There is a forgotten herb called dinh lang which has been shown to significantly extend lifespan in both mice and rats. I think it would be a good candidate for the ITP trials, if anyone knows the ITP scientists. It also worked synergistically with Deprenyl. The following lifespan data quoted below comes from an archived thread on the Longecity forum that I found on Google search. Scientific name is polyscias fruticosa / policias fruticosum. It might also be known as ming aralia.
Dinh lang extract and deprenyl have some additive effects on prolonging the lifespan of OFA-1 mice. (Acta Physiologica Hungarica 79(2): 119-124 1992)
Group Maximum Lifespan
control 133 weeks
dinh lang 170
deprenyl 162
both 180
This also works in Wistar rats as well. (Acta Physiologica Hungarica 75: 301-302 1990)
It might be a good supplement especially for older people, but it looks like deprenyl is easier to obtain than Ding lang root extract. Does anyone know of a source for the Dinglang root extract?
“Dinh lang root extract treatment (10 mg/kg/day, orally) for 5 weeks restored cognitive ability in a groupof senescent (22-24-month-old) rats that were unable to develop conditioned avoidance response [6].
The same treatment for 4 weeks significantly improved the performance of young mice and improved retention in both 5-month-old and 19-20-month-old mice.”
True, although the roots and leaves of herbs often contain similar bioactive compounds. Much of the published research used an extract from the leaves. And in one paper, researchers identified 8 unique compounds in the leaves and roots. But if the root extract is available for purchase somewhere I’d buy it. Otherwise, stuck with the tea and have to hope it contains some of the same unknown chemical responsible for the impressive life extension.