The paper was posted earlier: Cardiovascular Health 2024 - #2440
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Haven’t looked into it, but perhaps these threads with paper links are helpful (multi part series):
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Really interesting, thank you.
Love the table of data. ApoBs in the 75 to 85 range. But the thread convincingly argues for the impact of high energy expenditure on CVD
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Get the LDL-C down and keep it down…
Time in LDL cholesterol target range and major adverse cardiovascular events risk: A pooled analysis of two cohorts
Background
Traditional management of low-density lipoprotein cholesterol (LDL-C) relies on single-point measurements, neglecting long-term magnitude and the duration of exposure to elevated LDL-C over time. This study aimed to evaluate the association between LDL-C time in target range (TTR) and the risk of major adverse cardiovascular events (MACE) in two US cohorts.
Conclusions
LDL-C TTR independently predicts MACE and may offer a more comprehensive assessment of long-term LDL-C control than mean levels or variability, supporting its potential clinical utility.
Open access paper:
https://www.sciencedirect.com/science/article/pii/S2666667725003654
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Good article.
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