Rapamycin Cycling (Time Off) - Who Is Right?

What was your weekly dose before? Also what do you mean when you say your kidney function recovered? Thanks!

I used to take 6-8 mg a week (I even went up to 20 mg). My creatinine had suddenly risen by 40%, and is now almost back to my initial value.

Creatinine is affected by lots of things as well as kidney function.

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I also had oliguria and other signs of AKI.That said, my kidneys were already weakened

40% is a lot. That said rapamycin appears to raise blood serum creatinine levels by 20%.

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As John Hemming says “Creatinine is affected by lots of things”.
I have taken many blood tests over the past 2+ years I have been taking rapamycin.
There is no discernable correlation between my rapamycin intake and my creatine readings.

I’ve been taking Rapamycin for over a year, and my creatinine levels have dropped to just below the lowest point in the normal range. If your creatinine went up, there’s probably confounding factors involved.

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My creatinine was .92, which is a very good number for me. However, it just jumped up a lot, without any changes in rapamycin dose. I blame viral infection and antibiotic that I took.

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