It’s better than nothing.
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I have used both Zydus and Rapacon and have noticed no difference. I have a supply of both. I use Zydus in making a spray skin lotion because it has a little less filler material to get rid of. Rapacon has many of its drugs approved by the FDA and has a presence in the U.S. Since rapamycin use is small compared to other drugs, it is not on the top 100 prescription drug list, so it is probably not a priority for them.
After using both for quite some time, I really don’t see any need to pay more for Zydus.
Their subsidiary Syngene has a U.S. office and has Amgen, Zoetis, GlaxoSmithKline, and Bristol Myers Squibb as clients.
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That’s actually a pretty good point. I might switch my order to Rapacan then. Thanks for sharing!
I have the same feelings about Biocon. It’s a major player that sells many generics to the US and has received FDA approval for many of its drugs. It’s at least as reputable as a brand as any other generic. Doesn’t mean that it has no risk, just that there’s no reason to believe it’s any worse than Zydus.
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I have not yet started but this is important information. I would like to know which blood tests do you regularly have tested. And how often?
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Hi - welcome to the site! I recommend you review this long discussion on the topic of rapamycin and blood testing: What blood tests are people taking?, Any rapamycin specific ones?
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I take Zydus brand and I can confirm it is the real deal.
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DeStrider, how do you know? The physical changes that noticeable? What dose and how are you dosing. And how old are you?
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I know because I get the Rapamycin side effects like canker sores, rashes, acne and bacterial infections. Before I took Zydus, I did not have these problems.
If it was a sugar pill this wouldn’t happen.
Also someone did a chemical analysis of Zydus and Rapacon and they were authentic.
Also, this is a vital medication for transplant receivers. If there was no Rapamycin in the pills, people would die and the government would shut the companies down.
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Although it has been established that ROS plays an important role in the development of type 2 diabetes, [4] what this study does not explain is why there is no titanium dioxide found in non-diabetic pancreas.
It is inconceivable that the non-diabetic patients were somehow able to escape complete exposure to titanium dioxide. Yet their pancreas show absolutely zero sign of titanium dioxide contamination. Why does titanium dioxide accumulate in diabetic pancreas and not in non-diabetic pancreas?
Some of my readers, as a response to this article, have commented that although they have been tested positive for the presence of titanium dioxide, the compound is not detected in their pancreas. Coincidentally, the readers are also non-diabetic.
One of the hallmarks of diabetes is the imbalance between NADH and NAD+. NADH is overproduced during the influx of elevated blood glucose to the glycolytic and Krebs cycle pathways and activation of the polyol pathway; while NAD+ is depleted by overactivation of poly ADP ribose polymerase that uses NAD+ as its substrate. The consequence of NADH/ NAD+ ratio imbalance is initially reductive stress that eventually leads to oxidative stress and oxidative damages to DNA, lipids, and proteins. NADH is a reducing agent. Overaccumulation of NADH results in severe reductive stress. Is it possible that the pancreas accumulate titanium dioxide, an extremely potent oxidizing agent, in an attempt to regain redox homeostasis? Except in this case, titanium dioxide happens to be a trojan horse.
https://www.linkedin.com/pulse/titanium-dioxide-trojan-horse-doris-loh/
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I have Zydus - Siromus. I have not had it tested, but it did seem to have an effect on sleep. I will take my second dose soonish (probably this year).
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Zydus. I’ve been taking Rapamycin for three months now.
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Rapacan (Sirolimus 1mg) tablets by Biocon (US FDA approved company) costing
175 USD for 200 tablets and
350 USD for 500 tablets.
Price includes shipping charges.
My contact Girish Bhattad, Forveda Online Private Limited
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I’ve ordered from Girish as well… twice now; once for Biocon, once for Zydus. Both times received what I ordered quickly and without any problem.
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wise.com using my bank CC the first time and my DC the second, just because using the DC was cheaper.
I was a bit reluctant to use CC of Dc. With your experience I will use wise.com next time.
Have you purchased any other meds from them?
Nope, I’ve only purchased rapa. From what I’ve read wise is very secure.
Thanks for recommending Girish. I wouldn’t have had the confidence to send $ nor be confident of the product. It’s in the mail.