Vaccines for longevity

Yes of course. And this is not blaming patients for being scared and desperate. However, we should blame people who discourage people from getting vaccinated against preventable diseases, and who encourage people to ignore conventional medical treatments. Medical treatments for cancer definitely are not perfect, not even close. But forgoing treatment in exchange for a vegan diet and coffee enemas is insanity, and the people out there promoting that are exploiting people at their most vulnerable time. That is a major concern.

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What is going to happen is that the rich will vaccinate and the poor and middle class will be left to their own devices. The smart will propogate and evolution improves the gene pool.

Unfortunately, I watched the intro to Idiotocracy and that seems to be more likely as to what happens.

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Not all though, Elon is spreading his seed far and wide and he’s brilliant. Complex systems don’t have simple solutions. Crazy stuff happens.

No, I said he was spreading his seed far and wide and is also rich and brilliant. Opposite of idiocracy. I don’t know his position on vaccines.

My position on vaccines is that if the company making the vaccine is not liable for damage then safety and efficacy is unknown. I generally trust people (“the science”) but really we have no disease I’m that scared of at this time. If RFK manages to do tests that vouch for the safety and efficacy over time my mind could change. If someone else is in charge and they are pro vaccine and status quo then I don’t expect to learn the truth from them. The adversarial system has some advantages.

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Exactly… got my mpox shots - takes 2 shots a month apart, 2 years ago… as I travel a lot… and the virus is contagious by any contact… not just by sex (but just in case - :wink:).

And, the blisters from the disease they say and from pics is pretty nasty.

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https://x.com/agingroy/status/2011848328804278423?s=20


Source: https://x.com/agingroy/status/2011848331341820022?s=20

Related Reading:

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I just had the shingles and flu vaccines, so I guess the Tdap is next. Any other that might be better?

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That’s fair, but I think the reason the exemption exists is because vaccines have so much power to do good in the population, and we want to incentivise their development. It’s also because vaccines are recommended (or sometimes mandated) by the government and given to healthy people. So it would be quite unreasonable if the government are saying “everybody should take this, but the vaccine company takes the blame if it goes wrong”.

And it’s also not really true that they’re “not liable for the damage”. There is still the VICP, and most countries run something similar. My country (the UK) has a separate compensation program for vaccine-related injuries, again because liability risk would potentially threaten vaccine supply, price etc.

The unfortunate reality is that by failing to immunise people for HepB, there will be more cases, there will be more virus spread, and there will be more liver damage, liver cancer, and misery as a result. I literally can’t wrap my head around the decision-making or rationale of that one. Anybody can look at a number of asian countries which introduced HepB vaccines at birth and it’s been a huge success story. Nothing bad happened. No adverse events or long-term consequences. But chronic infections and liver cancer rates plummeted. (And those countries all have significantly longer life expectancies than the US).

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Last year I got shots for shingles, flu, Tdap, RSV, Covid, and pneumonia. I’ll probably look into getting a meningitis vaccine, also. Given my hospital visits last year I thought I would play it safe and load up on vaccines. (That’s probably a bad idea, as loading too many vaccines in a few months window might come with risks or might dilute the potency of the vaccines; but nobody tried to talk me out of it!)

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I want to get shingles vax but am afraid of side effects - I’m usually not lucky with sides. Got flu vax a month ago - it’s a disappointment that it’s not a good match for subclade K.

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As far as I know, there’s no evidence that this happens, by the way.

Your body deals with massive amounts of antigens every day. The tiny amounts given in a vaccine won’t overwhelm your system.

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I got a whole bunch before going on rapamycin, shingles, pneumonia, hep-a, hep-b, tdap, flu, covid and of course re-up yearly the flu and covid. Still left on my bingo card is rsv and maybe mpox when I get around to it. However, it’s important to keep in mind that the NDD “protection” such as there is, lasts only a limited time. For example, tdap against PD lasts about 3-5 years, and you need to re-up otherwise the protection fades. It’s probably the same for other vax, like shingles - which in any case you need to repeat every 10 years. Some are supposed to last a lifetime, but I think are still worth repeats, like pneumonia. There’s always some banter at my local pharmacy where I get my shots - usually it’s a bear trying to get people to take any vax, and there I am anxiously inquiring when is my next chance to get a shot whether I officially “need” it or not - and they’re always shocked when I tell them I am completely unconcerned with whether insurance covers it, and I’ll gladly pay the $400 or whatnot out of pocket… just keep those shots coming. I’ve lost count of how many covid boosters I’ve gotten since the vax became available - I’m sure the anti-vaxxers think I’ll be dead any day now, :rofl:

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“Turbo cancer” please!

Speaking of cancer, I was surprised where, at my kids school, there is some parental debate about HPV vaccines. I had to really hold my tongue from calling them idiots. You’ve got a vaccine which dramatically reduces risk of cervical cancer, anal cancer, throat cancer, tonsil cancer, tongue cancer, vaginal cancer, penile cancer, and reduces genital warts. But because it’s recommended, and free, and the schools come to ask if you want it, people are weirdly suspicious of it.

Somehow I also get the feeling that if they charged $10,000 for it and had an exclusive, limited supply, parents would be racing to try and get it for their kids.

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I don’t know what this means, but thought maybe somebody here would. I find positive thinking helps everything in life, but it’s important to know what’s going on. Most likely won’t hurt to think positively.

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Shingles vaccine linked to slower biological aging in older adults

Shingles vaccination not only protects against the disease but may also contribute to slower biological aging in older adults, according to a new USC Leonard Davis School of Gerontology study.

Using data from the nationally representative U.S. Health and Retirement Study, researchers examined how shingles vaccination affected several aspects of biological aging in more than 3,800 study participants who were age 70 and older in 2016. Even when controlling for other sociodemographic and health variables, those who received the shingles vaccine showed slower overall biological aging on average in comparison to unvaccinated individuals.

The study, “Association between shingles vaccination and slower biological aging: Evidence from a U.S. population-based cohort study,” is published in the Journals of Gerontology, Series A: Biological Sciences and Medical Sciences.

In the new study, Kim and co-author Eileen Crimmins, USC University Professor and AARP Professor of Gerontology, measured seven aspects of biological aging:

  • inflammation
  • innate immunity (the body’s general defenses against infection)
  • adaptive immunity (responses to specific pathogens after exposure or vaccination)
  • cardiovascular hemodynamics (blood flow)
  • neurodegeneration
  • epigenetic aging (changes in how genes are turned “off” or “on”)
  • transcriptomic aging (changes in how genes are transcribed into RNA used to create proteins)

The team also used the measures collectively to record a composite biological aging score.

Surprising results beyond shingles prevention

On average, vaccinated individuals had significantly lower inflammation measurements, slower epigenetic and transcriptomic aging, and lower composite biological aging scores. The results provide more insight into the possible mechanisms underlying how immune system health interacts with the aging process.

Chronic, low-level inflammation is a well-known contributor to many age-related conditions, including heart disease, frailty, and cognitive decline. This phenomenon is known as “inflammaging,” Kim said.

“By helping to reduce this background inflammation—possibly by preventing reactivation of the virus that causes shingles, the vaccine may play a role in supporting healthier aging,” she said.

“While the exact biological mechanisms remain to be understood, the potential for vaccination to reduce inflammation makes it a promising addition to broader strategies aimed at promoting resilience and slowing age-related decline.”

These potential benefits could also be persistent. When analyzing how the time since vaccination affected results, Kim and Crimmins found that participants who received their vaccine four or more years prior to providing their blood sample still exhibited slower epigenetic, transcriptomic and overall biological aging on average versus unvaccinated participants.

“These findings indicate that shingles vaccination influences key domains linked to the aging process,” Crimmins said.

“While further research is needed to replicate and extend these findings, especially using longitudinal and experimental designs, our study adds to a growing body of work suggesting that vaccines may play a role in healthy aging strategies beyond solely preventing acute illness.”

Paper

Association between shingles vaccination and slower biological aging: Evidence from a U.S. population-based cohort study, Journals of Gerontology, Series A: Biological Sciences and Medical Sciences

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I can’t do it, I do not trust the pharma companies and the propaganda…

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Understood. Each of us has to use our best judgment. I look at the balance of evidence, and opt to get every sensible vaccine I can get my hands on. Others - such as yourself - make a different call. Thank heavens each of us has the opportunity to make that choice for ourselves. Who is right? Who knows - that’s for Dr. Darwin to decide.

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I have also taken whatever vaccines I could get my hands on. In the last two years I have taken Shingrix, TDAP, RSV, PCV20, Flu. Scheduled to take TWINRIX and Gardasil 9 (I am in my upper sixties) in the next few months. I have had a couple of TB vaccine shots, last one when I was 16. Don’t think I am going to get another one. I have been vaccinated against Smallpox. I suspect I have had typhoid vaccine but my memory is very hazy. If I have missed anything let me know and I will investigate (no anthrax please!)!

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For those interested in this, the Children’s Health Defence is having some kind of legal action against The American Academy of Pediatrics. On RICO grounds, alleging they ran a racketeering scheme by repeatedly making false claims of the absolute safety of childhood vaccines and the ever-expanding vaccine schedule all while receiving funding from vaccine manufacturers for recommending and administering them. This is from the blog of Dr Michael Eades:

I’m not much of a lawyer or doctor for that matter. But if you think the doctors are finding the cures, you may also believe the lawyers are finding the truth.

Doctors don’t find cures, researchers do. Vaccines do have the potential to cure many conditions like cancer and persistent viral infection.

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