Rapamycin Rejuvenates Oral Health in Aging Mice

The mice were given encapsulated rapamycin orally ingested:

rapamycin rejuvenates the aged oral cavity of elderly mice, including regeneration of periodontal bone, attenuation of gingival and periodontal bone inflammation, and revertive shift of the oral microbiome toward a more youthful composition.

I again wonder how effective a rapamycin toothpaste will be for me and others? Will it complement oral ingested rapa pills?
I don’t plan to get an oral microbiome analysis, as Mike Lustgarten recently did, but I’m betting that rapamycin is at least as effective his mouthwash.

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