Wonder what of dose?
Quick look at the study’s listed from 100mg to 2000mg
Review table 1 on page 4
I love GSE. I take it instead of Pycnogenol/pine bark for vascular health (much cheaper, by everything I’ve read essentially the same active compounds, and tons of animal and human published studies with GSE). The main problem with GSE is potential for concentration of pesticides from non-organic grapes when extracted. The only organic GSE I’ve been able to find is from Pure Synergy. it’s more expensive than other GSEs, but it’s still cheaper than Pycnogenol and you get way more proanthocyanidins for your buck IMO.
Effect of Grape Seed Extract and Quercetin on Cardiovascular and Endothelial Parameters in High-Risk Subjects
Effects of grape seed extract in Type 2 diabetic subjects at high cardiovascular risk: a double blind randomized placebo controlled trial examining metabolic markers, vascular tone, inflammation, oxidative stress and insulin sensitivity
Beneficial clinical effects of grape seed proanthocyanidin extract on the progression of carotid atherosclerotic plaques
Love that last study showing outright reversal and even disappearance(!!) of carotid plaques with only 200mg of GSE per day.
Link for the Pure Synergy brand of the GSE you use?
Anyone take grape seed extract as a senolytic? I am mixing 2.8 g with EVOO and taking it once a month for two days in a row. Anyone know the proper protocol for this?
Also heard you shouldn’t take Resveratrol with it as it is an antioxidant and blocks the senolytic effects. I find this strange as Resveratrol is from the grape skin…