Lada Nuzhna and A New Bid To Control The Genome

It makes sense to not be hand wavy about “AGI superintelligence in 20-30 years leading to LEV in 30-40 years”, and it is way more scientifically rigorous to not assume the AGI will fix longevity route, but it is probably where most of the probability mass is (even then the uncertainty range is pretty extreme and the only relevant number is whether or not it’s above or below 50 for reasons - which also has a large probability mass on how AI will enable levels of empowerment that make it easier to destroy everything AND on exponential microplastic growth step function-accelerating everyone’s aging rate at some point in the future ((1)))

It’s better for many longevity researchers/entrepreneurs to not swallow the “AGI superintelligence in 20 years determines everything” pill (but there is definitely substantial probably mass on this). Longevity researchers don’t know AI well enough to make rigorously epistemic claims about AGI timelines so it is intellectually responsible not to hedge most of one’s probability on superhuman intelligence

But let’s just say that despite the limitations of transformers and scaling, this year’s AGI progress has been enough to surprise some skeptics like chollet. Karpathy has 10 year timelines. Ilya has timelines within 20 years

Keep in mind AI researchers were wrong about timelines in the past, but something is very different now

Superhuman persuasion may at some point influence the regulators…

((1)) A trainer has already said he’s seeing their effects in athletes. Also bison meat from Montana is cleaner in MP load

The real dark horse is how Chinese biotech is growing way faster than American biotech (this also significantly changes the percentages). Chinese have way fewer hangups about many kinds of biotech regulation than Americans do (just listen to Xi Jinping), and maybe nothing will impose more pressure on America to deregulate than the possibility of losing to China

1 Like

When I read about Lada Nuzhna, I’m always struck by the sheer improbability of the story. It’s captivating. And honestly—who wouldn’t be intrigued?

After all, would elite donors really pour millions into someone whose name translates, quite literally, to “A Mercedes Needed”?

Let’s transpose this into a Western context.

Imagine a 22-year-old arriving on the scene with:

• No college degree
• A vague or patchy biography
• No academic publications
• Minimal professional track record
• And a name that reads like a punchline: “A Mercedes Needed”

…and then raising $34 million in philanthropic funding.

That would be, by any conventional standard, extraordinary.

Most high-net-worth donors—especially those allocating millions—rely on rigorous filters: background checks, reputation audits, credibility assessments. But in certain ecosystems, those filters soften. In fact, they sometimes vanish altogether.

In niche domains like:

• Crypto
• Effective altruism
• Thiel Fellowship circles
• Longevity “moonshot” funding
• Silicon Valley “talent arbitrage”
• Ideologically driven philanthropy

…the rules shift. Traditional credentials take a back seat to charisma, vision, and the right introductions.

In those rarefied spaces, someone with an improbable name can still raise capital—if they:

• Have access to the right backers
• Are vouched for by trusted insiders
• Embody the “outsider genius” archetype
• Exude confidence and master the art of narrative

And that’s where Lada Nuzhna fits in.

Despite the headlines, very little is publicly known about her early life or how she made the leap from “teenager in Avdiivka” to “multi-million-dollar grantmaker in longevity science.” The available information is sparse—just a few narrative fragments. Beyond that, we’re in the realm of speculation.

What We Actually Know

Origins and U.S. Move

• A 2023 profile notes she “grew up in Avdiivka, a war-torn city near Ukraine’s border with Russia,” and left for the U.S. at 18 “in hope of understanding the mysteries of the universe.”
• No details are provided about her high school education. (In Ukraine, students typically graduate at 17.) Avdiivka (Donetsk Oblast) is classified as a city, but its population—around 30,000 before the war—makes it more comparable to a small town by Western standards. Given the war and occupation in Donetsk Oblast since 2014, any local educational institutions—if they existed—would have been severely disrupted or relocated. Most likely, by the age of 18, Lada’s education was limited to high school.

Education in the U.S.

• Multiple bios (Federation of American Scientists, The Institute, Springer/Impetus) state she studied physics and computer science at Northwestern University before dropping out to pursue biology and longevity research.
• Her own site echoes this: “Before dropping out to pursue my research in biology through Thiel Fellowship, I studied physics and computer science.”
• There’s no public record of how she was admitted—no mention of high school credentials, English proficiency, standardized tests, or preparatory programs. For a selective U.S. university, she would’ve needed to demonstrate strong academic and language skills, but the specifics remain undocumented.

Impetus Grants & the $34M

• According to her website, she “started and runs Impetus Grants,” having raised and allocated over $34 million to aging-related projects in roughly four years.
• A recent feature on her new venture, General Control, notes that Impetus was backed by prominent pro-science philanthropists like James Fickel, Jed McCaleb, Juan Benet, and Vitalik Buterin.
• The official Impetus site lists her as a co-founder alongside Martin Borch Jensen and Juan Benet.

The Bottom Line

Yes, “Lada Nuzhna” does translate to “Mercedes Needed.”

And yes:

• It’s unusual.
• It’s unforgettable.
• It sounds invented.
• It invites scrutiny—of identity, authenticity, and origin story.

“Nuzhna” (Нужна) is only a Russian word — not Ukrainian. In Ukrainian, the word “nuzhna” (feminine) is:“потрібна” (potribna)

So a Ukrainian native surname or phrase would never be “Нужна,” because:
• “нужна” is not used in Ukrainian
• It is pure Russian grammar and vocabulary
• Ukrainian and Russian have clear differences in adjectives like this

Thus:

The name (or phrase) “Лада Нужна” is linguistically Russian, not Ukrainian.

If someone were Ukrainian and had such a surname, it would be extremely atypical — almost like a French person with an English adjective as a surname.

Names shape perception. They signal culture, credibility, and context. And by any linguistic standard, hers is not a typical Slavic surname. Not even a Ukrainian name. It’s phrase or a short sentence in Russian.

But in the right circles, the improbable can become inevitable—if the story is compelling.

So I continue to be fascinated by this highly unusual and curious case. The whole longevity domain often looks like a dot-com bubble. The comparison isn’t perfect of course - there is real science happening in longevity, and some projects are deeply rigorous. But the funding dynamics, founder archetypes, and narrative inflation feel eerily familiar.

3 Likes

Yes, I’ve been reluctant to express any opinion on Lada here, as there are two opposing instincts battling for my brain. On the one hand I am an optimist and I tend to be very generous in extending the benefit of doubt to anyone involved in the longevity field who appears to be passionate about this subject, and I certainly am willing to allow for extraordinary events and people and improbable origin stories. Then there’s the other hand - I cannot help the powerful feeling of “too good to be true” and “social engineering scam” vibes. There’s too much that just doesn’t add up.

But. But. But. Ultimately it’s the results that count. Are we going to see anything concrete come out of her activities? If yes, then OK, let’s accept the “meteor strike” type miracle of what led up to this. But if not, well, more and more questions will be raised as time goes by with nothing to show for it except for evaporating funds. This may or may not unravel particularly rapidly.

The fact is, that even very legitimate efforts by legitimate scientists and leaders in the longevity field tend to come up a cropper. How often have we seen successes from anything where billions were poured into biotech ventures by even large companies like Google (Alphabet), Tornado and so on endlessly. The track record is dismal. There’s failure after failure. We keep hearing promises about breakthroughs in the near horizon, to the point where it’s become a meme, like the perpetually 5 years into the future of AGI, quantum computing, fusion, curing cancer and so on.

Yeah, right. I’m sure some of these “investment opportunities” are legitimate and have sincere people behind them, but in my experience (being old means you tend to become cynical), the majority (yes, I said majority) of these are designed to score some cash on yet another hype cycle, whatever the current hot media frenzy throws up. No progress is made as none was planned, but some people make out like bandits (see: David Sinclair). The story is as old as time, and frequently annotated like the Pied Piper one: a stranger turns up nobody knows from where and leaves with all the kids.

Also, this is a deeply cynical environment. Don’t get too attached to whoever the backers are. Just because there’s a backer doesn’t mean they put the money in because they believe in the project and are risking their own cash. Often it’s just an early “investor” who comes in at the early stage of a Ponzi scheme and hopes to pull out with more cash than they put in. So they’ll advertise widely their faith, investment and do the introductions of opportunity to the real “sheep to be shorn” later investors using their early investment as providing confidence. So they can work completely cynically just backing a smooth talking “enterpreneur” who can spin a beautiful story and then they cash out.

OK, so I know nothing about this person. I hope for the best. I hope I’m just an old cynic who will soon be proven wrong. Why not? I’m a motivated “buyer” of such stories, because I have an obvious interest in prolonging my own time on this earth, so I’ll be super happy to find a unicorn. That said, well, statistics tell us unicorns are rare. Very rare. Very, very rare. I hope this one is just such a miracle. We’ll see, fingers crossed :crossed_fingers:!

1 Like

Lada Nuzhna was accepted for Thiel Fellowship. One of the requirements is to drop out of college. Only 1% of applicants is accepted! Looks like she’s a talented and lucky girl! I also hope for a miracle.

The following was AI generated.

The Thiel Fellowship is a prestigious two-year program that awards $200,000 to young people under 23 who want to build startups, conduct research, or pursue bold projects—instead of staying in college.

:brain: What Is the Thiel Fellowship?

• Founded by: Peter Thiel (co-founder of PayPal, early Facebook investor) in 2011
• Purpose: To support young innovators who want to skip or drop out of college to pursue ambitious ideas
• Funding: $200,000 over two years (no equity taken)
• Support: Access to a powerful network of mentors, founders, investors, and scientists
• Cohort Size: ~20 fellows selected annually
• Location: Global — no relocation required, though many fellows operate in tech hubs like SF or NYC
• Focus Areas: Startups, biotech, AI, crypto, social movements, scientific research, and more

:white_check_mark: How to Qualify

There are no formal academic requirements, but successful applicants typically show:

• Age: Must be 22 or younger at the time of application
• Academic Status: Must be willing to drop out of college (or not enroll) to accept the fellowship
• Vision: A clear, ambitious project — startup, research, or innovation — that you’re already working on
• Progress: Evidence of traction, prototypes, or early results (not just an idea)
• Independence: A strong drive to build outside traditional institutions
• Narrative: A compelling personal story that signals grit, originality, and long-term potential

:memo: Application Process

• Rolling admissions: You can apply at any time — there’s no fixed deadline
• Application includes:• Personal background
• Project description
• Evidence of progress
• Optional video or pitch deck

• Interviews: Shortlisted candidates are invited to interview with the Thiel Foundation team
• Selection: Highly competitive — only ~1% of applicants are accepted

2 Likes

I turned her into a Thiel Fellow… (though it was really many many conditions [+a long chain of events] that were jointly necessary, none of them sufficient). I at least was the impetus (though the grouphouse+super long-list of intros I made were also super-impt).

((The grouphouse also only existed due to me)

[getting a thiel fellowship is extraordinarily competitive - like <= 40,000 applicants - it takes a lot to turn someone into one, and many many things have to jointly go right and some of the decisions made last-minute are extraordinarily borderline]

…my interactions with her in that year of 2021 (as well as everything else that happened that year) probably are and will remain my peak life experience… [2021 remains the best year ever and nothing other than AGI will change this]

==

[much later on, she once made a tweet on how facilitating serendipity is a viable “alternative”…]

==
I think her coming from the Donbas is quite relevant, esp b/c all the chaos tends to force some people to be less traditionalist (and sometimes forces some degree of neurodivergence onto the entrepreneurial)

1 Like

@AlexKChen, why in particular did you see her as a ‘diamond in the rough’ ~5 yrs ago?

It’s still hard to describe. Some energetic pathways are hard to make legible. Kanjun qiu (VERY progress studies aligned) often mentions how legibility is overrated… (It’s smg rationalists are way more into)

But legibility can make some things feel more fair…

I remember that back then she had a protein folding project with a fellow northwestern friend named karina (also immigrant from the former eastern bloc).

It’s important to note that coming from Eastern Ukraine to the US gives you a “jagged frontier” of capabilities bc your development is chaotic/uneven and you didn’t get the cultural enrichment/“privilege” or gifted programs others got early on. But you also don’t get exposed to much of the cultural noise and assumptions (including wokism) that people in the broader anglosphere were exposed to (and the broader anglosphere basically includes all of Western Europe now)

She learned English late so this also continued to a jagged transition during her time at northwestern.

In other words she came to the States as a teenager after high school (if she even graduated - it was a war zone) who hardly spoke any English and then got lucky to enrolled in Northwestern and in 4 years managed to collect $34 millions and now advises the biotech world in what direction to take - am I right? It’s a great story!

1 Like

Let me guess… is she hot? But seriously I hope for the best. The story is pretty incredible, and unbelievable, and both those words can be understood in various ways. YMMV.

I wish she posts her bio for “old” skeptics like you and I not to have any suspicions. Why not to be transparent? Theres much interest about her. Ppl want to know the details of her miraculous ascending.

1 Like

It has worked out well for longevity thiel fellows in the past to have a mystique around them. Sometimes it works better if you know less so you can give higher fat tail probabilities to them

Sometimes it works better because you get the world to adapt to you rather than the other way around, and distributing funds is the first way to make this happen

Like some of them have been described as complicated and unknowable

The less ordinary they seem and the more “alien in them” they seem, the more willing ppl are to give them a chance even if they appear illegible at first

(Messy backgrounds are one way to do it, being unschooled is another, having a super fast growth trajectory is another

I have realized myself that it’s often better to say less than more especially if people initially give you benefit of the doubt

There were 4 people I set on exponential growth trajectories that year, often for not entirely legible reasons, much of it was network luck. My network that year alone was uniquely powerful.

But also much of it happened because one person important to me also created hyperstitions that worked really well that year (fueled manic energy that accelerated multiple people.

Though that level of hyperstitioning also led to maybe too much of that manic energy the following year (that turned into temporary LLM psychosis - they egged on the manic energy a bit too much)

If someone sells snake oil it could be a great tactic. Otherwise why to play games?

We need Longevity Billionaires.