Hello all, Im really happy I find this amazing site!
I wanted to start Sirolimus yesterday (Pfizer 100x1mg), but drug interaction checker scared me a lot! I take several drugs on a regular basis, with which it seems to react seriously:
hydroxychloroquine sulfate + sirolimus
hydroxychloroquine sulfate and sirolimus both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
sirolimus + pregabalin
sirolimus, pregabalin. Either increases toxicity of the other by Other (see comment). Avoid or Use Alternate Drug. Comment: Coadministration results in additive risk of developing angioedema of face, mouth, and neck. Angioedema may result in respiratory compromise.
Anyone use same drugs as me and use Sirolimus despite it? Any experiences and opinions?
I would love to try it for my severe ME/CFS! Probably 2-4 mg 1x week. But now I’m scared.
thank you RapAdmin, I know most everyone here is using rapamycin for anti-aging benefits, but maybe its possible that they also Pregabalin and Plaquenil, because these are relatively common drugs
Great point with calling doctors from Rapamycin list! thx, I will try it.