Holy moly! I can balance on one leg on a Power Plate for five minutes changing positions every minute, but 12 minutes on my toes, plus your additional dental gymnastics, would be impossible.
Your weekly routine seems to cover absolutely all the bases and then some. I wish you luck maintaining that level of activity well into your 70s and beyond!
I do a mixture of resistance training and cardio. Typically will be 6 different resistance stations such as bicep curls, bench press, back resistance, tricep resistance, pull-ups for example. Then 17-20 minutes on a stationary bike with varied resistance or similar on an elliptical machine. Will get heart rate up to around 150 BPM during cardio portion.
I’m not sure why you’re so certain about your conclusion. Intuition alone tells us that exercise must increase the maximum lifespan of mice—exercise is literally the single least questionable intervention in the world.
The moderate exercise provided by weakly treadmill training starting at 28 wk of age increased mice survival; median life span was increased by 19 and by 9% in males and females, and maximal life span was increased by 15-21% and by 8-17% in males and females. Exercised males exhibited a 29% increase in the fraction of animals showing longevity
I see you are new to this subject. That’s OK. Everyone is new to any subject at some point. But here’s a pro tip: before engaging in a discussion, it is more useful and illuminating if you first get a good grounding in at least the basics.
As to the study you posted. I assume that this time, unlike other times, you read the study you posted. Since you read it, it can only mean you are very, very new to the topic, otherwise you wouldn’t have posted it with the commentary you did.
From the study you posted - quote:
“Mice of the CD-1 strain[…]”
And you can stop reading there. Done. The study has no relevance to your commentary.
Given your comment, I can see you literally need to start from a 101 level. Since the subject is so vast, I cannot possibly provide you with that grounding in a comment section on a website. You need to do that education yourself.
If you need to track down the characteristics of CD-1 mice, here is a precis:
Basic Characteristics & Common Applications of CD1 Mice
Quote:
“CD1 mice and C57BL/6 mice differ in the aging process, experimental operability, and genetic application scenarios. The median lifespan of CD1 mice is 18-22 months, shorter than that of C57BL/6 mice (24-28 months). CD1 mice are more likely to develop age-related diseases like cataracts.”
Key point of this is something that you should have already absorbed, and which you clearly did not - hence you need to start your exploration of this subject at the very basic level:
The impact of short-lived controls on the interpretation of lifespan experiments and progress in geroscience – Through the lens of the “900-day rule”
https://www.sciencedirect.com/science/article/abs/pii/S1568163724003301
It’s a fascinating and vast area, so happy study! When your commentary reaches levels rewarding discussion, I’ll be happy to engage, but until then I have to bow out.
How often do you report new research in rapamycin? It seems the feel is moving far faster.
I report it whenever I see a paper… I may not report on studies that are focused on c.elgans (worms) because they are too far from humans, or that are focused on off-topic areas (there are frequent studies on stents coated with rapamycin for example).
I have many suggestions for pertinent topics in this field.
Have you seen the research on low-dose naltrexone?
What is your opinion of the nay sayers of rapamycin slowly adjusting their opinion?
Edit your previous post instead of posting new ones. Press the pencil icon. Otherwise @RapAdmin should enable the function again that disables multiple posts in a row IMO, it’s an eye sore.
Point taken sorry about your eyes
Haven’t heard much from anyone on low-dose naltrexone.
The human metabolism is one of the most complex biological systems in nature. As we reach 70, our lifestyle choices have reached critical importance. Learning to balance caloric restriction with exercise becomes in my opinion the greatest challenge to those that want to extend a healthy happy existence.
Strategic eating, focusing on nutrient dense foods has been an outstanding strategy for me. I don’t keep track of calories. I have a list of foods I eat every day in my 3 to 6 hour window. these include avocado, broccoli, sprouts kale, walnuts, blueberries, creatine, 1/2 a beet a tofu hash, which includes mushrooms, spinach, bell peppers, onion, garlic. I finish my day off with coleslaw and black beans. After that, I allow myself anything else I want in my window less than once a month do I actually eat anything else. I do admit I have to work at keeping my weight up.
Super healthy foods choices there. That eating pattern will definitely support longevity and health span.
I don’t know how long you’ve been on this forum, but low-dose naltrexone has been a subject of keen interest here for almost four years. Check before you post.
I’ve been taking LDN for years
Low-dose naltrexone needs to be nominated for the intervention testing program. if anybody knows Rich Miller, ask him why he hasn’t.
Just out of curiosity, has anyone heard the research on C 15. Apparently it’s a molecule found in dolphins that block 10 of the 12 pathways of mtor. Apparently rapamycin blocks all 12.
BTW, Tim was your post to me to read before I post a suggestion or a demand? Sorry if I’m not up on past discussions I am a new member and technically challenged