Yes everything looks great. For the transaminases I was sore from almost all my muscles so it might come from there.
The total blood work was 178.33€. I paid for everything.
Yes everything looks great. For the transaminases I was sore from almost all my muscles so it might come from there.
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Good price. I would pay in Germany over 300 for that for sure.
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Good update. Amazing condition!
If you have not already, consider doing a pro photo shoot in your current condition, or get a tripod to use your phone or other camera, with a photo backdrop(or green screen) to take your own photos and edit yourself.
Some ideas with the Iron issue:
Perhaps try another iron product that is not chelated, or add in some vitamin c (100mg+) with the Swanson iron product away from calcium or coffee.
You might be consuming too much calcium per day that is doing something with lowering iron.
Having a lot of coffee can lower iron also. Or it might be something else all together.
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Man your food looks so good. I always just make a giant bowl of stuff without caring what it looks like and eat the same thing most of the day lol.
Damn how long on tirzepatide until I’m this ripped? Did you titrate the dose up? I’ve moved from 2.5mg to 5mg, and I’m going to increase the dose by 2.5mg every 5th dose according to the official guidelines.
Usually it looks pretty bad, but sometimes I like to take a picture so I do some effort lol
I eat the same stuff every day usually, sometimes some beans, fish, but not that much. Too much fiber already. Can’t really handle more tht 75g a day without inconfort from bloating.
I started tirzepatide when I was 81kg fat -no muscles- at 5mg (big mistake) and increased the dosage when weight loss stopped. I when down to 58kg skinny but really low BF in I think 5/6months. I was up to 20mg a week.
I look really shredded but keep in mind tht these pictures are taken after my shift in the restaurant where I work next to a furnace and after eating, so the veins pops and I’m a bit dehydrated. In the morning it is less impressive.
Actually I’m still using it at 10mg a week and I might go up next week to 15mg because I’m still able to eat 4000kcal without difficulties. The main problem is constipation for me, but a constipation like it takes more time to go from stomach to the toilet, it is not hard to poo. Melanotan definitely helps with hunger too, and tan me pretty well.
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Thanks. No it is not planned, I just do it for me, and the fact that I used to be obese, and fat most of my life makes me a bit phobic of taking fat weight. I have a bit of loose skin on the lower abs and this gyno that I don’t really like on picture, so no photoshoot right now! With the pharmacological drugs I’m using I can almost stay that lean year around without difficulties.
Testosterone is of course supra physiological but not that high, and the combo salbutamol/mirabegron/yohimbine/coffee helps me burn the fat easily. Heart wise I was a bit worried but troponine is undetectable, RHR in the morning is okay, and BP higher that I would like but still acceptable so I don’t worry. I might do a cardiac doppler exam I few months just to be sure my left ventricle isn’t getting bigger because of the adrenergic stimulants and androgens.
I going to order lactoferrin and more iron to try to increase ferritin and RBC before it became problematic. It always has been a problem for me and in my family in general. We definitely don’t have the hemochromatosis gene lol
May increasing my DHT level by stopping finasteride improving my androgen status help to stimulate my bone narrow making more RBC?
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You should go up by 2.5mg increments at a time, this is what is recommended.
I don’t feel constipated using tirzepatide. I did get nausea going from 2.5 to 5, but the 2nd shot at 5mg didn’t cause any nausea. I certainly need to remember to eat though haha.
I’m getting pretty lean, I’m really trying to lose visceral fat. I see some veins popping in abs even after doing exercise which is cool. Arms got lots of veins too now. Even got a cool vein in my shoulders.
Tirz + TRT is a nice combo for body composition.
Smart to check, but something to keep in mind is GLP1s and tirzepatide in particular have been shown to stop ventricular hypertrophy. Keep me updated with how this exam goes.
Evidence that tirzepatide protects against diabetes-related cardiac damages: “Our findings indicate that TZT has beneficial effects on cardiac cells by positively modulating cardiomyocyte death, fibrosis, and hypertrophy in the presence of high glucose concentrations. This suggests that TZT may reduce the risk of diabetes-related cardiac damage, highlighting its potential as a therapeutic option for heart failure management clinical trials. Our study strongly supports the rationale behind the clinical trials currently underway, the results of which will be further investigated to gain insights into the cardiovascular safety and efficacy of TZT.”
Tirzepatide Reduces LV Mass and Paracardiac Adipose Tissue in Obesity-Related Heart Failure: SUMMIT CMR Substudy: “The CMR substudy of the SUMMIT trial demonstrated that tirzepatide therapy in obesity-related HFpEF led to reduced LV mass and paracardiac adipose tissue as compared with placebo, and the change in LV mass paralleled weight loss. These physiologic changes may contribute to the reduction in heart failure events seen in the main SUMMIT trial. (A Study of Tirzepatide [LY3298176] in Participants With Heart Failure With Preserved Ejection Fraction [HFpEF] and Obesity: The SUMMIT Trial”
Tirzepatide attenuates lipopolysaccharide-induced left ventricular remodeling and dysfunction by inhibiting the TLR4/NF-kB/NLRP3 pathway: “In brief, tirzepatide attenuates LPS-induced left ventricular remodeling and dysfunction by inhibiting the TLR4/NF-kB/NLRP3 pathway.”
Effects of tirzepatide on circulatory overload and end-organ damage in heart failure with preserved ejection fraction and obesity: a secondary analysis of the SUMMIT trial: “Tirzepatide reduced cardiac injury, reflected by decreases in troponin T, and reduced wall stress, reflected by decreases in NT-proBNP”
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I see that your ASAT and ALAT have gone from 20’s to 80’s to 40’s over time, do you think this is due to the supplements you are taking, or is it from getting blood work shortly after training?
I ask because I have also had a similar thing in the last few years, from 20’s to 40’s so from low normal to high normal, and I can’t quite figure out why. I don’t think it is supplements for me because I don’t take a lot, and it might be training because I train quite frequently, but difficult to isolate because I have always trained when I get my blood drawn!
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I think it’s due to training mostly. When my transaminases where in the 20 range, I was below 60kg and didn’t weight training, so I had basically no muscle and no muscles destruction.
Now I train pretty hard and I’m always sore somewhere and usually in few muscles at the same time, sometimes badly (leg day with trap bar deadlift for example), some my muscles leak transaminases in my blood. That’s my theory knowing that every othe 100% related liver marker look great : GGT, bilirubine, alkaline phosphatase. I don’t worry about my transaminases now, unless if someday they go up in a really concerning level.
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Fair enough. I had no clue you had past issue with obesity. It’s cool you shared here.
That is pro level fat burner combo targeting different areas with the alpha + beta receptors.
Good idea to make sure left ventricle is not getting bigger.
Cool, hope the lactoferrin works. Ya that’s odd it is a problem for you and your family.
I don’t know if DHT boost would improve the iron. Never heard anyone mention that before.
Keep finasteride if your testosterone levels are that high. Save your hair, and prostate.
Various medications used for anemia sometimes are nandrolone, anadrol, and others.
Maybe consider taking the iron pill 2 hours after coffee or calcium food (milk/yoghurt).
Some people take iron pill with or without food.
I’ve seen more people have issues low iron issues drinking coffee or teas, and high calcium diets than DHT levels.
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I’m not sure this is really longevity target to be honest, no offense intended, but you might have different goals.
Longevity I think of a slow turtle in Okinawa eating mostly sweet potatoes and not ramping up mTOR a lot nor is super lean, or a lot of steroids and other drugs. You might not have drug interactions but it’s hard to tell what all of the drugs are doing. If you didn’t take a lot of drugs maybe your longevity markers would be the same. Mike Lustgartens avoids all drugs and supplements as he doesn’t want to be the guy who “took too much” and made a mistake.
The people in the Blue Zones are way more informative (with added pharma help to keep things in check, of course), in my opinion, and they’re not too lean but CR has probably many benefits.
Body fat I think healthy levels are 10% or above.
But whatever you feel is best is important, relatively speaking e.g steroids are much safer than other drugs. But do keep people updated, it’s interesting to see what other people do!
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Hello
It’s definitely not 100% longevity targeted because if it was I wouldn’t take testosterone for sure, and not at this dosage, I wouldn’t take either metabolic enhancing molecule like salbutamol/mirabegron. I would be following a vegan diet and doing some stuff in some other way.
My main goal is to live long while being able to do what I like to do, and be here for/to know my future family. I don’t want to live 100 years and being 10 years in a wheelchair with dementia. Mainly, I want to love my life. And that’s the hard part lol.
I like to look great, and be muscular. Anabolic steroid, especially testosterone, is useful for this goal. Like every drug/supplement, is has downsides and benefits. Downsides are almost non existant at low dose. It’s basically non toxic. - even if there was an accute toxicity, it is 100% reserved by what I doing-.
Muscles are a great proxy for longevity. I think I’m doing great, and I don’t know if you’re American but a lot of people are taking the dose I take for life as a TRT and not as a"bodybuilding cruise".
I know some of my biomarkers before, and these were okay but not that great : my natural LDL-C is 85mg/dL more or less for example. Right now everything is pretty solide exept my iron statut. I’m working on it - I’ve juste received my lactoferrin, I’m going to take 800mg on an empty stomach-, and increase my Ferrochel dose to 36mg, empty stomach too-.
Also, I take some drugs for the long term benefits, like sglt2-i. I believe it is a long term investment.
I agree however that some of the drugs I take might not be useful like the ones I take to sleep, definitely not toxic, but just useless longevity wise. And these doesn’t help my biomarkers neither, their job is to make me restful when I woke up.
I would like to finish with the fact that I consider myself a guinea pig. Kinda. I try to do things right, but I like to experiment, and see what happen. Pharmacology is really something I like. So I try, I observe, I change, I improve, and see how it goes. Then, usually, I post here. 
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It’s ok, we all have different goals and priorities, and like I said, it’s not that bad relative to other drugs, and I don’t know what it means what you’re on.
I was going to take steroids but I saw someone said to wait until I was 25 years old. Then I didn’t care about my physique, and to be honest, I don’t think other people do either that much (unless in the more extreme), or this might be copium.
I like Avi Bitterman and he’s on gear + plastic surgery and has gender (masculine euphoria), and it’s probably not even that much of a longevity detriment if done appropriately, lulz.
Indirectly longevity/health related (and testosterone can of course be that as well).
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Cocoa powder? Nah…
Pure dry beef blood. It’s sold as dog food. 28mg of heme iron per 10g. Should level up ferritin fastly.
I’m going to try a few grams a day with meals (don’t want digestive issue). It smells like fish food. Not that bad.
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That lines up with my thinking too.
Back when mine were in the 20s, I wasn’t lifting nearly as hard or as consistently. Now I train with decent volume and intensity, and usually test within 24h of a session—sometimes even same-day. And like you, I’m lifting 4–6 days a week and usually sore somewhere. All my other liver markers (GGT, ALP, bilirubin) are solid too, so I do also suspect muscle leakage is the main driver.
BUT there are a couple things that still make me second-guess it:
• ALT is supposed to be more liver-specific, so if it were purely muscle-related, we’d expect AST to be higher and ALT to stay lower—but like yours, both of mine sit in the 40s.
• There’s some literature suggesting enzyme elevation post-training is more common in untrained individuals, which doesn’t exactly fit our profiles.
The only way to know for sure would be to stop lifting for a full week and retest… but I’m not sure I can pull off a no-lifting week haha. I wish there were another way to know—some marker or ratio that could give us clarity without needing to pause training.
Thanks for sharing. That’s the question. I guss having a very high low cholestrol and/or using drugs like statin causes more muscle damage, yielding high transaminases?
| Drug I take : | Dosage : | Why ? |
|---|---|---|
| T4/T3 | 100/20µg a day | Hypoactive thyroid |
| Testosterone undecanoate | 150mg once a week | Ultra-low free T |
| Tirzepatide | 10mg once a week | Weight and metabolic management |
| Empagliflozin | 25mg daily | Cardio and nephroprotective |
| Canagliflozin | 100mg daily | Cardio and nephroprotective |
| Telmisartan | 80mg daily | BP |
| Cilnidipine | 5mg daily | BP |
| Nebivolol | 5mg daily | BP |
| Mirabegron | 100mg daily | Metabolic management |
| Salbutamol | 20mg twice daily (40mg) | Body recomposition |
| Finasteride | 5mg daily | Skin antiaging, BPH and hair loss prevention |
| Modafinil | 100mg daily | Energy and focus |
| Ezetimibe | 10mg daily | Cholesterol management |
| Bempedoic acid | 180mg daily | Cholesterol management |
| Pregabalin | 50mg daily | Sleep |
| Trazodone | 100mg daily | Sleep |
| Pitavastatin | 4mg daily | Cholesterol management |
| Melanotan II | 1mg daily | Cosmetic enhancing drug |
| Eplerenone | 50mg daily | Lower sodium retention due to higher estradiol level (high T, low DHT) |
| Tadalafil | 20mg daily | Vascularity |
My current protocole. Huge list, I know.
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That’ll do it. I’m happy with 5mg 4x a week.
Do you ever take breaks on that one? I find it interrupts sleep.
Just curious how you are feeling generally on all of this?
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