Experience with GLP-1s

Yes, I’m aware. I do work out, preferring HIIT, but I’m a skinny guy and I don’t use creatine. I doubt that Cystatin C would make a difference.

Steve,

How does Cagrilintide work for you? Does it stop your hunger, cause nausea, or just stop your desire for food?
I ask because so far my favorite glp is retatrutide. It blunts a decent amount of my cravings and l get satisfied on less food but l still get hunger pangs 3 to 4 hours later though.

Like most things, it’s dose dependent. It was developed to specifically curb hunger to enhance the poor weight loss performance of semaglutide. And “poor” is relative to the newer GLP1’s like tirz and reta.

When I first tried Cagri I started at too high a dose, 1.0mg and it killed all hunger for 3 or 4 days, did not care at all about eating. So not sure if that is “hunger” or “desire” but maybe a bit more on the desire side of the equation. Just did not enjoy eating and did not feel hungry.

I’ve never experienced nausea with any GLP1 and none with Cagri either. Very few of our local clients have experienced nausea with GLP1 either, I’d say less than 0.3%

I’m just trying to curb the THC induced munchies a bit more than reta does :slight_smile:

Reta is still my go to GLP1 and it will continue to be for the foreseeable future.

I’m not terribly concerned about feeling hungry, that just reminds us we are human :slight_smile: It’s how one deals with that feeling that matters. I’m hungry every day when I get home from work, enjoy a nice meal and feel full, another human reaction :slight_smile:

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I was thinking about this after I wrote it. Not entirely true as I have experienced nausea under very specific conditions, over eating when I was on Tirz. If I ate a larger than “normal” meal I would experience some nausea for a bit. That was in the first 8 months of this journey. With Reta that doesn’t happen, I can enjoy a nice steak and not feel that. I’m just not sure if it was the GLP1 type or if my system has become fully acclimated to the new normal.

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Great info Steve. Thanks

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