Astaxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemia. Atherosclerosis

From;

“In another trial, daily astaxanthin doses of 6, 12, or 18 mg decreased triglycerides and increased HDL cholesterol and improved blood flow in microcirculation models [15].”*

*[15] Yoshida H, Yanai H, Ito K, et al. Administration of natural astaxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemia. Atherosclerosis. 2010;209:520–3.

Copy of paper is behind a paywall.

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I think this is a key finding many of us were looking for. In order to beat cholesterol, we need to increase our HDL ‘good’ cholesterol.

There are a plethora of compound’s to address cholesterol, many have been discussed. This is just one more.

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I think the evidence now points in the direction that raising HDL as a target does not improve outcomes. The target is to lower apo b

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Peter Attia said on a recent (sometime in the past year, on an CVD-focused podcast) that there have been many tests of compounds that increase HDL, but no evidence that boosting HDL reduces risk of atherosclerosis. It seems associative, but not causal.

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Yes, it is probably better to lower LDL and triglycerides.