Plasma Exchange vs. Plasma Donation: Longevity and Healthspan Benefits

Plasma Exchange vs. Plasma Donation_ Longevity and Healthspan Benefits.pdf (118.0 KB)

I paid for ChatGPT Plus this month to test out the latest Deep Research features and I’m really impressed by its capabilities.

This was the prompt I used: "The longevity field is touting plasma to albumin exchange as a longevity treatment. There are claims it can reduce microplastics and provide other benefits emulating heterochronic parabiosis studies.

How does this compare to simply donating plasma, something that is free in my country?

I am looking for scientific evidence comparing their respective health and longevity benefits in humans, as well as any compelling model organism data that strongly suggests health benefits in humans.

I am interested in biological mechanisms and practical outcomes for people in general.

I am also interested in which health conditions might make either of these treatments not advisable due to risks. I am interested in which health conditions might particularly benefit from this.

I want a review of recent clinical studies and expert opinions.

Once all of that has been detailed, I would like a concise summary of the benefits and risks of both, and a decision on which is better overall, and then a weighing of the $ cost to benefit ratio."

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