New Study: Ultra-Processed Foods Linked to Increased Risk of Cancer & Death

One of the issues here is that while increasingly this risk has become well-known over the past decade. The bigger issue is that for most people I know, there has been a seemingly inexorable trend towards increasing use of pre-packaged foods because of long work hours and busy lives… work, and family pressures are hard to balance, and pre-processed foods seemed to be a huge help. But now we realize “not so much”.

I’ve moved much more to simple, whole food but many people like the taste of more complex tastes of foods and that tends to require more time, or purchasing of pre-processed foods.

Researchers from Imperial College London’s School of Public Health have produced the most comprehensive assessment to date of the association between ultra-processed foods and the risk of developing cancers. Ultra-processed foods are food items that have been heavily processed during their production, such as fizzy drinks, mass-produced packaged breads, many ready meals, and most breakfast cereals.

Research Paper:

Reference: “Ultra-processed food consumption, cancer risk and cancer mortality: a large-scale prospective analysis within the UK Biobank” by Kiara Chang, Marc J. Gunter, Fernanda Rauber, Renata B. Levy, Inge Huybrechts, Nathalie Kliemann, Christopher Millett and Eszter P. Vamos, 31 January 2023, EClinicalMedicine .

Background

Global dietary patterns are increasingly dominated by relatively cheap, highly palatable, and ready-to-eat ultra-processed foods (UPFs). However, prospective evidence is limited on cancer development and mortality in relation to UPF consumption. This study examines associations between UPF consumption and risk of cancer and associated mortality for 34 site-specific cancers in a large cohort of British adults.

Interpretation

Our UK-based cohort study suggests that higher UPF consumption may be linked to an increased burden and mortality for overall and certain site-specific cancers especially ovarian cancer in women.

Related reading:

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This is not the first.There was one by Chinese researchers last year (I asked for PDF on reddit’s /r/Scholar). The press release accompanying that mentioned hummus, which surprised me.

I really want to know if this is inclusive of fake meat (esp beyond meat) and keto breads, which are also both ultra-processed, but not nutritionally as problematic as potato chips or bagels…

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It would be really nice to get a list of foods that are non-obvious (like bread for example, I was surprised by this) that are considered “ultra-processed”. Other than McDonalds and pretty much any PepsiCo or General Foods products - its not always completely clear what is ultra processed.

Hummus? Really?

https://www.washingtonpost.com/wellness/2022/09/27/ultraprocessed-foods/

https://yj.tips/body-health/5-examples-of-ultra-processed-foods-that-might-surprise-you

What is ultra-processed food? | Heart and Stroke Foundation.

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Spain and Italy consume way less than UK, which might explain lifespan difference (it’s not huge and they do smoke more and still eat other shitty food, but it’s still significant in light of them being poorer)

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Counterpoint? (I have a browser add-on installed that flags studies with pubpeer comments.)

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Hong Kong eats a lot less ultra-processed foods. Lots of fresh vegetables and fish. This could be why it has the highest life expectancy in the world. Same for #2 Japan.

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Full article says:

“The mean UPF consumption was 22.9% (SD 13.3%) in the total diet.”

Their definition of UPF is:

“(4) UPFs, e.g. soft drinks, mass-produced industrial-processed breads, sweet or savoury packaged snacks, breakfast ‘cereals’, reconstituted meat products and ready-to-eat/heat foods.”

A can of coke has 140 calories. If they have two, that is 280. A Danish has 106 calories. So it looks more like it is the soda and sweet stuff that are the culprits. You can throw in the instant ramen (188 calories), survival food of college kids.

Looks like clickbait to me.

It’s probably not because of the processing but the dietary fat composition in the diet. In 1980 non-HDL-c it was low while in Western countries very high. The older population had a lower apoB + non-HDL-c throughout their lives:


https://www.nature.com/articles/s41586-020-2338-1/figures/3

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Lol I ate a pack of Beyond Chips today, it was addicting, I was glad I just ordered one.

Most of the other ThinSlim Breads are fine (the breads are less addicting than the chips or more processed foods).

I also fall for Beyond Meat, but don’t eat it that often. Tbf I don’t think it’s as problematic as most other processed foods, but it should still always have an asterisk after it bc it’s a giant unknown

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More good reasons not to eat at McDonalds :wink:

Global Surge In Colorectal Cancer Linked To Junk Food

A lethal cancer which can go unnoticed for years is striking down younger people at an increased rate. While cancers have steadily fallen over recent decades, scientists have been mystified by an explosion of colorectal cancer cases, also known as colon or rectal cancer, in younger adults who have traditionally been at low risk of the disease. But scientists have now found a link between the notoriously hard-to-treat cancer and processed or “junk” food such as packaged snacks, hamburgers, fries, cereals, desserts, and sugary drinks.

Colorectal cancer is a disease characterized by the uncontrolled growth of cells in the colon or rectum. It often starts with the formation of abnormal growths known as polyps in these areas, which can eventually progress into cancer.

In August 2023, researchers at the Salk Institute and the University of California, San Diego, found that high-fat diets change the composition of the gut microbiome, encouraging the growth of bacteria that boosts the production of digestive molecules called bile acid in mice. These caused inflammation, which increased the chance of colorectal cancer.

Full article: https://archive.ph/KzMPa#selection-885.0-903.326

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The more I see “nutritional research” the more I want to go full on McDonald’s diet. Have. To. Resist.

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Sorry people, extra virign olive oil is processed. You can’t have it. Neither protein powder.
Someone tell Bryan.

Conclusions

Our study showed that high UPF intake increased the risk of CVD and was associated with several protein biomarkers. Future studies are warranted to validate these findings and assess the potential pathways between UPF intake and CVD.

image

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It seems like protein powder might have some issues - e.g. to what extent are there perhaps glycation issues…? (Was another thread on that and it was being looked into)

(For what it’s worth Peter Attia seems to have cut down on protein powder (reason I don’t know) and even Bryan Johnson has it as a very small part of his entire diet (just 29 grams or something - and he carefully selected it))

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