Also it may not reduce in a manner similar to the decay of a radioactive particle in the sense that there is not just an exponential curve, but something more complex.
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That is kind of arbitrary, but considering that kidney transplant patients usually aim for levels of 5-10 ng/mL I would say at least ten times lower than that.
True, but the important point is that your through level will reach steady state after about 5 half-lives regardless of whether you take it every two weeks, or weekly or even daily. That’s why you have to measure after at least 5 half-lives, because only then will you know what your through level will really be when continuing to take rapamycin regularly.
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