https://www.medscape.com/viewarticle/993666
“Striking” effect of specific lipid-lowering therapy with bempedoic acid in primary prevention.
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Check out Citrus Bergamot, brings down cholesterol with 15-20% within short term use. It did for me, got this recommended from a few comments on Consumerlab.com. Decided to try it and law and behold it came down 20% for me as well. Not the cheapest supplement, but worth a try.
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What dosage are you using?
Still, no one has said what their apoB or LDL is who have taken citrus bergamot or other supplements.
Do you mind saying what yours is?
Yes, but high risk patients and diabetics. Steve Nissan from Cleveland Clinic, and one of the authors, stressed in an interview that if you’re high risk, especially if diabetic, then you should lower your lipids with meds.
No arguments there.
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At 1000 mg of CB my LDL dropped 20% along with my triglycerides. HDL up 25%.
I haven’t yet repeated my critical ApoB and A-1. Have also introduced Amla and taurine to the mix. Will check soon.
Regardless, several studies are consistent in finding lipid lowering with CB. Very impressive. Doses up to 1500 mg’s. No side effects noted in any of them except for some mild heartburn.
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And what has your LDL dropped to, if you mind, what is the absolute number?
Thank you. Started it some time ago, along with Psyllium Husk. Also added Pantethine 600 mg. Had to stop rosuvastatin bc of muscle pain.
LDL was 80 ish for most of my life . Same with triglycerides.
On rapamycin went up to 160. Down to 128 on CB.
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Most of us want an LDL that is lower than 128, so it isn’t as effective as a PCSK9 inhibitor or high dose statins (or combo with ezetimibe). If someone can show an LDL or apoB of 60 combining different supplements, that would be interesting for many of us.
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I am using Jarrows Formula 500mg twice a day, with dinner and before I go to bed.
I am not sure I understand the question, do you want to know my lipid numbers before and after Bergamot?
You can see my history of ApoB scores below. You see those scores in the 90’s? That’s when I was on citrus bergamot. Didn’t do anything for me.
Zetia got me down to the 60’s, then adding Bempedoic Acid my ApoB went down to 46
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The jury is still out for me. I have used citrus bergamot on and off over the years and for other reasons than lowering LDL. I am currently using it to see if I can get my LDL lower. Unfortunately, it takes time to make valid tests as there are some other variables involved with me. If there was a significant lowering of LDL while using it I failed to notice. Maybe it is more dose dependent for some people.
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Chimps don’t get heart attacks despite high blood pressure and high lipids. Could be due to one gene lost in humans.
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It appears once again that combating inflammation, especially long-term low-grade inflammation is probably more important than pursuing anti-oxidants.
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All of the evidence points in that direction for sure, though there’s a fair amount of overlap, especially in foods.
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Vince G. knows alot about aging, and virtually every intervention, and he very much stresses controlling inflammation
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When they replace that one, can they put the one in that makes vitamin C out of glucose?
I don’t know why we let that one go either.
Thanks, I’ll give it a try.