Started taking Rapamycin

Hi
After having all the blood tests that Dr Green recommended, and receiving the results which were all good, I started taking Biocon Rapamycin. I started with 1mg but second day felt a bit uncomfortable stomach wise. Thought it may be just something I had eaten, but kept to 1mg the week after with no problems.

I am now up to 3mg and feel fine. One thing I have noticed is my appetite is reduced when I normally have a late breakfast around 11am. Strangely I have lost the desire to eat a high protein breakfast in the morning. Normally I am the type of person who finds it difficult to stop eating once I start until Iam really full.

At this moment I stopped eating an hour and a half ago and I still feel quite full.

I suppose because RAP downregulates Mtor a protein kinase it may at certain times restrict the desire to eat lots of protein at once

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I have also noticed feeling more satiated the first 2 days after taking rapamycin. I’m a lot less snacky. My wife has the exact opposite experience though. She craves carbs more than usual.
It’s funny, because normally we’re opposite.

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I actually noticed that I crave carbs as well, but never though of it from rapa perspective , rather more from winter is here and is cold outside and I need more calories.

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Yes I also noticed carbs seem to be the thing I go for. I generally start with an avocado and a few nuts to limit insulin spikes, then I eat carbs. Usually before starting on Rapa, I ate half a can of Salmon and 120 grams of beans. I eat these later in the day now.

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