I am inspired by the improvements some have had in tinnitus and allergies. Those have been my two of my most annoying health problems.
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Really interesting. I also have had complete cessation of my my usual allergies during the spring/ pollen season once I started rapamycin.
I really started getting bad allergies (sneezing, runny nose, etc) in my mid-20s, and it continued for the next 30+ years until I started taking rapamycin, and then the issue went away entirely. When I’ve paused rapamycin for any length of time during the spring season, my allergies have come back.
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Allergy cessation is a new angle that would appeal to a large audience.
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I can vouch for the allergies being cured. Starting about age 50, I was getting allergies that I never had before in my youth… from Cedar in spring and Ragweed in the fall.
This is continue with needing a lot of flonase (was a prescription only when I first used it) used at the beginning of spring and in early fall…until a hard freeze.
Now, 3 years straight, using rapamycin have no allergies at all, so it has pretty much cleared that…taking me back to my pre-50’s resistance to allergies.
My sinuses are more moist and full now too.
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While we’re hearing some good results with rapamycin use for women who are potentially seeing a reversal of menopause as reported above, and in this thread: Women Taking Rapamycin for Enhanced Fertility / Menopause Prevention?
But, we are also seeing situations that suggest males may also receive benefit in fertility from rapamycin:
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from our forums:
and another:
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Rapamycin seems also to be helpful for people with Lupus (we’ve heard from multiple reports in our discussion forums):
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Seen today in the Facebook Rapamycin user group. I concur with the sleep benefits - I see similar results.
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In the category of “Other types of benefits from rapamycin” - in this case epilepsy and autism:
Source: x.com
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Rapamycin for Arthritis:
For example, I have hand arthritis that had worsened over the last year. My PCP examined my hands and understood the extent of the problem. I summarized the lit on rapamycin and arthritis. My PCP proposed an experiment. She gave me the low-dose prescription I requested and we set up an appointment (and blood labs) leaving about 14 weeks for the rapamycin to show an effect. We were both astonished at the next appointment—my arthritis pain was greatly reduced and my range of joint motion increased a lot. This is a real quality of life difference for me—there are no effective approved meds for osteoarthritis.
Source: Rapamycin Prescription, Doctors that Prescribe It - #166 by Powe
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Here is an interesting piece of data. I started rapamycin 5 years ago 12/2019 and have been taking either 6 mg weekly or 10 mg every 10 days since. Traveled south for a 30 day vacation in Dec but forgot to bring my rapamycin - so for the first time in 5 years I went without it. Since BJohnson stated that rapamycin negatively effects health I figured I’d get my annual blood work done before I resumed.
One (2 but related) results popped out. Had 5 years of data with poor kidney function out of range results. During 5 years all results were in range and suddenly I am back to 5 years ago
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What about Cystatin-C. Creatinine is strongly influenced by muscle mass.
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yes, I will test this next time
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I have been taking 6mg a week for about a year through ageless Rx. I have lost some weight, but no real noticeable benefits. There was a mix up one month in my rapa delivery, so i wound up taking a week off and had noticeable weight loss the following week once i started rapa again. i was wondering who is providing the rapa to you that recommended 12mg once per week?
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Many of us here are just buying rapamycin from other locations (e.g. India: How to Get Rapamycin, Where to get a Prescription ) and testing different dosing levels. There is no really good data on what the optimal dosing level is for human longevity, so people test different doses and do blood tests to see if there are any negative effects of higher dosing. In many animal studies, higher doses result in greater longevity benefits (but there are risks, such as immune suppression, when you go to high regular dosing).
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No one recommends a dosage level.
All of us just making the best educated guesses we can.
I’ve dialed into 20 mg once every 2 weeks (with healthy fats).
Probably reasonable to increase your dose until you experience something negative, then back off a little.
I could take more or begin taking it with grapefruit juice.
I’ve never experienced any side effects.
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