Beetroot is reportedy high in Nitrate. I quite like Pickled beetroot as something to eat which has a relatively low calorific content. I am not deliberately increasing my Nitrate intake, but I recognise that this has an effect.
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These are the ingredients in the NO supplements I take to get a NO boost in the AM (nitrates in the body donât seem to last more than 12 hours). I eat celery at dinner. Potassium nitrate is one of the ingredients. Make sure you are getting a pharma grade or food grade quality.
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Well, it always makes me nervous when they admit they donât know whatâs going on in the first sentence:
Of course Nitrate makes your pasture grow like crazy, but is well known to be dangerous:
https://extensionpublications.unl.edu/assets/html/g1779/build/g1779.htm
And I remember back during the mad cow scare when alternative publications were saying it was due to using commercial fertilizer and they had correlated and had labs done and their story looked possible to me. I certainly donât know. I think Joe has a very conservative plan that looks safe. Safe is good. Good luck,
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I have come down with a mild case of shingles now which has turned everything I was doing on its head. I am not even game to go to the gym now until I am fully better. Not much pain but really tired and lots of tummy upset. I am hardly taking anything except MB and lysine.
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@Joseph_Lavelle
@Bicep
@ anyone using MB and NO
I watched the above video that was originally posted somewhere by @desertshores Itâs good information that Iâve been looking for, for awhile. Does anyone know much about dosing MB along with NO boosters that actually work as proven by saliva test such as the Berkeley Life product Joseph Lavelle introduced us to?
I read the book âUltimate guide to methylene blueâ by Marc Sloan. While Sloan did talk about dosing of MB. But he also emphasized what a bad thing NO is to the mind and body. In general he thinks NO is bad. He lost credibility in my mind at that point. So, at one point I was taking MB. I rarely feel anything from supplements but I definitely had a sense of wellbeing from MB. Unfortunately I quickly developed a tolerance so I quit taking it. Now I am taking the NO supplement from Berkeley. I like that I can use saliva test sticks to measure NO. And it actually shows measurable results unlike any other NO booster Iâve taken before such as beet root, l-arginine, l-citrulline, and HumanN NEO-40.
So, now that I have an NO product that works I like the idea of revisiting MB. Does anyone have any tips for dosing and timing and frequency of these? As in, do you take them at the same time or apart? Would it make a difference to take them before exercise or bedtime?
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@stealle I also have had great success with the Berkley NO booster supplements plus my celery habit. My saliva test strips (from Humann) are always good. My BP is lower in the AM now that I have resolved my NO issue. I avg 101 / 63; I used to be around 120/80.
I take 20 drops of MB (10mg) in the morning when I do not exercise in the morning. I believe the max safe dose is 2mg/kg (176mg for me). It has a 5-6 hour effect. I donât take MB when I exercise because MB constricts blood vessels (helps with shock, among other features).
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I take 1mg (1 mL of 1% MB solution) of MB every morning.
As far as I can tell methylene blue inhibits NO in a dose-dependent manner as one would expect.
Methylene blue is known to increase blood pressure by reducing NO in our bodies.
The doses required to significantly affect NO is higher than the 1mg (1 mL of 1% MB solution) that is recommended and the dose I have been taking for quite some time.
Since the dose I am taking does not have any observable effects on my blood pressure I am assuming it is safe.
I think supplementing with citrulline or other NO enhancers would probably be a good idea.
INHIBITION OF NITRIC OXIDE SYNTHESIS BY
METHYLENE BLUE
https://sci-hub.se/10.1016/0006-2952(93)90072-5
Iâve only been taking the Berkeley foundation x2 capsules with dinner for almost a week It only takes an hour after dosing for the test strips to read âOptimal.â The scale for the strips is âdepleted - low - optimal - high.â Iâve found that I am optimal from 1 hr to at least 16 hours. I have not been able to pinpoint âlowâ yet but Iâm back to depleted at 24 hours.
Any reason why Berkeley says to take 2 at the same time? Iâm wondering if splitting the dose might keep me optimal around the clock. Maybe itâs good for the level to swing as opposed to steady state? Joe do you take 2 at the same time in the evening? So you take MB mostly on rest days? In the am or pm near your NO dose?
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Need some clarification. I think you meant to say you take 10mg. Since 1ml of 1% solution = 10mg.
My bad, you are correct, 10 mg it is.
I take 2 capsules in the morning, which seems to keep my test strips in the âhighâ range until afternoon. I eat celery for dinner which gets me back to âhighâ when I test at wakeup. I think Berkley says 2 to get the dosage needed to get a âhighâ reading, but if you can get a good result from 1 capsule that is better. I havenât tried it to be honest.
I take MB on days when I donât exercise in the AM. The MB is gone by evening, so I donât worry about evening workouts. I have been taking my NO dose within 30-60 minutes of my MB dose when I take MB, but I think Iâll stop doing that since it doesnât make any sense. Thanks.
I tried supplements for NO and checked they worked with the strips but they significantly affected my HRV and heart rate at night so I stopped taking them. Maybe I should try again.
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Maybe take the supplement in the morning. The NO effect does not last all day. I take the supplement on the AM, and then I eat celery at night.
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A video posted today by Dr. Nathan Bryan
An interesting take on aging:
Unified Theory of Aging: 20:00 mark
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However, if we are short of Nitric Oxide then âwhy?â Rather than finding interventions to fix this, would it not be better to find an intervention to stop us being short of it.
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Itâs an age-related effect so you have to address aging.
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I like the idea that the age-related decline in Taurine, Glutathione and Nitric oxide should be reversed back to an almost youthful level. But I donât want to overdo it.
I think we agree on this point. I think i am doing this.
Tell me what that intervention is and try to use it.
An Overview of NO Signaling Pathways in Aging
Molecules | Free Full-Text | An Overview of NO Signaling Pathways in Aging.
âAccording to recent studies, aging is considered to be related to the greater protein acetylation levels and the defeat of sirtuin-1 deacetylation activity, which could subsequently cause the reduced eNOS activityâ
â Superoxide (O2â) increases within the vascular wall with aging, which decreases the bioavailability of NO, leading to endothelial dysfunction in agingâ
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