any real issues, and I take liver protection (NAC, glycine, UDCA, sylimarine).
Biomarkers are great, HDL-C is lower for sure but ApoB was at 27 last time I checked. BP under control, and echodoppler+ EKG perfect.
Of course longevity take a hit -maybe not that much ?-, but I take precautions.
I like that, so if I can combine both, I do so.
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