Aging Doesn't Cause ASCVD, Hypertension, Diabetes, etc

[A_User]

Data from this review strengthen the concept that HBP is not consubstantially linked to aging but instead to the unhealthy lifestyle that most of the modern, westernized world population has adopted.

Optimal Blood Pressure we Should Target? Systolic Under 110 or 100?

I was familiar with only the Yanomami but here’s a review of other hunter-gatherers in South/Central America, all had 95/65 BP with hypertension (>140) at 0-2% prevalence. [image] African hunter-gatherers data ~120/80 hypertension 0-2% (Hadza higher with age): [image] Asian fish-hunter-gatherers: [image]

HBP causes a lot of other diseases as well.

The case for ASCVD is in this thread (separate from HBP):

Apolipoprotein B (ApoB)

There are no biomarkers in an otherwise healthy individual to be lowered that is as powerful as apoB to prevent health decline and increase longevity. I think I have summarized the most important of the current information in this thread, if I missed anything you can post it here. ApoB is the Rate-Limiting Step in prevention of cardiovascular disease, which is the primary cause of death in the U.S. and across the world. The leading cause of death today, with 17.9 million deaths yearly, 1 in 5 people die from it (1). Although a multi-factorial process, it can be controlled and prevented by this single factor. There are untold amounts of people who survive their heart attack or stroke but are maimed for life with diminished quality of life. As such, even though reducing apoB improves lifespan, preventing heart attacks and strokes are worthy in of itself especially if the prevention strategy has a proven net benefit by reducing all-cause mortality. The importance of apoB comes from the…

[A_User]

The title of this thread is slightly clickbait, the real one is

"Aging Doesn’t Cause ASCVD, Hypertension, Diabetes, etc, within the normal lifespan",

so the veins/arteries, pancreas, etc, are aging for sure. But the salient disease most are familiar with is not aging related but lack of early risk factor control. So it would be confusing I think to the public that lifestyle/risk factor disease are mentioned to be caused by aging by showing an age related graph when this salient disease IS time and exposure. Disease in centenarians/supercentarians and cap on maximum lifespan is different.