Buy Rapamycin Online - List of Reliable Pharmacies

A great price and good results! Thanks for sharing.

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If my peptide friends an I end up doing a group buy deal with Janoshik testing why not consider going in with us? Now that i feel a little more confident about buying from India I will make sure I am getting Zydus brand.You would be more than welcome to join. :grinning:

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Thank you for your kind invitation, and I don’t mind testing in principle, but frankly don’t see the point in this particular case. I can already tell you with 99% confidence what the test will find: 1mg rapamycin in a single Biocon pill. What are the odds that this manufacturer (not exactly an obscure fly by night company!) is selling a pill that doesn’t have the right amount of the correct active agent: extremely remote. So this test is of no interest to me, because the result is already preordained. What does interest me is whether the coating on the pill is enteric (doubts because of the scoring on the pill), because that affects bioavailability, and it is that which is in question, not if the pill contains rapamycin (which I have zero doubt about). Yet who cares that it’s rapamycin, if I can only absorb 30% of it because it has a subpar coating that doesn’t get past the stomach acid. And that is not something that this lab will tell you about
 so what’s the point?

But, as a fallback I have a plan as to how to test for the the bioavailability of this pill, which I’ve described in a previous post. We’ll see.

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Did you see these threads?

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No worries and please keep us posted on your plan. I am very interested in your results! good luck!

I did see the test with the pill form earlier but not the powder test. Thanks! What I know about testing was learned in regards to lyophilized peptides so I am wondering if pharma pills in a blister pack is a different animal. And by different what i mean is this- with lyophilized peptides (the dried pucks in the bottom of a vial) each batch could be different. So each time there is a large group buy the peps are tested for purity and quantity. Is that not the case with pharma pills? I think the valisure test of the rapa pill form posted here was from 2019. So is it still good today? I want to learn the difference between peps and pharma pills.Thank you so much for chiming in!

Yes, Pharma produces drugs in batches (much larger batches than peptide companies I’m sure), and there definitely could be some variance in product content and quality. But I suspect that the quality processes of major Pharma companies (e.g. the larges Pharma in US, Europe and China and India) are probably pretty good most of the time; they ship internationally, if they ship into the USA they are governed (but not well monitored) by the FDA, and so generally I think they are likely to be of reasonably good quality. Of course there are non-compliant batches that do make it through, but I think it would take a lot of testing to identify these issues; the key issue really is contaminants (e.g. nitrosamines, which can be created in the manufacturing process and are linked with cancer), but unless you know what to look for in the testing, you’re likely to miss these contaminants. I don’t think its a job that laypeople would likely be competent at (nor even the average analytical chemistry lab).

You might feel more confident in your sources with a simple purity test, but I really think you’re missing out on the complexity of Pharma drug testing process and what contaminants to look for. And if you don’t know what you’re doing, you’re probably not doing what you think you are doing.

This is complex biochemistry, and if you’re still learning about HPLC you’re likely not at the PHD level of chemistry required to truly do good quality testing on supplies, and are thus just wasting your money and gaining false confidence.

Drug recalls happen all the time, but I doubt simple consumer quality testing ever would find these issues that drive the recalls:

https://www.fda.gov/drugs/drug-safety-and-availability/drug-recalls

Related reading:

https://www.sciencedirect.com/science/article/abs/pii/S0273230023000235#:~:text=N-nitrosamines%20are%20carcinogenic%20impurities,significant%20health%20risk%20to%20patients.

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@desertshores @Guywholikessleep Awesome! Not a bad price. Can i ask what brand you both ordered? What manufacturer? Thanks!

I reached out to Jagdish Nikose and will be placing an order from him. @desertshores mentioned that he was a pharmacist and Jagdish confirmed that. He was very patient and answered all of my questions. I asked him about the differences in coating on the Eris brand versus the Zydus brand and he took the time to take pictures of the two boxes and show me as well as explain to me about the outer part of the pill. He explained that both pills were “film coated” as it shows on the boxes and he assured me that both work the same. After all of the posts on here about him and after speaking to him myself I think he is legit and a pretty smart guy. I am now comfortable buying either brand and wanted to share this with you in hopes it brings you some clarity on this as well. If you look in the upper left corner you will see the words “film coated” on both boxes. Maybe Zydus just adds something else as well? But according to Jagdish both do the same thing. Have a great sunday!


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Yes, Jagdish is a gem. I have found him to be responsible and trustworthy. I haven’t had any problems with any of the meds I have bought from him over the past 2 years.

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Good to know and thanks!

Well, this is a mess. The poster @Rapan in the other thread posted:

“Enteric delivery is not the issue here. Rapamune from Pfizer has no enteric coating.
The issue is the solubilization of the drug which requires advanced formulation.”

Sooo, if this is the case, then there is no point in the test for enteric coating I planned above! Now what?

The one thing that puzzles me, is that if these Indian generics were approved for patients, then presumably they can’t have drastically different bioavailability than the Pfizer Rapamune, otherwise it throws off the dosing completely. You would think they’d test this before approving them for the domestic market, or even distributing in the USA (Zydus?)
 but who knows, I put nothing beyond these companies and regulators.

I don’t know what to think here. But then again we have many people on this board taking these generics and seeing some kind of effects, blood levels etc., so
:person_shrugging:

I don’t know the answer. I have not done blood tests for Rapamycin levels, but I have done substantial testing on the effects of Rapamycin (which are posted in another thread). I used Zydus and Rapacan.
(at the same time).

Hence AIUI I have solid evidence that it works.

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I get the side effects I expect for the doses of Zydus that I take. It should be fine.

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I have done the blood tests at 2 hour peak and 2 week trough. They worked out to the old graph Rapadmin always used. Never tested at 2 days.

I did work my way up to a high dose for a while, had big problems with lipids and fasting glucose, a few mouth sores, decided it wasn’t worth it.

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Janoshik might be able to do a purity testing, wonder if that would offer info about the coating and bioavailability.




Hello everyone, I just want to let you know that 24 days ago I placed an order for 48 tablets of 1 mg Sirolimus from the Zydus brand on DropshipMd. As you all know, I’m from Mexico, and I was afraid my order would get stuck in customs. However, the seller assured me that there wouldn’t be any issues, so I decided to trust them, and it seems there was no problem at all. They used the EMS postal service, and here in Mexico, that company operates through Correos de MĂ©xico. It seems that Correos de MĂ©xico is more lenient with packages or maybe they’re just too lazy to check them, heheh.

Well, that’s my experience in case it helps anyone from Mexico.

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@RapAdmin Do you know who typically bears the loss when a package of medicine is lost in the mail or seized by customs? Does the shipper usually send it again?

I have a courier who is going to India to pick up the meds I am going to reorder so that it won’t get lost again.

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I have no experience in this area
 never lost a package or had one seized (knocking on wood). I think it is a vendor by vendor decision, best discussed prior to the purchase from the vendor. I’ve seen both situations (shipper covers, or buyer eats the cost) in posts on the forum here. I don’t have a good feeling for what is more common.

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I’m going to eat the cost of the lost package and hope that it turns up through the USPS one day. Even though I’ve lost 1800 pills, re-ordering it from India is still cheaper than paying the original price in the USA for my parents!!!

My courier is already in Mumbai and will bring me the meds next week. Maulik is preparing the new shipment.

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