Rapamycin etc., Purchase Price Comparison Spreadsheet, and Issues Discussion

Here is a recent cost estimate of some medicines of interest from Jagdish of RL Pharma. I expect the prices will go down a little when ordering in quantity. I’m tempted by the 3 mg siroboon since it means taking fewer pills and it’s less expensive, but based on comments in this thread, I’ll probably go with rapacan, which is produced by Biocon, whose quality control I know to be solid.

Any thoughts?

1- Glucobay 25 Tablet , Acarbose 25mg = 1.2 USD for 10 Tablets.
2- Glucobay 50 Tablet , Acarbose 50mg = 2.4 USD for 10 Tablets.

3- Brillo EZ 180mg/10mg Tablet , Bempedoic acid (180mg) + Ezetimibe (10mg) = 5 USD For 10 Tablets.

4- Invokana 100mg Tablet , Canagliflozin (100mg) , Johnson & Johnson Ltd = 7.5 USD for 10 tablets.

5- Jardiance 10mg Tablet; Empagliflozin (10mg) = 7.2 USD for 10 tablets
6- Jardiance 25mg Tablet;Empagliflozin (25mg) = 8.8 USD for 10 tablets.

7-Rapacan 1mg Tablet ; Sirolimus (1mg) ; Eris = 6.5 USD for 10 Tablets.
8- Siroboon 1mg Tablet ; Sirolimus (1mg) = 5 USD for 10 Tablets.
9-Siroboon 2mg Tablet ; Sirolimus (2mg) = 8 USD for 10 Tablets.
10- Siroboon 3mg Tablet ; Sirolimus (3mg) = 11 USD for 10 Tablets

Hi, just wanted to add some information about the rapamycin supplier G.P. Pharma in India. I just ordered the second batch of 100, 1mg rapacan tablets, manufactured by Biocon. Total cost was $125USD. I ordered this on 6/15/2024 and it was delivered by USPS to my residence on 7/5/2024.
There was a couple, few days of them not replying to my request for tracking#, after ordering and knowing they received my payment. But they updated me eventually.
They use an India Post tracking number, that is transferred to a USPS tracking number after ariing and going through US customs.
As with the first batch, this will last me about a year, as i take 2, 1mg tablets roughly once a week with a small 6 or 8 ounce cup of grapefruit juice.
Pics of front and back labels of package that arrived are included. Package was carboard box wrapped in heavy, blue paper with lables taped to the box, as was the first package over a year ago.


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Your prices for Siroboon are too expensive. That’s what I paid for Zydus brand. Also, the other brand you are comparing it to is made by Eris Pharmaceuticals (for Rapacan?). We do not know the quality of that brand.

Bempedoic Acid is just what I paid. Ignore the USD typo. It’s all INR. I like stocking up on Rapa, but even I wouldn’t buy $93,000 USD worth. :wink:

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You prefer to pay in INR because you’re in HK and exchange is better? Is that right?

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Yes, the exchange rate worked out better for me this way.

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Great to know that Eris is the marketing company only.

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Since you can get Rapa at CVS pharmacy for less than $1 per 1mg tab, why would anybody be messing around with India or china? I got my first Batch of Rapa from India. The quality seemed good. Then I found that a dood rx coupon at CVS pharmacy had Rapa for less money and zero risk of getting a poor quality. Now I get it from CVS. It’s cheaper a lot cheaper. About $5 per 6mg dose.

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Maybe because we don’t want to screw around with personal physicians, who mostly won’t prescribe it anyways, or website doctors who are likely to prescribe small amounts that would have to be renewed every few months at a significant cost.
And, if you are not getting Pfizer, it is probably inferior to Zydus or Biocan

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Another reason may be because people want to order a number of medications (that may be harder to get prescribed in their country, like bempedoic acid, ezetimibe, SGLT2 inhibitors, acarbose, etc.) so its just easier to order and get them all together.

But for most people who are just taking rapamycin, I would agree with @bobo , just talk to a doctor in the US and get a prescription and buy from a low-cost trusted source in the US.

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The CVS rapamycin is Dr Reddy’s, I believe. The same that supplies the generic for Healthspan.

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that is about same as getting it from India, but CVS would not sell it without a doctor’s script, and the cheapest to pay for a doctor online I think it is $45 (if you can find one willing to put you on RAPA), nevertheless that price from CVS is very reasonable.

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Yes, the price now is almost the same for India sourced and USA sourced, and there are advantages to working with a doctor in the USA, and to knowing your medicine is not stored in some guys hot apartment in Delhi😉 before it’s shipped to you.

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Well I got a years supply recently from CVS. Before that I got a supply from India.The first order was seized by customs. After 30 days the company that I ordered it from sent me a replacement order. I received that order. I have a pretty low opinion of the FDA and pretty much any other government agency. But I figure if I get a supply from CVS for a similar or lower price from India, I’d rather go with CVS. No potential customs hassle and no worries about the quality of the product, hopefully, LOL! It’s a personal choice. And I totally respect the choices that others choose.

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You are 100% right, stateside sourcing is absolutely preferable. That said, it’s not an absolute - in another thread, someone posted how Dr. Reddy’s (Indian pharma) which distributes in the U.S., had to issue a second recall for impurities, and when even U.S. pharma uses subcontractors or sources ingredients from dodgy places like China, you’re taking a risk (cancer causing BP and PPI meds recalled).

But again, on balance you are right about quality trust. The reason some of us opt for Indian pharmacies is not just the hassle of getting a scrip, but frequently we’re buying other meds at the same time, which are far more affordable and again without prescription hassles. So if you’re already buying 3 meds, may as well throw in the rapa at the same cost, out of pure convenience. That said, random seizures by customs are a huge drag, not to mention the stress of waiting to see if you pass the lottery or come up bad… I’m going through it now, watching one of my packages stuck (in customs?) for days now with no updates. I’d gladly pay a couple of bucks more not to have to go through this song and dance; alas, that’s not always an option… unless you have millions and can buy a doc and meds with your spare change. Right now it’s the lottery for me.

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For the record, I paid $172.00 for a years supply of rapa. That’s about $3.30 for a 6mm dose. To that add the cost of the prescription.

A doctor’s prescription may run you about $45. But shipping fees from India will run about $35. I’ll pay the extra $10 to source locally.

If I lived in the USA that is… :wink:

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Latest prices from Maulik

800 tabs of Galantamine (4 mg) - 240$ - Sun pharma
800 tabs of Empagliflozin (25 mg) -640$ - Boeringer Ingelheim
800 tabs of Bempedoic Acid + Ezetemibe - 280$ - Sun pharma
400 tabs of Telmisartan (80 mg) - 60$ - Healing pharma
400 tabs of Metformin (500 mg) - 20$ - Healing pharma
Shipping in preferred in 2 packages - 60$
Total - 1300$

Has anyone heard of Healing Pharma? That’s a new brand for me. The others are top notch.

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Hi Chris,

I’m consuming the Healing Pharma Telmisartan product for almost 9 months now and I can confirm that it definitely lowered my BP by the expected amount, so I have no reason to think that it is not the real thing of decent enough quality (as in I’ve seen no side effects from it).

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Anyone order injectable testosterone cypionate from India? I bought some while visiting India and am wondering if there are issues sourcing it from India online, particularly passing through customs given that it’s a Schedule III controlled substance.

Note that although I’m following a medically supervised TRT program and have a prescription, I now live in the Philippines where it is expensive to buy and customs are unpredictable with seizures. The prescription is difficult to fill in the US since the doc that wrote is overseas (although he’s licenced in California), so it’s just easier to buy it from India if that’s possible. I plan to pick up other drugs ordered from India when I visit the US soon.

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Hi, I tried Healing Pharma’s bupropion XL and worked as expected

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