Cysteine (from NAC) and Glycine are both produced in adequate amounts by your body from your food. However, as you age, the amount your body effectively utilizes drops off at 30 and becomes a real problem at around 50 and continues to rapidly get worse. That’s why you need to supplement both Glycine and Cysteine (through NAC) at higher and higher levels as you get older.
The link below talks about taurine, glycine and cysteine deficiencies.
Your report is similar to my experience when I Started to take 10 gr of Taurine on empty stomach every morning, it was transformative experience.
What did you notice from taking 10g Taurine? I’ve been taking 1g Taurine, but your comment suggests perhaps I should up that big time too.
Curiously the guidence on the Taurine I bought suggests just 60mg as the recommended daily dose…
I noticed that the Incidence of brainfog was reduced to almost none. There was brain fog one day, when I had more coffee than usual. I had a lot more energy, was in a great mood, and felt much more stress-resilient.I had 10 gr on empty stomach and a few days I allowed myself to have a small amount of coffee, 1- 2 hours after the Taurine. But if I had more coffee than I crashed. (which I did one day). The positive effect showed up already on the first and second day.
I have stopped taken 10 gr Taurine for a few days. Soon I will repeat the experiment. and see of the effect is repeated.
I’ve been hearing people say GlyNAC is useless if you’re under 45 years old. I am aware of the study that showed 2.4g of each NAC and Glycine had no effect on the elderly when it came to boosting glutathione but 4.8g and up did (after two weeks).
I won’t stop glycine since it’s in the collagen peptides I take but I’m wondering if I still should be taking NAC. I’ll be 39 in a month and a half.
Anyone have any input?
See the sections on glutathione, glycine and cysteine here:
10 g of Taurine, is it roughly 1 teaspoon?
10g is a lot, maybe a tablespoon
10 gr taurine is roughly 2 teaspoons.
This is pretty alarming news for those of us who, like you, have a heightened concern about nephrotoxic agents. I think the risk is sufficiently high for me to consider removing rapamycin from my home pharmacy. Thank you for the alert. News like this is what makes the site so valuable, whether rapa is on the menu or not.
Rapamycin can cause nephrotoxicity in some patients with chronic glomerulopathies. Whether the toxicity is solely related to rapamycin, due to the combination of proteinuria and rapamycin, or other unknown factor use is presently undetermined.
10gr is 10gr (the mass) you weight it on a scale. Assuming it is 99% pure compound.
The volume will depend on the purity / cutting agents / flow agents, etc.
yes I weigh the taurine on a scale, before I take it. I have noticed that the volume is approximately 10 ml= 2 teaspoons. I use the powder from NOW food.
Does anyone know if a glutathione blood test is a reliable way to check our glutathione level?
Not really, all available, in 400-500€ range, look intended for research purposes only, as other lab equipment is required to provide results.
BEWARE! NAC can artificially lower your LDL and HDL in blood work according to ConsumerLab.
Regarding the idea of Glycine + NAC, I would speculate that if you are someone who eats a lot of animal protein-based foods, whole grains, and maybe nuts/seeds, then you might not really need the NAC. Take a look at this list of foods highest in cysteine: Top 10 Foods Highest in Cystine (Cysteine)
However, the glycine is a different story. Other than collagen-y kinds of meats (tripe, pigs’ ears, bone broth, other kinds of foods that even pretty healh-conscious folks typically don’t eat much), there aren’t many sources of glycine. Thus, depending on your diet, I can’t help but think that glycine is the most lacking ingredient here for many, except for those who supplement with solid doses of collagen regularly.
What you say makes some sense at first glance. However we know for a fact that after the age of 45, the amount of Glycine and Cysteine our bodies have decreases steadily. I doubt it’s because our diets have changed, but more of the fact that our bodies cannot produce or extract Glycine and Cysteine from food as well as they could when they were younger. That’s why it’s necessary to supplement both.
It reminds me of people saying there’s no use taking rapamycin unless you’re old. Yet in animal models the younger they start the better, and that is true for all interventions with effect.
We are detrimentally aging way before we are considered old.
It’s not clear whether glynac works at all but if it does younger will probably be better.
How early do they recommend to start for dogs?