With my recent labs on 5/3, my biological age using this Levine formula is 35.31 years. I will turn 58 on June 12th. (so, a 21 year biological age reduction from chronological age)
I have taken rapamycin for 1.5 years and currently on 20 mg every two weeks dose. Unfortunately, I did not do this calculation before I started rapamycin. This is the first time I did the calculation (after my 5/3 labs).
Whatever you’re doing, that’s an impressive youthing result.
Mind sharing your last phenoage full panel, curious to see what marker(s) might have been associated with the large reduction?
Mac. Not sure what you are asking. I have not had CR protein checked for years so really can’t compare to previous indices to put in Levine calculator. I will now get full CMP, CBC and CRP in all future labs to do calculation.
When you say Levine formula, are you referring to the widely reported here phenoage? See EnerQay spreadsheet above.
Do you have a similar spreadsheet showing the markers that yielded your 35.3 biological age?
I used the spreadsheet that Rap Admin posted on another thread.
Initial post in this thread that includes link to Levine Phenotypic calculations spreadsheet - click here.
Here is the spreadsheet with my numbers…
Neck_Bio_Age_May22Labs.xls - Compatibility Mode.pdf (29.0 KB)
Looks like your glucose, Lymphocytes %, Mean Cell Volume, RBC Distribution Width are low, driving down phenoage.
hbA1c, lipids, other liver/kidney function markers?
from same 5/3 labs:
Alkaline Phosphatase: 73 (range: 44-121)
AST (SGOT): 28 (range: 0-40)
ALT (SGPT): 31 (range: 0-44)
Cholesterol, Total: 166 (range: 100-199)
Triglycerides: 53 (Range: 0-149)
HDL: 66 (range: greater than 39)
VLDL Cholesterol Cal: 11 (range: 5-40)
LDL Cholesterol Cal (NIH): 89 (range 0-99)
Thoughts?
I’m envious of your cholesterol levels 
RapAdmin. Those actually were up a few points since labs in Feb. HA! Wish I would have done CRP measure in Feb and in past so I could trace biological age over time. Will do that from now on. My diet is very strict as well. No meat of any kind, no dairy, nothing fried…so I’m sure that helps cholesterol. My 23 and me genetic testing says I am predisposed to very high cholesterol and fatty liver disease so I think lifestyle and supplementation helping counteract genetics. I appreciate you and MAC’s input on my numbers.
Can you give me an idea of what your diet looks like typically… breakfast, lunch and dinner?
Excellent looking lipid and hbA1c markers.
Your TG of 53, and your TG/HDL is 0.8 (<1 is excellent), and your remnant cholesterol (TC-LDL-HDL) is 11 (very low CVD risk quartile).
You have GGT, eGFR liver markers?
On diet, you were on this diet BEFORE Rapamycin?
Yes, please do share your diet.
MAC, thank you for the input on my labs. Very helpful. I just have the liver markers on basic CMP. Do not see a GGT but eGFR is 107 (range: greater than 59). Would GGT be on CMP under another name?
Diet: Stop eating meet of any kind 15 years ago. Stop eating any sugar 5 years ago. Been on Rapamycin for 1.5 years. Fairly low carb diet. Nothing fried. Protein comes from beans and nuts mostly. Eat a lot of whole grains and produce. Very little dairy. When I go to store, cashier thinks I have rabbits at my house given vegetables I buy. I only eat when hungry and don’t eat by the clock. Most eating occurs in 4 hour window in late afternoon early evening. I used to fast a lot (24 to 48 hours water only a few times a month) but don’t have the desire or toughness to do that much over past year. I do have a vice. Drink a lot of Sprite Zero. Used to be an ultramarathoner up until age 50. Longest run was a 50 miler. Ran over 50 marathons. But since 50, lost that desire. Try to get 30 min of brisk walking/jogging most days of the week but not too much more than that. Let me know if you havehave any questions. Thanks for your interest.
Also, my diet is very low in fat due to what I normally eat…eat more carbs than fat but try not to overdo it with carbs in whole grains. Really like whole grain breads and related. I’m 6 foot, 145 lbs so fairly lean.
eGFR is 107, amazing level.
GGT is liver enzyme marker
Your previously posted markers, including your phenoage, are consistent with your diet.
Your BMI?
What triggered Rapamycin intervention?
Have you ever done a CT coronary calcium scan of your heart…between your running history and diet and markers, would expect low indication of CVD.
MAC,
Thanks for info on GFR and GGT. I will get GGT measured next labs.
BMI is 19.7.
Indeed, I did a CT coronary Calcium Scan of my heart a month or so ago just for benchmark for future. Results said I had a calcium score of 25. So not ideal according to my readings. Thinking of starting 5mg of Crestor to help in this area.
Full report follows. Thoughts?
Doc8.pdf (78.5 KB)
Forgot to add. Started Rapamycin given I wanted to be proactive in terms of longevity instead of waiting for some major malady to happen and doing something about it then.
@AlexKChen Alex - can you post your full lab results sometime for the Levine Phenotypic age calculations. Given your Levine calculations putting you at that of an 11 year old, you’re one of the few other people who are bumping close to this 21 year reduction of biological age compared to chronological age.
