Telmisartan is the only BP med I am taking. I was taking 40 mg, but 20 mg in the morning seems better. I do take citrulline at night which also helps.
My BP seems to be staying pretty consistent all day long as measured by my Contec device at home.
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Am planning up my Temisartan to 80mg per @DrFraser recommendation here.
Anyone else who has tried 80mg and what are the result of it?
I have been taking 80mg telmisartan for the better part of a year now. My systolic runs about 10-15 mmHg lower than when it was untreated. I haven’t had any issues.
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I started telmisartan 2 years ago in order to drive BP down to below 130.
Although 40mg was sufficient when measured at home, I was still getting high readings (over 130) in the doctors office.
I’ve now been at 80 mg for about a year, getting home BP readings typically at or below 110 SP. To prevent occasional lightheadedness due to DP in the mid 50’s, I found that splitting the dosage to 40mg twice a day solved that issue.
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I have had the same experience. I’m rushing to an appointment, stressed, SBP is 135, which at rest is 115. This is stress. I think it’s that simple, and I don’t think it’s something to get stressed about. Lol.
My resting HR is also high and has always been high, despite the fact that I have good body composition and aerobic fitness and have never smoked. My resting HR is around 70, while my athletic friends, whom I have trouble keeping pace with on a hike, will be in the 60s. Some of us are just clocked differently. I’m not saying we shouldn’t try to do something about it, but I think our baseline is different.
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I have HR and BP measures back to 2016, but more detailed records more recently. The BP/HR measures are, however, comparable.
I used to have a HR in the 70s 80s and now it is in the 50s. I don’t think that is genetic.
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For the record, I’m not saying that behavioural changes or pharmacology aren’t influential—perhaps more influential than genetics. I’m saying that genetic influence on pulse rate should be considered when developing a strategy for pulse-rate reduction. Because you have been successful in reducing your heart rate by doing whatever you did, it does not mean I can expect the same results following the same plan. We see this in most biomarkers we try to influence, glucose, fat, apob, etc.
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John - what do you think the key factors are that helped you accomplish this HR reduction?
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Its hard to identify one or two changes.
Researchers at the University of California, San Diego School of Medicine have identified a potential new treatment for individuals with uncontrolled or treatment-resistant hypertension, a condition commonly referred to as high blood pressure. The investigational drug, lorundrostat, showed encouraging results in a recent clinical trial.
Published in the New England Journal of Medicine, the study found that participants who received lorundrostat experienced an average 15-point reduction in systolic blood pressure, the upper number in a blood pressure reading, compared to a 7-point reduction in those given a placebo.
https://scitechdaily.com/scientists-have-found-a-drug-that-slashes-blood-pressure-in-weeks/
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I’ve been taking telmisartan for about 5 months, bumping up to 80mg not long after I started taking it. No side effects so far as I can tell. If anything there’s been a very subtle mood boost.
Want to experiment with higher doses, but would monitor serum K+ more closely if I end up doing so. It’s only one anecdote but Reddit user OutrageousBit2164 says “I take 80mg daily but when I ramp up to 160mg there is clearly antidepressant effect, more vivid colors, anti anhedonic effect, music sounds better”
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