“Cognitive decline”
I honestly could care less about that, I do some precautions.
Most people do not care about that, as evident by the fact of the copious amount of people who smoke marijuana, drink alcohol, never exercise, or have other habits which probably decrease cognitive function over time. Most important thing is to have a good intelligence baseline… I think most of us will be in the normal intelligence range even with expected cognitive decline from statins (which is low, because of uncertainty).
Evidence for Alzheimer’s disease and dementia is embarrassingly weak. They will probably help prevent vascular dementia, and other problems with the brain from reduced blood flow due to atherosclerosis. The net effect, I think statins help with cognitive function (+ by preventing atherosclerosis).
Some people do hesitate to take statins because they’ve heard about others who have had symptoms related to statin use, such as brain fog, muscle pain, and liver problems, she says.
Check out Citrus Bergamot, brings down cholesterol with 15-20% within short term use. It did for me, got this recommended from a few comments on Consumerlab.com. Decided to try it and law and behold it came down 20% for me as well. Not the cheapest supplement, but worth a try.
Yes, but high risk patients and diabetics. Steve Nissan from Cleveland Clinic, and one of the authors, stressed in an interview that if you’re high risk, especially if diabetic, then you should lower your lipids with meds.
No arguments there.
At 1000 mg of CB my LDL dropped 20% along with my triglycerides. HDL up 25%.
I haven’t yet repeated my critical ApoB and A-1. Have also introduced Amla and taurine to the mix. Will check soon.
Regardless, several studies are consistent in finding lipid lowering with CB. Very impressive. Doses up to 1500 mg’s. No side effects noted in any of them except for some mild heartburn.
Most of us want an LDL that is lower than 128, so it isn’t as effective as a PCSK9 inhibitor or high dose statins (or combo with ezetimibe). If someone can show an LDL or apoB of 60 combining different supplements, that would be interesting for many of us.
The jury is still out for me. I have used citrus bergamot on and off over the years and for other reasons than lowering LDL. I am currently using it to see if I can get my LDL lower. Unfortunately, it takes time to make valid tests as there are some other variables involved with me. If there was a significant lowering of LDL while using it I failed to notice. Maybe it is more dose dependent for some people.