How to Reverse Skin Aging

How frequently do you use the device in a given area? And what was the total US$ cost of the product plus shipping?

How does it compare to any other approaches to skin care, skin rejuvenation, etc. you may have tried?

How long does it take to use? What are the side effects (does it hurt?, leave your face red for a while, etc.?)

4 Likes

I am also curious how it compares to microneedling, since both are essentially the same principle of creating temporary microchannels and stimulating dermal repair. Tixel does it with fancy heating. The needle just shoves a piece of stainless steel into your skin.

However, a good microneedle pen setup gets you accurate depth control, different speeds, lots of different needle sizes and coverage areas, and costs like $200. I’ve self-administered maybe 7-8 sessions so far, and I think it works really well. I’ve also extended it onto my hands, arms, trying to repair sun spots etc and I believe it’s working.

2 Likes

I’ve seen some doctors claim a dermaroller is safer and as effective as a microneedle pen. The roller prevents dragging the needle through the skin causing unnecessary damage.

I’d be interested in seeing a study comparing Tixel to microneedling.

1 Like

How often? I hit the same area about once a 6-8 weeks. That break gives the skin time to close up and start making fresh collagen. New collagen starts forming right away, is busiest in weeks 2-4, and keeps building for roughly three months according to studies - so treating again after ~4–8 weeks lets you layer the benefit without over-doing it.

Price of device was 1400 euro and price for delivery and custom clearance was about 550 euro (Incoterms: DDP Germany). In the meantime, you can buy device 300-400 euro cheaper.

How to compare it with other interventions? The biggest head-to-head study found that Tixel works about as well as a 1565-nm non-ablative laser around the eyes, causing slightly less pain but producing a bit more surface crusting. In broader terms, both Tixel and RF-assisted microneedling typically soften wrinkles by roughly 25–35 % - about one to two clinical grades - whereas plain microneedling alone usually achieves closer to 15 %.

How long does it take for 1 interventions and side effects. A full-face session lasts roughly half an hour. Higher energy settings can be quite painful, but a lidocaine cream takes the sting out. Expect the skin to stay red for two to three days, and keep it out of the sun during that period and afterward.

6 Likes

@relaxedmeatball and @SilentWatcher (or anyone else who has tried these)
@medaura … I know it’s new to you, but do you know?

I am curious about these.

My biggest skin issue is that I developed HUGE pores on my cheeks in my old age. I oddly don’t have little fine lines that are there when my face is at rest, but of course I do have wrinkles from movement that Botox addresses.

Do these gadgets work on reducing the look of pores?

(I do have a roller that I used twice, so I could find out for myself, but I worried it would be a lot of time spent for no result)

1 Like

This study briefly touches on Tixel’s effects on pore size. If I’m reading it correctly it did have somewhat of a benefit:

Results

The objective assessments demonstrated statistically significant improvements in the following parameters: roughness, wrinkles, pore size, elasticity, pigmentation, and erythema (p < 0.001). The FACE‐Q results demonstrated high patient satisfaction, with a response rate of 68.4%. The MAZDA analysis confirmed significant texture improvements across most facial zones, with the exception of the medial forehead.

This one also:

2 Likes

I don’t have Tixel but a lot of devices can help with pores. If that’s your only concern, the most cost effective solution is probably RF microneedling as the device costs around $300 and then consumables less than $10 per use, uses spread 4-6 weeks apart. I didn’t have problematic pores but some enlargement over the front of my cheeks and 0.1% tretinoin has been the most effective intervention for them. I noticed the pores looking much smaller in about a month of use.

@RapAdmin I love the results I’ve been getting from my devices, but yes, it’s never as impressive from a single treatment as what you see in the before and after images on Google for any particular modality under the sun. It takes 4-8 treatments spread weeks apart to really go wow and have people start asking you what you’ve been doing. It’s also ideal to have non overlapping modes of action. For example while I do have and use quite a few energy based devices (RF, tecar, ultra former / hifu, RF microneedling) I like now adding local dynamic micromassage and shockwave. Once a certain dial is turned up via controlled heat damage, you can’t do more without overtaxing your skin and probably more does more harm than good. But you can layer these others as they are independent of heat based denaturation of collagen. I’ve learned from people I know who perform treatments professionally that it’s often the folks with the worst baseline skin condition that get the most impressive initial results. Call it the catchup effect if you will. But once your skin is in very good shape there’s diminishing marginal returns that set in so it’s easier to go from skin score, if there were such thing, of 40 to 70. But much harder going from 90 to 99.

I think I’ll make a separate post about what I’ve got out of using devices. One thing I know though. You don’t need Bryan Johnson budgets to make it happen. You do need to buy the device and get it direct from the Chinese manufacturer. That way you can afford to buy more than one so address multiple needs and the marginal recurring cost is negligible, often zero. There’s no one and done to any of it. It’s like a fitness regimen. My calendar has skin treatment dates blocked off. Once you start seeing results it’s easy to keep going. Kind of addictive actually.

6 Likes

I agree. Tretinoin definitely reduces pore size. I have been using tretinoin from India for about 9 months. I am not sure how long it took to reduce pore size. Fortunately, I don’t have any bad reactions from tretinoin, so I use a lot. It is dirt cheap from India.

4 Likes

That’s true. And I’d like to take this opportunity to thank you, @medaura, for your posts — before I read you, it seemed unimaginable to me. I thought these devices could only be operated by medical professionals. But clearly, it’s not rocket science, and I’m glad I gave it a try.

No one can take care of you the way you can take care of yourself.

6 Likes

That’s a strange article of faith, pounded into us by the mainstream messaging we’re steeped in — that you need to have a professional handle it. I see plenty of horror stories on RealSelf or on skincare centric FB group about the ā€œprofessionalā€ fucking up and the patient is left holding the pieces. In the U.S. at least it’s not the brightest tools in the shed who end up as aestheticians by and large. A lot of these providers are simply ignorant and not that smart to boot and have done little more training on a device than a weekend seminar or YT playlist binging (and far less in depth than you probably would yourself). At times there’s MDs or surgeons providing the treatment but they’re not infallible either and you pay a very steep premium for their credentials. Still they’re a small minority of the providers as it’s more profitable for them to outsource the procedure to staff whose time is far less valuable than their own. I feel much more comfortable and in control performing my own treatments. The only exception is injection. I’m not going to risk vascular occlusion for anything. Learning how to inject in the right plane is also something you can only get proficient at through practice and I have no one to practice on but myself so no. The only exception within the exception is mesotherapy and still I haven’t taken the plunge yet. But all these heat based devices are very simple to operate and much better at getting results from if you do it yourself so you can see what settings or techniques your skin responds well to.

4 Likes

Absolutely valid point!!

2 Likes

I just started using it. I started with adapalene a month earlier.

2 Likes

Stick to it. It’s so good! And make sure to not skimp on sunscreen now.

2 Likes

Bryan Johnson recently released a video stating hbot was one of the best anti aging and skin rejuvenating protocols he’s done. I think he did 90 sessions in 3 months iirc. Consistency is key with hbot to build the effect. Said you can tell when someone has the ā€œhbot glowā€

I’ve been wearing sunscreen most times I go outside. Is it necessary if it is overcast? It’s winter in Australia right now and I walk to work. It was overcast yesterday and I didn’t bother putting sunscreen on.

Every single day!!

:slight_smile:

2 Likes

You can check the UV index for your area, which is probably the best bet. And then couple that with your skin type (something called the Fitzpatrick scale: Table: Fitzpatrick Skin Type Classification-MSD Manual Professional Edition )

There are apps which will tell you when it’s sun-safe outside or not. There are even some that can approximate your rate of vitamin D synthesis based on UV index, skin exposure and skin type.

For me personally, I’ve started wearing sunscreen religiously. I’m a Type II and I develop freckles (and cursed sun spots, urgh) very easily.

1 Like

I’ve been like you most of my life and unfortunately when you’re using tretinoin it’s just not going to cut it. It photosensitizes the skin like crazy and even when it’s overcast you get plenty of UVA radiation, which isn’t blocked by clouds. I think in order to get more good than harm from tret sunscreen needs to be part of the daily routine, like brushing teeth in the morning. Not only when you had steak last night :stuck_out_tongue_closed_eyes:.

@Beth here can hook you up with amazing sunscreen you’ll actually enjoy wearing. I’ve been loving mine!

1 Like

:sob:

ok ok… I’ll do it. What’s the point of going 95% of the way and not putting on sunscreen.

I’d love to hear that. What do you think of this one I currently use? Extreme Sports Mesh Sunscreen Lotion 90mL SPF 50+ — Sun Zapper
Active Ingredients: Octyl Salicylate 5.0% w/w, Diethylamino Hydroxybenzoyl Hexyl Benzoate 4.0% w/w, Ethylhexyl Triazone 3.0% w/w, Bemotrizinol 2.0% w/w, Tris-Biphenyl Triazine 1.7% w/w

I’ve been following Dr. Stanfields advice on skincare which seemed pretty solid. Retinoids. Also utilizing AHA and BHA once a week for each. Every Monday I’m alternating between dermarolling and tretinoin. Also using red light therapy.

Taking collagen peptides, glycine, hyaluronic acid, astaxanthin supplements. A bit more experimental supplements for skin are N-acetyl glucosamine which claims to increase endogenous hyaluronic acid in the skin, and benfotiamine which claims to help prevent the formation of AGEs.

2 Likes

@AustraliaLongevity All those topicals sound very good! I think you could really take things to the next level through a DEP device. See my comment here:

As to the sunscreen, I can’t comment from experience on that particular one and in the end of the day the best sunscreen is the one you’ll continually wear without fail. That being said the chemical sunscreens like that (based on the ingredients you listed) seem to be inferior to the ones based on either zinc oxide (physical sunblock, but hard to find one that doesn’t look ridiculous on the skin) or on tinosorb and other active ingredients approved in Asia and the EU.

1 Like