Wellbutrin XL and Wellbutrin SR are different formulations of the antidepressant bupropion. Both Wellbutrin XL and Wellbutrin SR may cause weight gain or weight loss, but weight loss is more common. Not everyone taking these drugs will experience a change in weight.
Weight changes are considered a side effect for both Wellbutrin XL and Wellbutrin SR. Studies of Wellbutrin XL show that 23% of people taking a dose of 150 to 300 mg per day lost 5 pounds or more. In the same studies, 11% of people gained more than 5 pounds.
Studies of Wellbutrin SR show that 14% of people taking a dose of 300 mg per day lost more than 5 pounds. At a dose of 400 mg, 19% of people lost more than 5 pounds. In the same studies, a small percentage of people gained more than 5 pounds: 3% taking 300 mg and 2% taking 400 mg.
I have taken bupropion. It definitely does cause you to not feel hungry, but in the way a stimulant does. For me, it was a very unpleasant drug but for people who need the neurochemical changes it does, it can be great. But I will say that it has a potent āfeelingā and I think it could be tough to take it if you donāt need the feeling that it provides.
When I took semaglutide however, completely different story. No desire to eat, no other effect. Perfect target perfect drug for me.
Bupropion and naltrexone are combined in the weight loss medication known as Contrave.
Bupropion mostly caused me anxiety.
āCONTRAVE combines 2 medications that together reduce hunger and control cravings to help you lose weight and keep it off: bupropion HCl and naltrexone HCl.ā