Scientists Discover That Taurine Promotes Anti-Aging

It’s a fascinating article.

If I recall correctly, I believe somewhere it says that NAC increases taurine, and that might explain some of NAC’s benefits. I wonder what the effect of taking both? Would it be merely cumulative, or amplified somehow?

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Consumerlab is great, and there are others:

Others:

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Here is what I’ve seen about the taste of the taurine powder:

It is reputed to be slightly bitter and sour. I down about 1 liter of distilled water fortified with ~0.25 g each of mixed minerals, brewers yeast, AKG, & HMB, in nine big gulps first thing in the morning, and intermittent gulps through the day. It is almost flavorless, but a drop of vanilla makes it down-right appealing.

Here is some more on Taurine oral bioavailability, half life and dosage tolerance:

image

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or here
https://archive.ph/kxpQX

This articles as short viewpoints from some scientists in the field as well.

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Has anyone done testing of their taurine levels? If so what provider?

Seems like levels are very age dependent. So perhaps optimal dosing will be lower for younger people and higher for older people?

Is this a case where strategy might be more based on targeting a certain blood level (such any many do with their Vitamin D levels or eg Lustgarden and Blueprint we’re doing for NAD) rather than targeting the input level?

Saw that taurine is part of LEFs amino acid panel below (and it was on sale when I looked).

Might be good to test levels before and after starting/changing taurine dosages.

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Yes; there is evidence of synergy between taurine and NAC. I was taking both.

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Related articles concerning taurine.

The Beneficial Effects of Taurine to Counteract Sarcopenia

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040170/

Taurine Attenuates Catabolic Processes Related to the Onset of Sarcopenia

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700215/

Taurine Administration Counteracts Aging-Associated Impingement of Skeletal Muscle Regeneration by Reducing Inflammation and Oxidative Stress

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137670/

Taurine as a possible antiaging therapy: A controlled clinical trial on taurine antioxidant activity in women ages 55 to 70

https://www.sciencedirect.com/science/article/abs/pii/S0899900722001198?via%3Dihub

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Taurine 1,6 gr/day boosts H2S. Hydrogene sulfide.

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As I posted at the start of this thread;

An idea to take taurine with rapamycin,?

As there was/is a company that was selling rapamycin capsules cut with only taurine .

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Examine has a nice review of taurine use and usage

" Serious adverse effects have not been reported with taurine supplementation.[24] The highest dose used in a human trial was 10 grams per day for 6 months, and the longest human trial was 12 months and used a dose of 0.5–1.5 grams per day. Based on the available evidence, it’s suggested that 3 grams per day can be consumed indefinitely without risk of side effects."

I started taurine about a year ago intermittently for sleep (based on one of your postings). Then saw it was good for endurance training as it resides in slow twitch muscle type, and I was training for a triathlon. Then I saw that TongMD uses it and he is very particular about this supplement usage.

I take 2grams with coffee, no food, in the morning. Within 2 hours of a workout. Apparently taking without food means it doesn’t compete with other amino acids and is therefore better absorbed. (completely unsure if my understanding is correct). I take 1gram before bed. It does have an affect on mood apparently.

Like you I have little clue about its efficacy on myself, but yippee that the research is so positive and broad in its virtues!

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More interesting research on Taurine:

Taurine Supplementation Lowers Blood Pressure and Improves Vascular Function in Prehypertension: Randomized, Double-Blind, Placebo-Controlled Study

The Effects of Oral Taurine on Resting Blood Pressure in Humans: a Meta-Analysis

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Pushback on the Taurine recent research and press narrative by Karl Pfleger, ex Google AI guy, and a major angel investor in the longevity biotech space in the San Francisco Bay Area: (note, Karl is also pushing back on the Hyperbaric Oxygen research, and is also not a big fan of metformin or rapamycin because he feels that the mice in the research are fed ad-libitum which is equivalent to over-feeding, so he feels that most of the effect of the metformin and rapamycin is reducing the negative effect of over-feeding. Karl at a personal level is pretty good at low calorie living… i.e. CRON (Calorie restriction with optimal nutrition).

But - back to Karl’s Taurine commentary:

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Taurine is made by the body from cysteine and hypotaurine.

https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=19&contentid=Taurine#:~:text=Adults%20can%20make%20their%20own,a%20neurotransmitter%20in%20the%20brain.

Cysteine can be found in an array of foods including broccoli, Brussels sprouts, egg yolks, garlic, oats, onions, poultry, red bell peppers, wheat germ and yeast.

https://restorativemedicine.org/library/monographs/cysteine/#:~:text=Cysteine%20can%20be%20found%20in,peppers%2C%20wheat%20germ%20and%20yeast.

https://www.webmd.com/diet/foods-high-in-sulfur#:~:text=Nuts%2C%20seeds%2C%20grains%20and%20legumes,sources%20of%20this%20amino%20acid.&text=turkey%20and%20walnuts-,Chickpeas%2C%20couscous%2C%20eggs%2C%20lentils%2C%20oats%2C%20turkey%20and,getting%20cysteine%20through%20your%20diet.

Webmd says sulfur containing foods help the body to produce cysteine.

So vegans can auto-produce taurine with the the plant-based food items above.

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Taurine strikes me as a good “risk reward” supplement, kind of like glycine. I’ve taken it in the past as I thought it helped me a bit with exercise recovery.

In my experience, when taken at night in higher doses (3g+), it will cause a middle of the night awakening. This effect doesn’t occur at 1g, and once you build tolerance after a few weeks it doesn’t occur either.

Just something to be wary of – if you take 3g+ and wake up too early, back off for a bit then try restarting.

I don’t take it during the day often (or if I do it’s with plenty of caffeine) because I find it slightly sedating.

YMMV.

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Tried some Taurine powder. As far as I can tell, little to no taste, so can probably mix with anything.

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Effects and Mechanisms of Taurine as a Therapeutic Agent

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New article about taurine.

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I remember reading that taurine tastes good mixed with glycine in water. So I might try that on an empty stomach.

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As best, I can tell everything tastes good with glycine!

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Glycine tastes like the sweetest powdered sugar you have tasted. And it’s good for you. And it’s pretty cheap.

Why do we use regular sugar???

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