When i lived and worked in china, my distilled drinking water came in a big plastic bottle for the dispenser.
I bought a tds pen to test every bottle.
I worked for a govt agency but even then i was aware over 50% of drunking water was fake and the delivery guys often swtiched it for a profit.
I saw colleagues went to the icu en masse after a company event catered food led to food poisoning (they tried to cover up).
I even saw a fake water factory basically just a factory with taps and rudimentary filters and farmers squatting on the floor sticking bottles to the taps.
I was so traumatised by my experience living there i nv went back even for holidays again.
Horrible place to live in especially for health concious ppl.
I dont even buy any MIC food till date regardless whethwe its apple or fish
u can buy many drugs OTC or online in China that you cannot in the US or a developed country
its the wild wild west there in terms of medicine and drugs.
the big companies are usually reliable
covid leaked from gain of function research at the wuhan lab…its not the first time anyway…sars leaked previously in beijing but luckily it did not spread like covid…
there was a shenzhen doctor who did some live gene editing or cloning recently
as for their ‘trials’ 99% are substandard and faking data
This is exactly true. China has some great companies and great suppliers that lead their industries, just like the USA or Europe.
But it also has thousands of shadow companies (and a million middlemen) that sell all sorts of low quality chemicals and medicines. If you’re buying from the top tier of manufacturers you are likely fine. But with the Peptides and other non-standard products it’s the Wild West.
And the U.S. is losing its lead in scientific research. American universities have long dominated world rankings, based on the quantity and quality of their research, while a Chinese school would have rarely made the top 25. Now that script has flipped. Today, according to the Leiden Rankings, a prominent global ranking center, eight of the top ten schools are Chinese.
Well, you might have a point, but it would be worth mentioning there have been schools in Europe that rank in top 20 for a long time, and Europe’s economy (as well as business and scientific research) is nowhere near that of USA.
Not worried that we will lose to anyone out there (anytime soon). In 100 years from now, who knows but certainly we’ll do just fine in next 20 or so. I’m old enough to remember when everyone was saying that Japan will eclipse USA and become the biggest economy in the world (that was in late 80’s) and the opposite happened. Japan’s GDP in 1994 was $4.6T and USA’s $6.7T. Today Japan’s GDP $4.2T and USA’s $35T. Basically Japan’s economy was 70% that of the USA’s. Today, Japan’s economy is barely over 10% that of USA.
I think the practical issue having this on the manufacturer of “Research Peptides” is they will produce a certified analysis for a batch … but, very easy to fake, and who knows what they are actually sending you.
https://www.finnrick.com/ is interesting as folks are sending them batches to test and they report on them. Their testing isn’t as extensive as what you list, but is indicative. They look to only be testing 6 different common peptides right now, but looking through their results, there are certain groups that look better than others.
The most frequent issues that yield a bad score end up being the amount listed in the vial to be different to some extent from the amount in the vial (often there is more than labelled); but purity seems really good on most that I look at, including the ones not rated well. Endotoxins are test, but metals and other items aren’t as far as I can tell.
I have heard of groups of consumers that end up crowd funding and test a batch with every person paying their share and when it tests well, then they buy it once its quality is confirmed.
I’m just not sure in this area we can trust the supplier to supply the testing result with a sheet from a “third party tester.”
I’ve got a lot of patients who use “research peptides” and I’m yet to see anything adverse occur, and I think most are the real thing and probably reasonable on purity. I however have a disclaimer for my patients doing so, and let them know, it is safer for me to advise them on use of peptides than have them go on their own, but when they are purchasing these “research peptides” I have not way to assure quality and this risk is on them for any adverse outcomes.
So - are you saying that typical purity tests that are being done by RP-HPLC (Reverse Phase High-Performance Liquid Chromatography) + MS (Mass Spectrometry) are not something we can trust?
Should we have much less confidence that, even with a “purity” test suggesting that there is a measured mass match (I’m assuming this is compared to a reference standard) - we have no idea if the amino acids are in the correct sequence?
Actually, Janoshik COA reports contain a serial number at the bottom that can be pulled directly from their site it validate that report. Buyers have learned that no serial number then high likelihood of it being fake. That doesn’t preclude sending the good vials to be tested, but fakes to customers. That is why most buyers will not trust new vendors without a history of true 3rd party testing group validation.
That’s one of the things that "testing: does not reveal. Some tests do not reveal the assay, how much of the active peptide is in the total amount of powder.
Our mfg does provide this information in their COA’s
When I had some of ours tested 2 years ago, it showed that the 'tides (Reta and Tirz) were about 90% assay, while that 90% was >98.5% pure. This matched our mfg COA’s.
As you have noted pure what? With 'tides we see the physical result and it’s easily measured when people step on the scale, we know the peps are doing what they are intended to do.
One aspect of this is, if you think you are using 5mg in a single shot, with 'tides it many only be 4.5mg and this becomes a bigger factor as the dose goes up. So we compensate for that.
With the other peptides we have tested most had a 96%+ active ingredient.
Then people always ask what is the other 10% - 4% LoL!
There are definitely valid questions on “where to draw the line”… and I suspect its going to be an Individual thing (though a different question for a longevity type clinic that Matt is running now).
On one hand, I understand why many medical professionals wouldn’t want to touch these with a 10 ft pole, but on the other hand, the rules are keeping many from getting the help they need (someone morbidly obese without good insurance not being able to get glp1’s is a perfect example).
And then there are more fringe cases. I’m a great example. SS-31 is proving life changing for me, but I could still be perfectly healthy without it. At this point, I’d break all sorts of laws to keep my supply coming.
If doctors stay clear of the topic, it forces their patients to go completely rogue. My doc, even if against me getting anything grey, is open minded and I can discuss it all with him. I think I’m safer if he knows what I’m doing, but unfortunately, most people have to keep what they are doing a secret… and ultimately, that is worse for their health.
To the best of my knowledge, if getting any of these things compounded, they are getting the same product we can get on our own. Is this not true? Is there some fda regulated factory supplying compounding pharmacy with the raw materials… I’m thinking not, but I’ve never asked the question.
The AI text fingerprinting is easy to spot. For me it makes me think its a AI statement and not Kaeberlein’s own. (Even though I know it’s the latter.)
I’ve shared this in the ss-31 thread but unless it’s a crazy coincidence, it’s doing two drastic things for me.
My biomarkers are great, but my abnormally high glucose spikes have always been an issue. I take things to improve them (dapagliflozin/acarbose), but I would still shoot through 140 many days per week. It appears that is all a thing of the past, so much so, that I’m now reducing my acarbose.
And more useful is my ADD seems to have vanished. It was never bad, but I’d have trouble finishing boring tasks or being able to focus on things that I didn’t enjoy, etc. I can no longer even detect I have it.
Dang! you are almost convincing me to part ways with $300 as I had promised myself, I’ll never touch a peptide again. Thought I’d tried SS31 already but checked my stash and it isn’t there so I’m very tempted to try. While what you are saying seems pretty good it is still a bit subjective. I was hoping you’d say something more to do with substantial increase in energy level plus better sleep as an example.
If I decide to go for it and I find it is snake oil, then I’m allowed to hold a grudge against you LOL. I’ll wait till tomorrow and see if I still want to buy.
In addition to above @Beth can you also share who did you buy it from? I see QSC having it in USA warehouse 50mg for $300 (tested a bit lower quantity though, more like 45mg but still good pricing) but since you feel it’s working for you, at least it means you got the real deal.
I’m taking 4.5mg 4-6 days per week… I skip for no other reason than it is expensive and I’m trying to stretch my supply, and of course sometimes I’m just lazy. It doesn’t seem to matter.
I randomly chose 4.5 because Hazel is using 5mg daily under her tongue, so I figured I could have a little less due sub q being more readily absorbed.
@Kelman I got mine from pgb … if I recall, it is 25mg for $215, but it’s really 30mg… and I spent 300 to get free shipping… at that point is was close or better than QSC, and if close, I’d rather buy from them
My sleep is already great. Focus and ability to complete tasks might translate into more energy but that is too hard to tease out… am I getting more done due to energy or just that I’m focused and motivated to finish my tasks… I dunno ?
